3-hydroxybutyric acid has been researched along with Acute Brain Injuries in 11 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ischemic stroke is a leading cause of disability worldwide." | 1.91 | Modulation of the autophagy-lysosomal pathway and endoplasmic reticulum stress by ketone bodies in experimental models of stroke. ( Bernal-Vicente, BN; Gerónimo-Olvera, C; Gómora-García, JC; Heras-Romero, Y; Massieu, L; Montiel, T; Pérez-Martínez, X; Tovar-Y-Romo, LB, 2023) |
| "Hypoglycemia has emerged as a prominent complication in anti-diabetic drug therapy or negative energy balance of animals, which causes brain damage, cognitive impairment, and even death." | 1.72 | β-Hydroxybutyrate Alleviates Low Glucose-Induced Apoptosis via Modulation of ROS-Mediated p38 MAPK Signaling. ( Chai, X; Huang, J; Li, C; Pan, J; Wu, Y; Xue, Y; Yang, J; Zhao, S; Zhou, W; Zhu, X, 2022) |
| "Rats fed a KD had a higher seizure threshold (longer latency to flurothyl-induced seizure activity) than rats fed a standard diet (SD); this effect was seen when KD was in place at the time of seizure testing (3 and 6 weeks following FPI), but was absent when KD had been replaced by SD at time of testing." | 1.36 | Does ketogenic diet alter seizure sensitivity and cell loss following fluid percussion injury? ( Campos, L; Delance, A; Lyeth, BG; Nguyen, DV; Poon, CC; Schwartzkroin, PA; Van, KC; Wenzel, HJ, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 5 (45.45) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Li, C | 1 |
| Chai, X | 1 |
| Pan, J | 1 |
| Huang, J | 1 |
| Wu, Y | 1 |
| Xue, Y | 1 |
| Zhou, W | 1 |
| Yang, J | 1 |
| Zhu, X | 1 |
| Zhao, S | 1 |
| Cascant-Vilaplana, MM | 1 |
| Lara-Cantón, I | 1 |
| Núñez-Ramiro, A | 1 |
| Solaz-García, Á | 1 |
| Llorens-Salvador, R | 1 |
| Quintás, G | 1 |
| Kuligowski, J | 1 |
| Vento, M | 1 |
| Montiel, T | 2 |
| Gómora-García, JC | 1 |
| Gerónimo-Olvera, C | 2 |
| Heras-Romero, Y | 1 |
| Bernal-Vicente, BN | 1 |
| Pérez-Martínez, X | 1 |
| Tovar-Y-Romo, LB | 1 |
| Massieu, L | 2 |
| Boruczkowski, D | 1 |
| Pujal, JM | 1 |
| Zdolińska-Malinowska, I | 1 |
| Julio-Amilpas, A | 1 |
| Soto-Tinoco, E | 1 |
| White, H | 1 |
| Venkatesh, B | 1 |
| Jones, M | 1 |
| Fuentes, H | 1 |
| Hu, ZG | 1 |
| Wang, HD | 1 |
| Jin, W | 1 |
| Yin, HX | 1 |
| Schwartzkroin, PA | 1 |
| Wenzel, HJ | 1 |
| Lyeth, BG | 1 |
| Poon, CC | 1 |
| Delance, A | 1 |
| Van, KC | 1 |
| Campos, L | 1 |
| Nguyen, DV | 1 |
| Deng-Bryant, Y | 1 |
| Prins, ML | 2 |
| Hovda, DA | 2 |
| Harris, NG | 1 |
| Lee, SM | 1 |
| Fujima, LS | 1 |
| Robertson, CS | 1 |
| Goodman, JC | 1 |
| Narayan, RK | 1 |
| Contant, CF | 1 |
| Grossman, RG | 1 |
1 review available for 3-hydroxybutyric acid and Acute Brain Injuries
| Article | Year |
|---|---|
Autologous cord blood in children with cerebral palsy: a review.
Topics: 3-Hydroxybutyric Acid; Amino Acids; Animals; Brain Diseases; Brain Injuries; Carnitine; Cerebral Pal | 2019 |
1 trial available for 3-hydroxybutyric acid and Acute Brain Injuries
| Article | Year |
|---|---|
The effect of glucose administration on carbohydrate metabolism after head injury.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Blood Glucose; Brain Injuries; Carbohydrate Metab | 1991 |
9 other studies available for 3-hydroxybutyric acid and Acute Brain Injuries
| Article | Year |
|---|---|
β-Hydroxybutyrate Alleviates Low Glucose-Induced Apoptosis via Modulation of ROS-Mediated p38 MAPK Signaling.
Topics: 3-Hydroxybutyric Acid; Animals; Apoptosis; Brain Injuries; Caspase 3; Glucose; Hypoglycemia; NF-kapp | 2022 |
Longitudinal perturbations of plasma nuclear magnetic resonance profiles in neonatal encephalopathy.
Topics: 3-Hydroxybutyric Acid; Biomarkers; Brain Injuries; Humans; Hypothermia, Induced; Hypoxia-Ischemia, B | 2023 |
Modulation of the autophagy-lysosomal pathway and endoplasmic reticulum stress by ketone bodies in experimental models of stroke.
Topics: 3-Hydroxybutyric Acid; Animals; Autophagy; Brain Injuries; Endoplasmic Reticulum Stress; Endoribonuc | 2023 |
Protection of hypoglycemia-induced neuronal death by β-hydroxybutyrate involves the preservation of energy levels and decreased production of reactive oxygen species.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adenosine Triphosphate; Animals; Brain Injuries; Brain Ischemi | 2015 |
Serial changes in plasma ketone concentrations in patients with acute brain injury.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Adult; Aged; Brain Injuries; Female; Glasgow Coma Scale; Human | 2017 |
Ketogenic diet reduces cytochrome c release and cellular apoptosis following traumatic brain injury in juvenile rats.
Topics: 3-Hydroxybutyric Acid; Animals; Apoptosis; Blood Glucose; Brain; Brain Injuries; Caspase 3; Cytochro | 2009 |
Does ketogenic diet alter seizure sensitivity and cell loss following fluid percussion injury?
Topics: 3-Hydroxybutyric Acid; Animals; Brain Injuries; CD11b Antigen; Cell Count; Cell Death; Diet, Ketogen | 2010 |
Ketogenic diet prevents alterations in brain metabolism in young but not adult rats after traumatic brain injury.
Topics: 3-Hydroxybutyric Acid; Age Factors; Amino Acids; Animals; Aspartic Acid; Brain; Brain Injuries; Diet | 2011 |
Increased cerebral uptake and oxidation of exogenous betaHB improves ATP following traumatic brain injury in adult rats.
Topics: 3-Hydroxybutyric Acid; Adenosine Triphosphate; Animals; Brain; Brain Injuries; Carbon Dioxide; Carbo | 2004 |