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3-hydroxybutyric acid and Aging, Premature

3-hydroxybutyric acid has been researched along with Aging, Premature in 1 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Aging, Premature: Changes in the organism associated with senescence, occurring at an accelerated rate.

Research Excerpts

ExcerptRelevanceReference
"Furthermore, premature aging in CS mice, nematodes, and human cells results from aberrant PARP activation due to deficient DNA repair leading to decreased SIRT1 activity and mitochondrial dysfunction."5.40A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome. ( Bergersen, LH; Bohr, VA; Cogger, VC; Croteau, DL; de Cabo, R; Dunn, CA; Fang, EF; Hasan-Olive, MM; Iyama, T; Le Couteur, DG; Mangerich, A; Mattson, MP; Mitchell, SJ; Moaddel, R; Scheibye-Knudsen, M; Singh, N; Veith, S; Wang, J; Ward, T; Warren, A; Wilson, DM; Wilson, MA, 2014)
"Furthermore, premature aging in CS mice, nematodes, and human cells results from aberrant PARP activation due to deficient DNA repair leading to decreased SIRT1 activity and mitochondrial dysfunction."1.40A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome. ( Bergersen, LH; Bohr, VA; Cogger, VC; Croteau, DL; de Cabo, R; Dunn, CA; Fang, EF; Hasan-Olive, MM; Iyama, T; Le Couteur, DG; Mangerich, A; Mattson, MP; Mitchell, SJ; Moaddel, R; Scheibye-Knudsen, M; Singh, N; Veith, S; Wang, J; Ward, T; Warren, A; Wilson, DM; Wilson, MA, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Scheibye-Knudsen, M1
Mitchell, SJ1
Fang, EF1
Iyama, T1
Ward, T1
Wang, J1
Dunn, CA1
Singh, N1
Veith, S1
Hasan-Olive, MM1
Mangerich, A1
Wilson, MA1
Mattson, MP1
Bergersen, LH1
Cogger, VC1
Warren, A1
Le Couteur, DG1
Moaddel, R1
Wilson, DM1
Croteau, DL1
de Cabo, R1
Bohr, VA1

Other Studies

1 other study available for 3-hydroxybutyric acid and Aging, Premature

ArticleYear
A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndrome.
    Cell metabolism, 2014, Nov-04, Volume: 20, Issue:5

    Topics: 3-Hydroxybutyric Acid; Aging, Premature; Animals; Cell Line; Cockayne Syndrome; Diet, High-Fat; Enzy

2014