3-hydroxybutyric acid has been researched along with Aging in 64 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study was designed to evaluate the effects of age on the efficacy of the ketogenic diet in suppressing seizures evoked by tail-vein infusion of pentylenetetrazole (PTZ)." | 3.70 | Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet. ( Bough, KJ; Eagles, DA; Han, FT; Valiyil, R, 1999) |
| "It is widely accepted that ketosis (increased blood ketone body levels, e." | 2.72 | Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases. ( Ari, C; Brunner, B; Kovács, Z, 2021) |
| "Results indicate that seizure threshold was significantly elevated with increasing ketogenic ratios (i." | 1.30 | Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the Rat. ( Bough, KJ; Chen, RS; Eagles, DA, 1999) |
| "Urea levels were highest in controls, and lowest in cafeteria rats fed from day 30, a consequence of the different setting of nitrogen sparing induced by the timing of initiation of cafeteria feeding." | 1.29 | Long-term effects of cafeteria diet feeding on young Wistar rats. ( Alemany, M; Arola, L; Salvadó, J; Segués, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 16 (25.00) | 18.7374 |
| 1990's | 20 (31.25) | 18.2507 |
| 2000's | 12 (18.75) | 29.6817 |
| 2010's | 9 (14.06) | 24.3611 |
| 2020's | 7 (10.94) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, L | 1 |
| Chen, P | 1 |
| Xiao, W | 1 |
| Stekovic, S | 1 |
| Hofer, SJ | 1 |
| Tripolt, N | 1 |
| Aon, MA | 1 |
| Royer, P | 1 |
| Pein, L | 1 |
| Stadler, JT | 1 |
| Pendl, T | 1 |
| Prietl, B | 1 |
| Url, J | 1 |
| Schroeder, S | 1 |
| Tadic, J | 1 |
| Eisenberg, T | 1 |
| Magnes, C | 1 |
| Stumpe, M | 1 |
| Zuegner, E | 1 |
| Bordag, N | 1 |
| Riedl, R | 1 |
| Schmidt, A | 1 |
| Kolesnik, E | 1 |
| Verheyen, N | 1 |
| Springer, A | 1 |
| Madl, T | 1 |
| Sinner, F | 1 |
| de Cabo, R | 1 |
| Kroemer, G | 1 |
| Obermayer-Pietsch, B | 1 |
| Dengjel, J | 1 |
| Sourij, H | 1 |
| Pieber, TR | 1 |
| Madeo, F | 1 |
| Suissa, L | 1 |
| Flachon, V | 1 |
| Guigonis, JM | 1 |
| Olivieri, CV | 1 |
| Burel-Vandenbos, F | 1 |
| Guglielmi, J | 1 |
| Ambrosetti, D | 1 |
| Gérard, M | 1 |
| Franken, P | 1 |
| Darcourt, J | 1 |
| Pellerin, L | 1 |
| Pourcher, T | 1 |
| Lindenthal, S | 1 |
| Morittu, VM | 1 |
| Minuti, A | 1 |
| Spina, A | 1 |
| Riboni, MV | 1 |
| Piccioli-Cappelli, F | 1 |
| Trevisi, E | 1 |
| Britti, D | 1 |
| Lopreiato, V | 1 |
| Sharma, R | 1 |
| Ramanathan, A | 1 |
| Han, YM | 1 |
| Ramprasath, T | 1 |
| Zou, MH | 1 |
| Park, JS | 1 |
| Kim, YJ | 1 |
| Kovács, Z | 1 |
| Brunner, B | 1 |
| Ari, C | 1 |
| Newman, JC | 2 |
| Verdin, E | 2 |
| Kim, DH | 1 |
| Park, MH | 1 |
| Ha, S | 1 |
| Bang, EJ | 1 |
| Lee, Y | 1 |
| Lee, AK | 1 |
| Lee, J | 1 |
| Yu, BP | 1 |
| Chung, HY | 1 |
| Edwards, C | 1 |
| Copes, N | 1 |
| Bradshaw, PC | 1 |
| Kojima-Yuasa, A | 1 |
| Yamamoto, T | 1 |
| Yaku, K | 1 |
| Hirota, S | 1 |
| Takenaka, S | 1 |
| Kawabe, K | 1 |
| Matsui-Yuasa, I | 1 |
| Crane, EM | 1 |
| Munro, JC | 1 |
| Bourgon, SL | 1 |
| Diel de Amorim, M | 1 |
| Ventura, R | 1 |
| Fredeen, AH | 1 |
| Montanholi, YR | 1 |
| Studzinski, CM | 1 |
| MacKay, WA | 1 |
| Beckett, TL | 1 |
| Henderson, ST | 1 |
| Murphy, MP | 1 |
| Sullivan, PG | 1 |
| Burnham, WM | 1 |
| Balietti, M | 2 |
| Giorgetti, B | 2 |
| Fattoretti, P | 2 |
| Grossi, Y | 1 |
| Di Stefano, G | 2 |
| Casoli, T | 2 |
| Platano, D | 2 |
| Solazzi, M | 2 |
| Orlando, F | 1 |
| Aicardi, G | 2 |
| Bertoni-Freddari, C | 2 |
| Plourde, M | 2 |
| Tremblay-Mercier, J | 1 |
| Fortier, M | 1 |
| Pifferi, F | 1 |
| Cunnane, SC | 2 |
| Freemantle, E | 1 |
| Vandal, M | 1 |
| Tremblay Mercier, J | 1 |
| Poirier, J | 1 |
| Norouzian, MA | 1 |
| Valizadeh, R | 1 |
| Vahmani, P | 1 |
| Żarnowski, T | 1 |
| Chorągiewicz, T | 1 |
| Tulidowicz-Bielak, M | 1 |
| Thaler, S | 1 |
| Rejdak, R | 1 |
| Żarnowski, I | 1 |
| Turski, WA | 1 |
| Gasior, M | 1 |
| Swithers, SE | 2 |
| McCurley, M | 1 |
| Hagopian, K | 1 |
| Ramsey, JJ | 1 |
| Weindruch, R | 1 |
| Ohtsu, H | 1 |
| Sato, K | 1 |
| Nishida, H | 1 |
| Akiba, Y | 1 |
| Vannucci, SJ | 1 |
| Simpson, IA | 1 |
| Lust, WD | 1 |
| Pundik, S | 1 |
| Zechel, J | 1 |
| Zhou, Y | 1 |
| Buczek, M | 1 |
| Selman, WR | 1 |
| Coverdale, JA | 1 |
| Tyler, HD | 1 |
| Quigley, JD | 3 |
| Brumm, JA | 1 |
| Regen, DM | 1 |
| Callis, JT | 1 |
| Sugden, MC | 1 |
| Roeder, LM | 2 |
| Tildon, JT | 3 |
| Stevenson, JH | 1 |
| Yeh, YY | 1 |
| Booth, RF | 1 |
| Clark, JB | 1 |
| Nehlig, A | 2 |
| Lehr, PR | 1 |
| Linz, DN | 1 |
| Garcia, VF | 1 |
| Arya, G | 1 |
| Hug, G | 1 |
| Tombragel, E | 1 |
| Landrigan, E | 1 |
| Chuck, G | 1 |
| Tsoras, M | 1 |
| Ryan, M | 1 |
| Ziegler, MM | 1 |
| Gatnau, R | 1 |
| Zimmerman, DR | 1 |
| Nissen, SL | 1 |
| Wannemuehler, M | 1 |
| Ewan, RC | 1 |
| Lean, IJ | 1 |
| Bruss, ML | 1 |
| Troutt, HF | 1 |
| Galland, JC | 1 |
| Farver, TB | 1 |
| Rostami, J | 1 |
| Holmberg, CA | 1 |
| Weaver, LD | 1 |
| Segués, T | 1 |
| Salvadó, J | 1 |
| Arola, L | 1 |
| Alemany, M | 1 |
| Rejman, JJ | 1 |
| Martin, KR | 2 |
| Bernard, JK | 1 |
| Tyberendt, TL | 1 |
| Adams, SH | 1 |
| Odle, J | 1 |
| Fleming, SE | 1 |
| Fitch, MD | 1 |
| Hudes, M | 1 |
| Dean, DJ | 1 |
| Cartee, GD | 1 |
| Mahagna, M | 1 |
| Nir, I | 1 |
| Barb, CR | 1 |
| Kraeling, RR | 1 |
| Rampacek, GB | 1 |
| Dove, CR | 1 |
| Chapman, IM | 1 |
| Hartman, ML | 1 |
| Pezzoli, SS | 1 |
| Harrell, FE | 1 |
| Hintz, RL | 1 |
| Alberti, KG | 1 |
| Thorner, MO | 1 |
| Krishnan, S | 1 |
| Ramakrishna, BS | 1 |
| Marker, JC | 1 |
| Clutter, WE | 1 |
| Cryer, PE | 1 |
| Bough, KJ | 2 |
| Valiyil, R | 1 |
| Han, FT | 1 |
| Eagles, DA | 2 |
| Chen, RS | 1 |
| Melendez, RI | 1 |
| Watkins, BA | 1 |
| Davis, RJ | 1 |
| Giesecke, D | 1 |
| Beck, U | 1 |
| Wiesmayr, S | 1 |
| Stangassinger, M | 1 |
| Davis, TA | 1 |
| Fiorotto, ML | 1 |
| Nguyen, HV | 1 |
| Burrin, DG | 1 |
| Reeds, PJ | 1 |
| Chugani, HT | 1 |
| Hovda, DA | 1 |
| Villablanca, JR | 1 |
| Phelps, ME | 1 |
| Xu, WF | 1 |
| Paolisso, G | 1 |
| Buonocore, S | 1 |
| Gentile, S | 1 |
| Sgambato, S | 1 |
| Varricchio, M | 1 |
| Scheen, A | 1 |
| D'Onofrio, F | 1 |
| Lefèbvre, PJ | 1 |
| Corbisier, P | 1 |
| Remacle, J | 1 |
| Ando, M | 1 |
| Itoh, T | 1 |
| Okuda, Y | 1 |
| Kawai, K | 1 |
| Yamashita, K | 1 |
| McKenna, MC | 1 |
| Bezold, LI | 1 |
| Kimatian, SJ | 1 |
| London, ED | 1 |
| Margolin, RA | 1 |
| Duara, R | 1 |
| Holloway, HW | 1 |
| Robertson-Tchabo, EA | 1 |
| Cutler, NR | 1 |
| Rapoport, SI | 1 |
| Pereira de Vasconcelos, A | 1 |
| Schroeder, H | 1 |
| Sapolsky, RM | 1 |
| Menon, NK | 1 |
| Lopez, RR | 1 |
| Lamers, KJ | 1 |
| Doesburg, WH | 1 |
| Gabreëls, FJ | 1 |
| Romsom, AC | 1 |
| Renier, WO | 1 |
| Wevers, RA | 1 |
| Lemmens, WA | 1 |
| Vömel, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Impact of Intermittent Fasting on Human Metabolism and Cell Autophagy[NCT02673515] | 60 participants (Actual) | Interventional | 2015-04-30 | Completed | |||
| Effect of Sodium-glucose Cotransporter-2 Inhibitor in Cellular Senescence in Patients With Cardiovascular Diseases or Advanced Type 2 Diabetes[NCT05975528] | Phase 4 | 87 participants (Anticipated) | Interventional | 2023-08-31 | Not yet recruiting | ||
| The Effect of Acipimox on GLP-1 Secretion in Healthy Subjects: a Pilot Study[NCT02796950] | 8 participants (Actual) | Interventional | 2016-06-30 | Completed | |||
| A Randomised Controlled Trial Evaluating the Efficacy and Mechanisms of a Ketogenic Diet as an Adjunctive Treatment for People With Treatment-resistant Depression[NCT06091163] | 100 participants (Anticipated) | Interventional | 2024-01-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"HOMA-Index was calculated by using the following formula:~HOMA-IR= FPG(mmol/l)*FSI (U/l)/22.5 FSI=fasting serum insulin FPG=fasting plasma glucose" (NCT02673515)
Timeframe: 4 weeks (from Baseline to 4 weeks)
| Intervention | no unit (Mean) |
|---|---|
| Alternate Day Fasting | 0.05 |
| Control Group | 0.06 |
ISI was calculated by using the following formula: ISI=0,222-0,00333 x BMI-0,0000779 x Ins120-0,000422 x age FSI=fasting serum insulin FPG=fasting plasma glucose (NCT02673515)
Timeframe: 4 weeks (from Baseline to 4 weeks)
| Intervention | no unit (Median) |
|---|---|
| Alternate Day Fasting | 0 |
| Control Group | 0 |
"Matsuda index was calculated by using the following formula:~Matsuda-Index = 10000√(FPG∗FSI)∗(mean glucose*mean insulin) FSI=fasting serum insulin FPG=fasting plasma glucose" (NCT02673515)
Timeframe: 4 weeks (from Baseline to 4 weeks)
| Intervention | no unit (Median) |
|---|---|
| Alternate Day Fasting | -0.4 |
| Control Group | -0.7 |
QUICKI was calculated by using the following formula: QUICKI= log(FSI)+log (FPG) FSI=fasting serum insulin FPG=fasting plasma glucose (NCT02673515)
Timeframe: 4 weeks (from Baseline to 4 weeks)
| Intervention | no unit (Median) |
|---|---|
| Alternate Day Fasting | 0 |
| Control Group | 0 |
Change of blood pressure from Baseline to 4 weeks (NCT02673515)
Timeframe: 4 weeks
| Intervention | mmHg (Median) | |
|---|---|---|
| Systolic blood pressure | Diastolic blood pressure | |
| Alternate Day Fasting | -4.5 | -2.5 |
| Control Group | -1 | 0 |
6 reviews available for 3-hydroxybutyric acid and Aging
| Article | Year |
|---|---|
β-hydroxybutyrate as an Anti-Aging Metabolite.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Antioxidants; Biomarkers; Disease Susceptibility; Energy Meta | 2021 |
The Aging Metabolome-Biomarkers to Hub Metabolites.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Biomarkers; Citric Acid Cycle; DNA Damage; Epigenesis, Geneti | 2020 |
β-hydroxybutyrate and its metabolic effects on age-associated pathology.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Disease Susceptibility; Humans; Lipid Metabolism; Skin Aging | 2020 |
Beneficial Effects of Exogenous Ketogenic Supplements on Aging Processes and Age-Related Neurodegenerative Diseases.
Topics: 3-Hydroxybutyric Acid; Aging; Alzheimer Disease; Diet, Ketogenic; Dietary Supplements; Epigenomics; | 2021 |
β-Hydroxybutyrate: A Signaling Metabolite.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Epigenesis, Genetic; Humans; Liver; Signal Transduction; Star | 2017 |
Ketone bodies as signaling metabolites.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Caloric Restriction; Histone Deacetylase Inhibitors; Histone | 2014 |
4 trials available for 3-hydroxybutyric acid and Aging
| Article | Year |
|---|---|
Alternate Day Fasting Improves Physiological and Molecular Markers of Aging in Healthy, Non-obese Humans.
Topics: 3-Hydroxybutyric Acid; Adult; Aging; Biomarkers; Body Mass Index; Caloric Restriction; Energy Intake | 2019 |
Age-related metabolic changes of pre-weaned Simmental calves fed whole bulk milk and ad libitum calf starter.
Topics: 3-Hydroxybutyric Acid; Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Biom | 2021 |
Metabolic response to a ketogenic breakfast in the healthy elderly.
Topics: 3-Hydroxybutyric Acid; Acetone; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Apolipoprotein E4 | 2009 |
Bovine ketosis and somatotrophin: risk factors for ketosis and effects of ketosis on health and production.
Topics: 3-Hydroxybutyric Acid; Aging; Analysis of Variance; Animals; Blood Glucose; Body Weight; Cattle; Cat | 1994 |
54 other studies available for 3-hydroxybutyric acid and Aging
| Article | Year |
|---|---|
Urinary ketone body loss leads to degeneration of brain white matter in elderly SLC5A8-deficient mice.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Glucose; Ketone Bodies; Kidney; Leukoencephalopathies; Male; | 2020 |
Anti-Aging Effect of the Ketone Metabolite β-Hydroxybutyrate in
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Centrosome; DNA Damage; Drosophila melanogaster; Heterochroma | 2020 |
Anti-inflammatory action of β-hydroxybutyrate via modulation of PGC-1α and FoxO1, mimicking calorie restriction.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Anti-Inflammatory Agents; Caloric Restriction; Gene Expressio | 2019 |
D-ß-hydroxybutyrate: an anti-aging ketone body.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Caenorhabditis elegans; Humans; Ketone Bodies; Mice | 2015 |
1'-Acetoxychavicol acetate ameliorates age-related spatial memory deterioration by increasing serum ketone body production as a complementary energy source for neuronal cells.
Topics: 3-Hydroxybutyric Acid; Aging; Alpinia; Animals; Benzyl Alcohols; Energy Metabolism; Hippocampus; Ket | 2016 |
Metabolic blood profile of beef heifers during oestrous and non-oestrous states.
Topics: 3-Hydroxybutyric Acid; Adipose Tissue; Aging; Alkaline Phosphatase; Animals; Aspartate Aminotransfer | 2016 |
Induction of ketosis may improve mitochondrial function and decrease steady-state amyloid-beta precursor protein (APP) levels in the aged dog.
Topics: 3-Hydroxybutyric Acid; Aging; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precurs | 2008 |
Ketogenic diets cause opposing changes in synaptic morphology in CA1 hippocampus and dentate gyrus of late-adult rats.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Body Weight; Brain-Derived Neurotrophic Factor; Dentate Gyrus | 2008 |
Eicosapentaenoic acid decreases postprandial beta-hydroxybutyrate and free fatty acid responses in healthy young and elderly.
Topics: 3-Hydroxybutyric Acid; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Area Under Curve; Blood Gl | 2009 |
A ketogenic diet increases succinic dehydrogenase activity in aging cardiomyocytes.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Diet, Ketogenic; Male; Microscopy, Electron; Mitochondria, He | 2009 |
Rumen development and growth of Balouchi lambs offered alfalfa hay pre- and post-weaning.
Topics: 3-Hydroxybutyric Acid; Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Diet | 2011 |
Ketogenic diet increases concentrations of kynurenic acid in discrete brain structures of young and adult rats.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Blood Glucose; Brain Chemistry; Cerebral Cortex; Corpus Stria | 2012 |
Effects of 2-mercaptoacetate on ingestive behavior in 18- and 21-day-old rats.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Suckling; Blood Glucose; Body Weight; Diet; Dose-Res | 2002 |
Influence of age and caloric restriction on liver glycolytic enzyme activities and metabolite concentrations in mice.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Caloric Restriction; Fructosediphosphates; Glu | 2003 |
High beta-hydroxybutyrate concentration in liver and skeletal muscle of newly hatched chicks.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Newborn; Chickens; Ketone Bodies; Liver; Liver Extra | 2003 |
Developmental switch in brain nutrient transporter expression in the rat.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Blood Glucose; Blood-Brain Barrier; Brain; Brain Chemistry; C | 2003 |
Changing metabolic and energy profiles in fetal, neonatal, and adult rat brain.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Aging; Animals; Animals, Newborn; Blood Glucose; Brai | 2003 |
Effect of various levels of forage and form of diet on rumen development and growth in calves.
Topics: 3-Hydroxybutyric Acid; Aging; Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Catt | 2004 |
Studies of cerebral beta-hydroxybutyrate transport by carotid injection; effects of age, diet and injectant composition.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Blood-Brain Barrier; Capillary Permeability; Dietary Fats; El | 1983 |
Antiketonemic effect of glycerol during development of the rat.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Animals, Newborn; Animals, Suckling; Blood Glu | 1982 |
Antiketonemic and antiketogenic actions of carnitine in vivo and in vitro in rats.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Carnitine; Coenzyme A; Corn Oil; Dietary Fats; | 1981 |
Energy metabolism in rat brain: inhibition of pyruvate decarboxylation by 3-hydroxybutyrate in neonatal mitochondria.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Newborn; Brain; Female; Hydroxybutyrates; Male; Mito | 1981 |
Glucose and 3-hydroxybutyrate utilization by chick telencephalon during postnatal development.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Blood-Brain Barrier; Chickens; Glucose; Hydroxybutyrates; Kin | 1981 |
Weanling and adult rats differ in fatty acid and carnitine metabolism during sepsis.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Bacterial Infections; Blood Glucose; Carnitine; Fatty Acids; | 1995 |
Effects of excess dietary leucine and leucine catabolites on growth and immune responses in weanling pigs.
Topics: 3-Hydroxybutyric Acid; Aging; Amino Acids; Animals; Avena; Blood Urea Nitrogen; Crosses, Genetic; De | 1995 |
Long-term effects of cafeteria diet feeding on young Wistar rats.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Blood Glucose; Body Weight; Diet; Female; Glycerol; Hydroxybu | 1994 |
Response of peripheral blood mononuclear cells to mitogenic stimulation in young calves.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Newborn; Blood Glucose; Cattle; Hydroxybutyrates; Le | 1994 |
Intake, growth, and selected blood parameters in calves fed calf starter via bucket or bottle.
Topics: 3-Hydroxybutyric Acid; Aging; Animal Feed; Animals; Blood Glucose; Blood Urea Nitrogen; Bottle Feedi | 1994 |
Plasma beta-hydroxybutyrate after octanoate challenge: attenuated ketogenic capacity in neonatal swine.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Newborn; Caprylates; Hydroxybutyrates; Ketone Bodies | 1993 |
Intestinal cell respiration is influenced by animal age, strain, and feeding status.
Topics: 3-Hydroxybutyric Acid; Acetates; Aging; Animals; Butyrates; Cells, Cultured; Colon; Fasting; Food; G | 1994 |
Brief dietary restriction increases skeletal muscle glucose transport in old Fischer 344 rats.
Topics: 3-Hydroxybutyric Acid; 3-O-Methylglucose; Aging; Animals; Biological Transport; Body Weight; Diet; F | 1996 |
Comparative development of digestive organs, intestinal disaccharidases and some blood metabolites in broiler and layer-type chicks after hatching.
Topics: 3-Hydroxybutyric Acid; Aging; Alkaline Phosphatase; alpha-Amylases; alpha-Glucosidases; Analysis of | 1996 |
Metabolic changes during the transition from the fed to the acute feed-deprived state in prepuberal and mature gilts.
Topics: 3-Hydroxybutyric Acid; Aging; Amino Acids, Essential; Animals; Blood Glucose; Eating; Fatty Acids, N | 1997 |
Effect of aging on the sensitivity of growth hormone secretion to insulin-like growth factor-I negative feedback.
Topics: 3-Hydroxybutyric Acid; Adult; Aging; Blood Glucose; Dose-Response Relationship, Drug; Fatty Acids, N | 1997 |
Butyrate and glucose metabolism in isolated colonocytes in the developing rat colon.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Animals, Newborn; Butyrates; Butyric Acid; Car | 1998 |
Reduced epinephrine clearance and glycemic sensitivity to epinephrine in older individuals.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Aging; Alanine; Blood Glucose; Blood Pressure; Epinephrine; Fatt | 1998 |
Seizure resistance is dependent upon age and calorie restriction in rats fed a ketogenic diet.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Behavior, Animal; Convulsants; Diet; Energy Intake; Growth; K | 1999 |
Path analysis shows that increasing ketogenic ratio, but not beta-hydroxybutyrate, elevates seizure threshold in the Rat.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Body Weight; Convulsants; Diet; Differential Threshold; Disea | 1999 |
Metabolic and behavioral responses in pre-weanling rats following alteration of maternal diet.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Newborn; Behavior, Animal; Blood Glucose; Diet; Diet | 2001 |
The effect of rumen epithelial development on metabolic activities and ketogenesis by the tissue in vitro.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Butyrates; Butyric Acid; Epithelium; Glucose; | 1979 |
Response of muscle protein synthesis to fasting in suckling and weaned rats.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Suckling; Blood Glucose; Fasting; Hydroxybutyrates; | 1991 |
Metabolic maturation of the brain: a study of local cerebral glucose utilization in the developing cat.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Newborn; Autoradiography; Blood Glucose; Brain; Cats | 1991 |
Pulsatile glucagon has greater hyperglycaemic, lipolytic and ketogenic effects than continuous hormone delivery in man: effect of age.
Topics: 3-Hydroxybutyric Acid; Adult; Age Factors; Aged; Aging; Blood Glucose; C-Peptide; Drug Administratio | 1990 |
Involvement of mitochondria in cell degeneration.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Cell Division; Cell Fractionation; Cell Line; Cell Survival; | 1990 |
Changes of amino acid by the deprivation of energy sources in the cerebral cortex.
Topics: 3-Hydroxybutyric Acid; Aging; Amino Acids; Animals; Cerebral Cortex; Energy Metabolism; Female; Hydr | 1989 |
Age-related change in ketone body metabolism: diminished glucagon effect on ketogenesis in adult rats.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Animals; Carnitine; Cyclic AMP; Diabetes Mellitus, Expe | 1987 |
Competition of glycerol with other oxidizable substrates in rat brain.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Brain; Carbon Dioxide; Female; Glucose; Glutamine; Glycerol; | 1986 |
Transport of 3-hydroxy[3-14C]butyrate by dissociated cells from rat brain.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Biological Transport; Brain; Hydrogen-Ion Concentration; Hydr | 1988 |
Effects of fasting on ketone body concentrations in healthy men of different ages.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Aging; Brain; Fasting; Glucose; Humans; Hydroxybu | 1986 |
Effects of early chronic phenobarbital treatment on the maturation of energy metabolism in the developing rat brain. II. Incorporation of beta-hydroxybutyrate into amino acids.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Amino Acids; Animals; Animals, Newborn; Cerebellum; Cer | 1987 |
Glucocorticoid toxicity in the hippocampus: reversal by supplementation with brain fuels.
Topics: 3-Hydroxybutyric Acid; Adrenalectomy; Aging; Animals; Cell Survival; Corticosterone; Drug Synergism; | 1986 |
The effects of mild congenital methylmercury intoxication on the metabolism of 3-hydroxybutyrate and glucose in the brains of suckling rats.
Topics: 3-Hydroxybutyric Acid; Aging; Animals; Animals, Suckling; Body Weight; Brain; Female; Glucose; Hydro | 1985 |
Reference values of blood components related to fuel metabolism in children after an overnight fast.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adolescent; Aging; Alanine; Blood Glucose; Child; Child, Presc | 1985 |
Age-dependent changes of biochemical parameters during the perfusion of the isolated rat liver.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Aging; Alanine Transaminase; Animals; Aspartate Aminotransfera | 1985 |