3-hydroxybutyric acid has been researched along with Alcohol Abuse in 29 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Alcoholism may cause hypoglycemia accompanying with AKA, due to a low carbohydrate intake, the inhibition of gluconeogenesis, and reduced hepaticglycogen storage as seen in this case." | 3.81 | Case of alcoholic ketoacidosis accompanied with severe hypoglycemia. ( Iwanaga, Y; Matsuzaki, T; Shiraishi, W; Yamamoto, A, 2015) |
| "Data from 191 post-mortem cases where post-mortem blood beta-hydroxybutyrate (βHB) and acetone concentrations and vitreous humor glucose concentrations (where available) had been measured were retrospectively investigated to determine the markers required to identify and distinguish between Alcoholic Ketoacidosis (AKA), Diabetic Ketoacidosis (DKA) and Hyperosmolar Hyperglycemic State (HHS)." | 3.78 | Investigation of markers to indicate and distinguish death due to alcoholic ketoacidosis, diabetic ketoacidosis and hyperosmolar hyperglycemic state using post-mortem samples. ( Andrews, R; Dhillo, W; Hockenhull, J; Paterson, S, 2012) |
| "Alcoholic ketoacidosis (AKA) is an important and probably underdiagnosed differential diagnosis for metabolic acidosis with an increased anion gap." | 2.38 | [Alcoholic ketoacidosis]. ( Caspar, CB; Iten, PX; Jost, R; Risti, B; Russi, EW; Speich, R, 1993) |
| "Originally described in diabetic ketoacidosis, renal vacuoles can be found in other ketogenic states such as alcoholic ketoacidosis (AKA), starvation, and hypothermia, underpinned by deranged fatty acid metabolism." | 1.91 | Subnuclear renal tubular vacuoles in alcohol use disorder. ( Auld, FM; Milroy, CM; Parai, JL, 2023) |
| "The main background of ketoacidosis was considered as alcohol abuse in 6 cases, diabetes in 5, malnutrition in 3, and hypothermia and infection in 1 case each." | 1.72 | Clinicopathologic Appearance of Advanced Ketoacidosis With Basal Vacuolation in Renal Tubules. ( Hata, Y; Ichimata, S; Nishida, N, 2022) |
| "Patients with alcohol use disorder (AUD) present with important emotional, cognitive, and social impairments." | 1.56 | Gut Microbiota-Induced Changes in β-Hydroxybutyrate Metabolism Are Linked to Altered Sociability and Depression in Alcohol Use Disorder. ( Amadieu, C; Bindels, LB; Cani, PD; Colet, JM; Coste, V; de Timary, P; Delzenne, NM; Dricot, L; Furgiuele, S; Le Roy, T; Leclercq, S; Leyrolle, Q; Neyrinck, AM; Petit, G; Quoilin, C; Stärkel, P; Tagliatti, V; Verbeke, K, 2020) |
| "Fetal ketoacidosis with hypoxic-ischemic brain damage was determined to be the cause of death." | 1.48 | Detection of elevated ketone bodies by postmortem 1H-MRS in a case of fetal ketoacidosis. ( Fliss, B; Gascho, D; Heimer, J; Martinez, RM; Zoelch, N, 2018) |
| "Diabetes and alcohol abuse may cause severe metabolic disturbances that can be fatal." | 1.39 | Assessment of Traub formula and ketone bodies in cause of death investigations. ( Keltanen, T; Lindroos, K; Palo, JU; Partanen, T; Sajantila, A; Valonen, T, 2013) |
| "Alcohol ketoacidosis is a frequently missed diagnosis, but is well described in the literature." | 1.39 | Ketoacidosis and trace amounts of isopropanol in a chronic alcoholic patient. ( Dwyer, JB; Tamama, K, 2013) |
| "To examine the effect of ketoacidosis on renal cells in isolation, five cases of lethal alcoholic ketoacidosis without hyperglycemia were examined (vitreous humor β-hydroxybutyrate: 6." | 1.38 | Basal renal tubular epithelial cell vacuolization and alcoholic ketoacidosis. ( Byard, RW; Zhou, C, 2012) |
| "Vitreous BHB was a marker of diabetic ketoacidosis when above 6." | 1.38 | Postmortem vitreous beta-hydroxybutyrate: interpretation in a forensic setting. ( Heninger, M, 2012) |
| "In six further cases a diabetic ketoacidosis (DKA) was diagnosed as the cause of death." | 1.31 | Beta-hydroxybutyric acid--an indicator for an alcoholic ketoacidosis as cause of death in deceased alcohol abusers. ( Iten, PX; Meier, M, 2000) |
| "Alcoholic ketoacidosis is rare and must be considered in the differential diagnosis of any alcoholic patient with acidosis." | 1.29 | [Alcoholic ketoacidosis. Apropos of a case with coma]. ( Jobard, JM, 1993) |
| "Forensic pathologists are familiar with alcohol abusers, who are found dead and in whom the cause of death cannot be ascertained." | 1.29 | Alcoholic ketoacidosis as a cause of death in forensic cases. ( Felby, S; Nielsen, E; Theilade, P; Thomsen, JL, 1995) |
| " Male Sprague-Dawley rats were rendered physically dependent on ethanol by intragastric administration of ethanol at a dosage of 9 to 15 grams per kilogram per day over a 4-day period." | 1.27 | Suppression of an ethanol withdrawal syndrome in rats by butyrate, lactate and beta-hydroxybutyrate. ( Derr, M; Derr, RF; Draves, K, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (17.24) | 18.7374 |
| 1990's | 8 (27.59) | 18.2507 |
| 2000's | 2 (6.90) | 29.6817 |
| 2010's | 10 (34.48) | 24.3611 |
| 2020's | 4 (13.79) | 2.80 |
| Authors | Studies |
|---|---|
| Ichimata, S | 1 |
| Hata, Y | 1 |
| Nishida, N | 1 |
| Ahlström, S | 1 |
| Ahlner, J | 1 |
| Jönsson, AK | 1 |
| Green, H | 1 |
| Auld, FM | 1 |
| Parai, JL | 1 |
| Milroy, CM | 1 |
| Leclercq, S | 1 |
| Le Roy, T | 1 |
| Furgiuele, S | 1 |
| Coste, V | 1 |
| Bindels, LB | 1 |
| Leyrolle, Q | 1 |
| Neyrinck, AM | 1 |
| Quoilin, C | 1 |
| Amadieu, C | 1 |
| Petit, G | 1 |
| Dricot, L | 1 |
| Tagliatti, V | 1 |
| Cani, PD | 1 |
| Verbeke, K | 1 |
| Colet, JM | 1 |
| Stärkel, P | 1 |
| de Timary, P | 1 |
| Delzenne, NM | 1 |
| Heimer, J | 1 |
| Gascho, D | 1 |
| Fliss, B | 1 |
| Martinez, RM | 1 |
| Zoelch, N | 1 |
| Zhou, C | 2 |
| Gilbert, JD | 1 |
| Yool, A | 1 |
| Byard, RW | 2 |
| Palmiere, C | 1 |
| Mangin, P | 1 |
| Werner, D | 1 |
| Keltanen, T | 1 |
| Sajantila, A | 1 |
| Palo, JU | 1 |
| Partanen, T | 1 |
| Valonen, T | 1 |
| Lindroos, K | 1 |
| Matsuzaki, T | 1 |
| Shiraishi, W | 1 |
| Iwanaga, Y | 1 |
| Yamamoto, A | 1 |
| Hassan, HM | 1 |
| Cooper, GA | 1 |
| Hockenhull, J | 1 |
| Dhillo, W | 1 |
| Andrews, R | 1 |
| Paterson, S | 1 |
| Rehman, HU | 1 |
| Heninger, M | 1 |
| Dwyer, JB | 1 |
| Tamama, K | 1 |
| Oster, JR | 1 |
| Epstein, M | 1 |
| Derr, RF | 1 |
| Draves, K | 1 |
| Derr, M | 1 |
| Adner, N | 1 |
| Nygren, A | 1 |
| Davin, A | 1 |
| Vion-Dury, J | 1 |
| Viout, P | 1 |
| Cozzone, PJ | 1 |
| Hooper, RJ | 1 |
| Jobard, JM | 1 |
| Caspar, CB | 1 |
| Risti, B | 1 |
| Iten, PX | 2 |
| Jost, R | 1 |
| Russi, EW | 1 |
| Speich, R | 1 |
| Denmark, LN | 1 |
| Thomsen, JL | 1 |
| Felby, S | 1 |
| Theilade, P | 1 |
| Nielsen, E | 1 |
| Hirsch, S | 1 |
| De La Maza, MP | 1 |
| Petermann, M | 1 |
| Bunout, D | 1 |
| Pounder, DJ | 1 |
| Stevenson, RJ | 1 |
| Taylor, KK | 1 |
| Meier, M | 1 |
| Testar, X | 1 |
| Llobera, M | 1 |
| Herrera, E | 1 |
| Casazza, JP | 1 |
| Veech, RL | 1 |
2 reviews available for 3-hydroxybutyric acid and Alcohol Abuse
| Article | Year |
|---|---|
Acid-base aspects of ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alcoholism; Alkalosis | 1984 |
[Alcoholic ketoacidosis].
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Alcoholism; Diagnosis, Differential; Ethanol; Female | 1993 |
27 other studies available for 3-hydroxybutyric acid and Alcohol Abuse
| Article | Year |
|---|---|
Clinicopathologic Appearance of Advanced Ketoacidosis With Basal Vacuolation in Renal Tubules.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Epithelial Cells; Glucose; Humans; Ketosis; Perilipin-2; Retrospe | 2022 |
The Importance of BHB Testing on the Post-Mortem Diagnosis of Ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Diabetic Ketoacidosis; Diagnosis; Humans; Hypothermia | 2021 |
Subnuclear renal tubular vacuoles in alcohol use disorder.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Diabetic Ketoacidosis; Epithelial Cells; Fatty Liver; Forensic Pa | 2023 |
Gut Microbiota-Induced Changes in β-Hydroxybutyrate Metabolism Are Linked to Altered Sociability and Depression in Alcohol Use Disorder.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Animals; Anti-Bacterial Agents; Bacteria; Behavior, Animal; Brain | 2020 |
Detection of elevated ketone bodies by postmortem 1H-MRS in a case of fetal ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Acetone; Acidosis, Lactic; Alcoholism; Cerebrum; Fasting; Female; Fetal Blood | 2018 |
Basal epithelial formalin pigment deposition in the kidneys--a useful marker for ketoacidosis at autopsy.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Aged, 80 and over; Alcoholism; Biomarkers; Case-Control Studies; | 2013 |
Postmortem distribution of 3-beta-hydroxybutyrate.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Case-Control Studies; Death, Sudden; Diabetic Ketoacidosis; Femal | 2014 |
Assessment of Traub formula and ketone bodies in cause of death investigations.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Alcoholism; Algorithms; Autopsy; Biomarkers; Blood Gl | 2013 |
Case of alcoholic ketoacidosis accompanied with severe hypoglycemia.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Coma; Dietary Carbohydrates; Fluid Therapy; Gluconeogenesis; Gluc | 2015 |
Determination of beta-hydroxybutyrate in blood and urine using gas chromatography- mass spectrometry.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Biomarkers; Drug Stability; Gas Chromatography-Mass Spectrometry; | 2009 |
Investigation of markers to indicate and distinguish death due to alcoholic ketoacidosis, diabetic ketoacidosis and hyperosmolar hyperglycemic state using post-mortem samples.
Topics: 3-Hydroxybutyric Acid; Acetone; Adult; Aged; Alcoholism; Biomarkers; Diabetic Ketoacidosis; Female; | 2012 |
Basal renal tubular epithelial cell vacuolization and alcoholic ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Alcoholism; Case-Control Studies; Epithelial Cells; Female; Fore | 2012 |
A woman with ketoacidosis but not diabetes.
Topics: 2-Propanol; 3-Hydroxybutyric Acid; Abdominal Pain; Acidosis; Adult; Alcoholism; Diabetic Ketoacidosi | 2012 |
Postmortem vitreous beta-hydroxybutyrate: interpretation in a forensic setting.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Aged; Aged, 80 and over; Alcoholism; Biomarkers; Central N | 2012 |
Ketoacidosis and trace amounts of isopropanol in a chronic alcoholic patient.
Topics: 2-Propanol; 3-Hydroxybutyric Acid; Acetone; Adult; Alcoholism; Blood Glucose; Chronic Disease; Human | 2013 |
Suppression of an ethanol withdrawal syndrome in rats by butyrate, lactate and beta-hydroxybutyrate.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Animals; Butyrates; Butyric Acid; Citric Acid Cycle; Humans; Hydr | 1983 |
Insulin effect in chronic alcoholics during alcohol withdrawal.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Alcoholism; Blood Glucose; C-Peptide; Growth Hormone; Humans; Hy | 1982 |
Rapid evaluation of ethanol content and metabolism in human plasma using quantitative proton magnetic resonance spectroscopy.
Topics: 3-Hydroxybutyric Acid; Acetates; Acetone; Alcohol Drinking; Alcoholism; Biomarkers; Ethanol; Humans; | 1994 |
Alcoholic ketoacidosis: the late presentation of acidosis in an alcoholic.
Topics: 3-Hydroxybutyric Acid; Acidosis; Alcoholism; Analgesics; Antiemetics; Blood Chemical Analysis; Fluid | 1994 |
[Alcoholic ketoacidosis. Apropos of a case with coma].
Topics: 3-Hydroxybutyric Acid; Adult; Alcoholism; Diagnosis, Differential; Humans; Hydroxybutyrates; Ketosis | 1993 |
The investigation of beta-hydroxybutyrate as a marker for sudden death due to hypoglycemia in alcoholics.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Aged, 80 and over; Alcoholism; Cause of Death; Death, Sudden; Ev | 1993 |
Alcoholic ketoacidosis as a cause of death in forensic cases.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Alcoholis | 1995 |
Lipid turnover in alcoholics before and after an ethanol load.
Topics: 3-Hydroxybutyric Acid; Acetates; Acetoacetates; Adult; Alcoholism; Biopsy, Needle; Ethanol; Fatty Ac | 1998 |
Alcoholic ketoacidosis at autopsy.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Alcoholis | 1998 |
Beta-hydroxybutyric acid--an indicator for an alcoholic ketoacidosis as cause of death in deceased alcohol abusers.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Aged, 80 and over; Alcoholism; Cause of Death; Diabetic Ketoacid | 2000 |
Comparative metabolic effects of chronic ethanol intake and undernutrition in pregnant rats and their fetuses.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Animals; Blood Proteins; Body Weight; Female; Fetal Alcohol Spect | 1988 |
The production of 1,2-propanediol in ethanol treated rats.
Topics: 3-Hydroxybutyric Acid; Alcoholism; Animals; Cytochrome P-450 Enzyme System; Enzyme Induction; Humans | 1985 |