Page last updated: 2024-10-17

3-hydroxybutyric acid and Adult Spinal Muscular Atrophy

3-hydroxybutyric acid has been researched along with Adult Spinal Muscular Atrophy in 1 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Research Excerpts

ExcerptRelevanceReference
"Proximal spinal muscular atrophy (SMA) is a leading genetic cause of infant death."1.36Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy. ( Butchbach, ME; Lorson, CL; Marston, J; McCrone, JT; Rhoades, S; Rose, FF; Sinnott, R, 2010)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Butchbach, ME1
Rose, FF1
Rhoades, S1
Marston, J1
McCrone, JT1
Sinnott, R1
Lorson, CL1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Prospective Evaluation of Infants With Spinal Muscular Atrophy: SPOT SMA[NCT02831296]1,000 participants (Anticipated)Observational [Patient Registry]2016-02-29Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for 3-hydroxybutyric acid and Adult Spinal Muscular Atrophy

ArticleYear
Effect of diet on the survival and phenotype of a mouse model for spinal muscular atrophy.
    Biochemical and biophysical research communications, 2010, Jan-01, Volume: 391, Issue:1

    Topics: 3-Hydroxybutyric Acid; Animals; Blood Glucose; Diet; Disease Models, Animal; Female; Male; Mice; Mic

2010