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3-hydroxybutyric acid and Acute Kidney Injury

3-hydroxybutyric acid has been researched along with Acute Kidney Injury in 8 studies

3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.

Acute Kidney Injury: Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.

Research Excerpts

ExcerptRelevanceReference
"Sepsis is a major cause of acute kidney injury (AKI)."1.91β-hydroxybutyrate ameliorates sepsis-induced acute kidney injury. ( Kim, IY; Kim, MJ; Kim, SR; Kim, YS; Lee, DW; Lee, SB, 2023)
" A plasma glucose level of 300 mg dl-1 was not achieved until the total dosage of insulin amounted to 91,580 units at hour 25."1.28Transient extreme insulin resistance in shock during diabetic ketoacidosis. ( Hasumi, S; Omori, Y; Shimizu, Y; Wasada, T; Yokoyama, H; Yoshino, H, 1992)
"Marked dehydration is thought to cause renal dysfunction, and the increase in ADH may have helped to prevent further aggravation of ketoacidosis."1.28A case of diabetic non-ketotic hyperosmolar coma with an increase with plasma 3-hydroxybutyrate. ( Harano, Y; Kinoshita, O; Kojima, H; Masuda, I; Matsuyama, T; Nishioeda, Y; Suzuki, M; Tsushima, M, 1991)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (25.00)18.2507
2000's1 (12.50)29.6817
2010's3 (37.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Luo, S1
Yang, M1
Han, Y1
Zhao, H1
Jiang, N1
Li, L1
Chen, W1
Li, C1
Yang, J1
Liu, Y1
Liu, C1
Zhao, C1
Sun, L1
Kim, MJ1
Kim, YS1
Kim, SR1
Lee, DW1
Lee, SB1
Kim, IY1
Perry, HM1
Huang, L1
Wilson, RJ1
Bajwa, A1
Sesaki, H1
Yan, Z1
Rosin, DL1
Kashatus, DF1
Okusa, MD1
Wei, T1
Tian, W1
Liu, F1
Xie, G1
Tran, MT1
Zsengeller, ZK1
Berg, AH1
Khankin, EV1
Bhasin, MK1
Kim, W1
Clish, CB1
Stillman, IE1
Karumanchi, SA1
Rhee, EP1
Parikh, SM1
Clemmesen, JO1
Høy, CE1
Kondrup, J1
Ott, P1
Yokoyama, H1
Wasada, T1
Shimizu, Y1
Yoshino, H1
Hasumi, S1
Omori, Y1
Kinoshita, O1
Masuda, I1
Suzuki, M1
Tsushima, M1
Nishioeda, Y1
Matsuyama, T1
Kojima, H1
Harano, Y1

Other Studies

8 other studies available for 3-hydroxybutyric acid and Acute Kidney Injury

ArticleYear
β-Hydroxybutyrate against Cisplatin-Induced acute kidney injury via inhibiting NLRP3 inflammasome and oxidative stress.
    International immunopharmacology, 2022, Volume: 111

    Topics: 3-Hydroxybutyric Acid; Acute Kidney Injury; Animals; Cisplatin; Humans; Inflammasomes; Interleukin-1

2022
β-hydroxybutyrate ameliorates sepsis-induced acute kidney injury.
    Molecular biology reports, 2023, Volume: 50, Issue:11

    Topics: 3-Hydroxybutyric Acid; Acute Kidney Injury; Animals; Apoptosis; Kidney; Lipopolysaccharides; Male; M

2023
Dynamin-Related Protein 1 Deficiency Promotes Recovery from AKI.
    Journal of the American Society of Nephrology : JASN, 2018, Volume: 29, Issue:1

    Topics: 3-Hydroxybutyric Acid; Acute Kidney Injury; Animals; Apoptosis; Disease Progression; Dynamins; Fibro

2018
Protective effects of exogenous β-hydroxybutyrate on paraquat toxicity in rat kidney.
    Biochemical and biophysical research communications, 2014, May-16, Volume: 447, Issue:4

    Topics: 3-Hydroxybutyric Acid; Acute Kidney Injury; Animals; Apoptosis; bcl-2-Associated X Protein; Blood Ur

2014
PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection.
    Nature, 2016, Mar-24, Volume: 531, Issue:7595

    Topics: 3-Hydroxybutyric Acid; Acute Kidney Injury; Adipose Tissue; Amino Acids; Animals; Cytokines; Dinopro

2016
Splanchnic metabolism of fuel substrates in acute liver failure.
    Journal of hepatology, 2000, Volume: 33, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acute Kidney Injury; Adult; Blood Glucose; Female; Hepatic Enc

2000
Transient extreme insulin resistance in shock during diabetic ketoacidosis.
    Endocrinologia japonica, 1992, Volume: 39, Issue:6

    Topics: 3-Hydroxybutyric Acid; Acute Kidney Injury; Aged; Blood Glucose; Diabetic Ketoacidosis; Erythrocytes

1992
A case of diabetic non-ketotic hyperosmolar coma with an increase with plasma 3-hydroxybutyrate.
    Endocrinologia japonica, 1991, Volume: 38, Issue:5

    Topics: 3-Hydroxybutyric Acid; Acute Kidney Injury; Aged; Aged, 80 and over; Blood Chemical Analysis; Blood

1991