3-hydroxybutyric acid has been researched along with Acidosis in 77 studies
3-Hydroxybutyric Acid: BUTYRIC ACID substituted in the beta or 3 position. It is one of the ketone bodies produced in the liver.
3-hydroxybutyric acid : A straight-chain 3-hydroxy monocarboxylic acid comprising a butyric acid core with a single hydroxy substituent in the 3- position; a ketone body whose levels are raised during ketosis, used as an energy source by the brain during fasting in humans. Also used to synthesise biodegradable plastics.
Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acute metabolic acidosis associated with accumulation of lactate has been previously reported in isoniazid (INH) intoxication." | 7.67 | Association of beta hydroxybutyric acidosis with isoniazid intoxication. ( Maksy, M; Nathan, R; Ness, R; Pahl, MV; Vaziri, ND, 1984) |
| "To determine the effects of acute metabolic acidosis and alkalosis on leucine metabolism in vivo, mongrel dogs were infused with [1-14C]leucine for 8 h, along with NaCl, HCI, or NaHCO3 over the last 4 h." | 7.67 | Effects of acute metabolic acidosis and alkalosis on leucine metabolism in conscious dogs. ( Haymond, MW; Miles, JM; Rodriguez, NR; Schwenk, WF, 1989) |
| "We administered dichloroacetate, which prevents or reverses hyperlactatemia in animals and lowers plasma lactate levels in human beings, to 13 patients with lactic acidosis of various causes." | 7.66 | Treatment of lactic acidosis with dichloroacetate. ( Baumgartner, TG; Curry, SH; Harman, EM; Misbin, RI; Stacpoole, PW, 1983) |
| "Acute acidosis was induced in sheep, and gastrointestinal permeability was assessed by using lactulose as a permeability marker." | 5.19 | Experimental acute rumen acidosis in sheep: consequences on clinical, rumen, and gastrointestinal permeability conditions and blood chemistry. ( Ahmed, S; Bani, P; Bertoni, G; Jahan, N; Minuti, A; Piccioli-Cappelli, F; Trevisi, E, 2014) |
| " A variety of conditions preceded the onset of acidosis, and all had taken acetaminophen (paracetamol), although in therapeutic amounts in most subjects." | 3.70 | Transient 5-oxoprolinuria and high anion gap metabolic acidosis: clinical and biochemical findings in eleven subjects. ( Hauser, S; Pitt, JJ, 1998) |
| "Acute metabolic acidosis associated with accumulation of lactate has been previously reported in isoniazid (INH) intoxication." | 3.67 | Association of beta hydroxybutyric acidosis with isoniazid intoxication. ( Maksy, M; Nathan, R; Ness, R; Pahl, MV; Vaziri, ND, 1984) |
| "To determine the effects of acute metabolic acidosis and alkalosis on leucine metabolism in vivo, mongrel dogs were infused with [1-14C]leucine for 8 h, along with NaCl, HCI, or NaHCO3 over the last 4 h." | 3.67 | Effects of acute metabolic acidosis and alkalosis on leucine metabolism in conscious dogs. ( Haymond, MW; Miles, JM; Rodriguez, NR; Schwenk, WF, 1989) |
| " To test the role of beta-hydroxybutyric acid (BHB) and acidosis in generating such changes, we studied the pituitary-thyroid axis of streptozotocin-diabetic rats, BHB or ammonium chloride (NH4Cl)-treated normal rats." | 3.67 | Effects of diabetes, beta-hydroxybutyric acid and metabolic acidosis on the pituitary-thyroid axis in the rat. ( Boado, R; Colombo, O; Zaninovich, AA, 1985) |
| " Fasting was associated with a compensated (no change in pH) mild metabolic acidosis but no change in plasma insulin and glucagon or blood glutamine." | 3.67 | Glutamine blocks lipolysis and ketogenesis of fasting. ( Abumrad, N; Cersosimo, E; Hoxworth, B; Lacy, W; Williams, P, 1986) |
| "We administered dichloroacetate, which prevents or reverses hyperlactatemia in animals and lowers plasma lactate levels in human beings, to 13 patients with lactic acidosis of various causes." | 3.66 | Treatment of lactic acidosis with dichloroacetate. ( Baumgartner, TG; Curry, SH; Harman, EM; Misbin, RI; Stacpoole, PW, 1983) |
| "Alcoholic ketoacidosis (AKA) is an important and probably underdiagnosed differential diagnosis for metabolic acidosis with an increased anion gap." | 2.38 | [Alcoholic ketoacidosis]. ( Caspar, CB; Iten, PX; Jost, R; Risti, B; Russi, EW; Speich, R, 1993) |
| "Euglycemic diabetic ketoacidosis is a metabolic condition characterized by relative euglycemia, ketonemia, and metabolic acidosis that occurs through mechanisms resembling starvation." | 1.91 | Euglycemic diabetic ketoacidosis (EDKA) after pancreaticoduodenectomy: An under-recognized metabolic abnormality with outcome implications. ( Bowne, WB; Kavanagh, TR; Krampitz, GW; Lavu, H; Nevler, A; Rshaidat, H; Sholevar, C; Swaminathan, V; Torjani, A; Xiao, K; Yeo, CJ; Yudkoff, C, 2023) |
| "Diabetic ketoalkalosis is a common yet easily overlooked alkalemic variant of DKA associated with mixed acid-base disorders, and a high proportion of these presentations have severe ketoacidosis and thus, require the same treatment as traditional DKA." | 1.91 | Diabetic Ketoalkalosis: A Common Yet Easily Overlooked Alkalemic Variant of Diabetic Ketoacidosis Associated with Mixed Acid-Base Disorders. ( Cao, S, 2023) |
| "The diagnosis of alcoholic ketoacidosis (AKA) has traditionally been made based only on clinical history and the presence of severe metabolic acidosis with a high anion gap (AG); however, the concentration of beta-hydroxybutyrate (BOHB), a pivotal ketone body in AKA, is not evaluated in most cases." | 1.91 | Alcoholic ketoacidosis evaluated with a point-of-care capillary beta-hydroxybutyrate measurement device. ( Matsumoto, T; Nishizawa, T; Sasano, M; Todaka, T, 2023) |
| "Diabetic ketoacidosis is defined as hyperglycemia >250 mg/dL with metabolic acidosis of arterial pH <7." | 1.51 | Ketoacidosis in Euglycemic Patients With Type 2 Diabetes After Abdominal Surgery. ( Bennett, A; Geehan, D; Moncure, M; Segebrecht, R; Van Way, CW; Weide, L, 2019) |
| "Severe falciparum malaria is commonly complicated by metabolic acidosis." | 1.42 | The role of previously unmeasured organic acids in the pathogenesis of severe malaria. ( Charunwatthana, P; Chotinavich, K; Day, NP; Dondorp, AM; Douthwaite, S; Faiz, MA; Ghose, A; Hassan, MM; Herdman, MT; Hossain, MA; Kingston, HW; Leepipatpiboon, N; Leopold, SJ; Maude, RJ; Mishra, S; Mohanty, S; Plewes, K; Silamut, K; Sriboonvorakul, N; Tarning, J; White, NJ; Woodrow, CJ, 2015) |
| "Alcoholic, starvation, and severe diabetic ketoacidosis (AKA, SKA, and DKA, respectively) may produce beta-hydroxybutyrate (BOHB) in marked excess of acetone (ACET) and acetoacetate (AcAc)." | 1.35 | Bedside detection of urine beta-hydroxybutyrate in diagnosing metabolic acidosis. ( Hoffman, RS; Manini, AF; Smith, SW; Szekely, T, 2008) |
| "Metabolic acidosis is associated with most severe malaria deaths in African children, and most deaths occur before maximum antimalarial action is achieved." | 1.33 | Characterisation of metabolic acidosis in Kenyan children admitted to hospital for acute non-surgical conditions. ( Berkley, J; English, M; Kokwaro, G; Lowe, B; Mwakesi, R; Sasi, P; Shebe, M, 2006) |
| "Louis Animal Emergency Clinic South for treatment of enteritis caused by parvovirus infection were used in our study." | 1.31 | Determination of serum organic acids in puppies with naturally acquired parvoviral enteritis. ( Dunphy, E; Mann, FA; Nappert, G; Ruben, D, 2002) |
| "Post-exercise ketosis is known to be suppressed by physical training and by a high carbohydrate diet." | 1.28 | Post-exercise ketosis and the glycogen content of liver and muscle in rats on a high carbohydrate diet. ( Adams, JH; Koeslag, JH, 1989) |
| "Metoclopramide has previously been shown to inhibit the ketosis of starvation in rats and humans." | 1.28 | D2-dopaminergic blockade does not influence post-exercise ketosis in non-athletes. ( Koeslag, JH; Lochner, JV; Vahed, YA, 1989) |
| "Propionic acid was used as a possible preventive agent against ketogenesis." | 1.27 | Effect of propionic acid on ketogenesis in lactating sheep fed restricted rations or deprived of food. ( Emmanuel, B; Kennelly, JJ, 1984) |
| "Systemic ketosis was induced in first-parity gilts by the isocaloric substitution of glucose with 1,3-butylene glycol to supply 20% of the total dietary energy beginning on d 23 (23 BG) or d 60 (60 BG) of gestation." | 1.27 | Fetal hepatic and neural substrate utilization as affected by induced nutritional ketosis in swine. ( McMurtry, JP; Rosebrough, RW; Steele, NC, 1984) |
| "Post-exercise ketosis is not abolished by glucose ingestion immediately after exercise but is counteracted by simultaneous beta-adrenergic blockade." | 1.27 | beta-Adrenergic blockade counteracts starvational ketosis, but aggravates post-exercise ketosis in non-athletes. ( J de V Lochner, J; Koeslag, JH; Vahed, YA, 1988) |
| "Alcoholic ketosis occurs in alcoholics, who have been shown also to be more predisposed than normal to post-exercise ketosis (Chalmers, Sulaiman & Johnson, 1977)." | 1.27 | Ethanol ingestion and the development of post-exercise ketosis in non-alcoholic human subjects. ( Hadley, W; Koeslag, JH; Lochner, JD, 1988) |
| "3." | 1.27 | The effects of post-exercise glucose and alanine ingestion on plasma carnitine and ketosis in humans. ( Carlin, JI; Olson, EB; Peters, HA; Reddan, WG, 1987) |
| "Diabetic ketoacidosis is often associated with a temporary increase in protein excretion, but the mechanisms are not completely known." | 1.27 | Effect of 3-hydroxybutyrate infusion on urinary protein excretion in healthy man. ( Alberti, KG; Christensen, CK; Mogensen, CE; Pedersen, EB; Schmitz, O, 1986) |
| "Patients with respiratory acidosis had both intermediate probabilities of death and intermediate ratios when compared to inpatient controls (ICU patients without acidosis)." | 1.27 | Assessing redox status in human plasma: experience in critically ill patients. ( Davies, AO; Samuelson, WM, 1986) |
| "This study examined ketosis in response to 90 min of running before and after the ingestion of 50 g glucose or 50 g L-alanine in thirty-three athletes." | 1.27 | Post-exercise ketosis in post-prandial exercise: effect of glucose and alanine ingestion in humans. ( Koeslag, JH; Levinrad, LI; Lochner, JD; Sive, AA, 1985) |
| "Experimental ketosis was induced by feeding calves a diet containing 1,3 butanediol for 9 or 10 days." | 1.27 | Suppression of mitogenic response of bovine lymphocytes during experimental ketosis in calves. ( Hoy, DA; Klucinski, W; Littledike, ET; Targowski, SP, 1985) |
| "Maternal ketosis was induced in sows by feeding 20% of the dietary energy as 1,3-butylene glycol (BG), medium-chain triglycerides (MCT), or a combination of the two." | 1.26 | Effect of ketogenic diets in gestation on some characteristics of carbohydrate metabolism in fetal pig brain and liver. ( Frobish, LT; Rosebrough, RW; Steele, NC, 1981) |
| "Hyperketonemia was induced by 3 days of starvation or by infusion of 3-hydroxybutyrate in fed rats." | 1.26 | No effect of hyperketonemia on local cerebral glucose utilization in conscious rats. ( Corddry, DH; London, ED; Rapoport, SI, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 45 (58.44) | 18.7374 |
| 1990's | 5 (6.49) | 18.2507 |
| 2000's | 10 (12.99) | 29.6817 |
| 2010's | 11 (14.29) | 24.3611 |
| 2020's | 6 (7.79) | 2.80 |
| Authors | Studies |
|---|---|
| van Gastelen, S | 1 |
| Dijkstra, J | 1 |
| Alferink, SJJ | 1 |
| Binnendijk, G | 1 |
| Nichols, K | 1 |
| Zandstra, T | 1 |
| Bannink, A | 1 |
| Sholevar, C | 1 |
| Torjani, A | 1 |
| Kavanagh, TR | 1 |
| Yudkoff, C | 1 |
| Xiao, K | 1 |
| Swaminathan, V | 1 |
| Rshaidat, H | 1 |
| Bowne, WB | 1 |
| Krampitz, GW | 1 |
| Nevler, A | 1 |
| Yeo, CJ | 1 |
| Lavu, H | 1 |
| Puppel, K | 1 |
| Slósarz, J | 1 |
| Grodkowski, G | 1 |
| Solarczyk, P | 1 |
| Kostusiak, P | 1 |
| Kunowska-Slósarz, M | 1 |
| Grodkowska, K | 1 |
| Zalewska, A | 1 |
| Kuczyńska, B | 1 |
| Gołębiewski, M | 1 |
| Cao, S | 2 |
| Nishizawa, T | 1 |
| Matsumoto, T | 1 |
| Todaka, T | 1 |
| Sasano, M | 1 |
| Kent-Dennis, C | 1 |
| Penner, GB | 2 |
| Lambert, FN | 1 |
| Treberg, JR | 1 |
| Anderson, WG | 1 |
| Brandt, C | 1 |
| Evans, AN | 1 |
| Segebrecht, R | 1 |
| Moncure, M | 1 |
| Bennett, A | 1 |
| Geehan, D | 1 |
| Van Way, CW | 1 |
| Weide, L | 1 |
| Gross, JJ | 1 |
| Bruckmaier, RM | 1 |
| Chaidate, I | 1 |
| Somchai, C | 1 |
| Jos, N | 1 |
| Henk, H | 1 |
| Minuti, A | 1 |
| Ahmed, S | 1 |
| Trevisi, E | 1 |
| Piccioli-Cappelli, F | 1 |
| Bertoni, G | 1 |
| Jahan, N | 1 |
| Bani, P | 1 |
| Herdman, MT | 1 |
| Sriboonvorakul, N | 1 |
| Leopold, SJ | 1 |
| Douthwaite, S | 1 |
| Mohanty, S | 1 |
| Hassan, MM | 1 |
| Maude, RJ | 1 |
| Kingston, HW | 1 |
| Plewes, K | 1 |
| Charunwatthana, P | 1 |
| Silamut, K | 1 |
| Woodrow, CJ | 1 |
| Ghose, A | 1 |
| Chotinavich, K | 1 |
| Hossain, MA | 1 |
| Faiz, MA | 1 |
| Mishra, S | 1 |
| Leepipatpiboon, N | 1 |
| White, NJ | 1 |
| Day, NP | 1 |
| Tarning, J | 1 |
| Dondorp, AM | 1 |
| Smith, SW | 1 |
| Manini, AF | 1 |
| Szekely, T | 1 |
| Hoffman, RS | 1 |
| Aschenbach, JR | 1 |
| Gäbel, G | 1 |
| Rackwitz, R | 1 |
| Oba, M | 1 |
| Elliott, S | 1 |
| Smith, C | 1 |
| Cassidy, D | 1 |
| Prevost, M | 1 |
| Sun, Y | 1 |
| Servilla, KS | 1 |
| Massie, L | 1 |
| Glew, RH | 1 |
| Tzamaloukas, AH | 1 |
| Meier, H | 1 |
| Gschwend, S | 1 |
| Raimondi, S | 1 |
| Giambarba, C | 1 |
| Steele, MA | 1 |
| Dionissopoulos, L | 1 |
| AlZahal, O | 1 |
| Doelman, J | 1 |
| McBride, BW | 1 |
| Rehman, HU | 1 |
| Donovan, DC | 1 |
| Hippen, AR | 1 |
| Hurley, DJ | 1 |
| Chase, CC | 1 |
| Enemark, JM | 1 |
| Jørgensen, RJ | 1 |
| Kristensen, NB | 1 |
| Sasi, P | 1 |
| English, M | 1 |
| Berkley, J | 1 |
| Lowe, B | 1 |
| Shebe, M | 1 |
| Mwakesi, R | 1 |
| Kokwaro, G | 1 |
| Sabatini, S | 1 |
| Kurtzman, NA | 1 |
| Beattie, MA | 2 |
| Winder, WW | 2 |
| Pahl, MV | 1 |
| Vaziri, ND | 1 |
| Ness, R | 1 |
| Nathan, R | 1 |
| Maksy, M | 1 |
| Kauppinen, K | 1 |
| Haymond, MW | 2 |
| Pagliara, AS | 1 |
| Owen, OE | 1 |
| Caprio, S | 1 |
| Reichard, GA | 1 |
| Mozzoli, MA | 1 |
| Boden, G | 1 |
| Owen, RS | 1 |
| Oster, JR | 2 |
| Epstein, M | 1 |
| Targowski, SP | 2 |
| Klucinski, W | 2 |
| Rice, DA | 2 |
| McMurray, CH | 2 |
| Davidson, JF | 1 |
| Gröhn, Y | 2 |
| Lindberg, LA | 1 |
| Bruss, ML | 1 |
| Farver, TB | 1 |
| Dufva, GS | 1 |
| Bartley, EE | 1 |
| Dayton, AD | 1 |
| Riddell, DO | 1 |
| Blanchflower, WJ | 1 |
| Emmanuel, B | 1 |
| Kennelly, JJ | 1 |
| Steele, NC | 2 |
| Rosebrough, RW | 2 |
| McMurtry, JP | 1 |
| Frobish, LT | 1 |
| Stacpoole, PW | 1 |
| Harman, EM | 1 |
| Curry, SH | 1 |
| Baumgartner, TG | 1 |
| Misbin, RI | 1 |
| Bagnasco, SM | 1 |
| Gaydos, DS | 1 |
| Risquez, A | 1 |
| Preuss, HG | 1 |
| Corddry, DH | 1 |
| Rapoport, SI | 1 |
| London, ED | 1 |
| Herdt, TH | 1 |
| Stevens, JB | 1 |
| Olson, WG | 1 |
| Larson, V | 1 |
| Galanello, R | 1 |
| Cao, A | 1 |
| Olivieri, N | 1 |
| Hooper, RJ | 1 |
| Caspar, CB | 1 |
| Risti, B | 1 |
| Iten, PX | 1 |
| Jost, R | 1 |
| Russi, EW | 1 |
| Speich, R | 1 |
| Walsh, NP | 1 |
| Blannin, AK | 1 |
| Clark, AM | 1 |
| Cook, L | 1 |
| Robson, PJ | 1 |
| Gleeson, M | 1 |
| Pitt, JJ | 1 |
| Hauser, S | 1 |
| Tamaki, T | 1 |
| Shibata, Y | 1 |
| Node, Y | 1 |
| Yamamoto, Y | 1 |
| Teramoto, A | 1 |
| Piliero, PJ | 1 |
| Fish, DG | 1 |
| Nappert, G | 1 |
| Dunphy, E | 1 |
| Ruben, D | 1 |
| Mann, FA | 1 |
| Van Cappellen Van Walsum, AM | 1 |
| Jongsma, HW | 1 |
| Wevers, RA | 1 |
| Nijhuis, JG | 1 |
| Crevels, J | 1 |
| Engelke, UF | 1 |
| De Abreu, RA | 1 |
| Moolenaar, SH | 1 |
| Oeseburg, B | 1 |
| Nijland, R | 1 |
| Rodriguez, NR | 1 |
| Miles, JM | 1 |
| Schwenk, WF | 1 |
| Adams, JH | 1 |
| Koeslag, JH | 5 |
| Drackley, JK | 1 |
| Zhang, Y | 1 |
| Amaral, DM | 1 |
| Young, JW | 1 |
| Kawai, K | 1 |
| Ohmori, H | 1 |
| Okuda, Y | 1 |
| Yamashita, K | 1 |
| Vahed, YA | 2 |
| Lochner, JV | 1 |
| Paton, JB | 1 |
| Levitsky, LL | 1 |
| Fisher, DE | 1 |
| Nuwayhid, NF | 1 |
| Johnson, GF | 1 |
| Feld, RD | 1 |
| Alpert, HC | 1 |
| Rodriguez, GR | 1 |
| Vaamonde, CA | 1 |
| Leiter, LA | 1 |
| Josse, RG | 1 |
| West, ML | 1 |
| Halperin, ML | 1 |
| J de V Lochner, J | 1 |
| Davies, AO | 3 |
| Boado, R | 1 |
| Colombo, O | 1 |
| Zaninovich, AA | 1 |
| Hadley, W | 1 |
| Lochner, JD | 2 |
| Sorisky, A | 1 |
| Devlin, JT | 1 |
| Carlin, JI | 1 |
| Olson, EB | 1 |
| Peters, HA | 1 |
| Reddan, WG | 1 |
| Zusman, I | 1 |
| Ornoy, A | 1 |
| Cersosimo, E | 1 |
| Williams, P | 1 |
| Hoxworth, B | 1 |
| Lacy, W | 1 |
| Abumrad, N | 1 |
| Christensen, CK | 1 |
| Schmitz, O | 1 |
| Pedersen, EB | 1 |
| Alberti, KG | 1 |
| Mogensen, CE | 1 |
| Samuelson, WM | 2 |
| Adrogué, HJ | 1 |
| Chap, Z | 1 |
| Ishida, T | 1 |
| Field, JB | 1 |
| Levinrad, LI | 1 |
| Sive, AA | 1 |
| Féry, F | 1 |
| Balasse, EO | 1 |
| Littledike, ET | 1 |
| Hoy, DA | 1 |
| Goldstein, L | 1 |
| Perlman, DF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacotoxicology of Trichloroethylene Metabolites: Short-term Effect of DCA on in Vivo Tyrosine Catabolism and MAAI Expression[NCT00865514] | 2 participants (Actual) | Interventional | 2011-08-31 | Terminated (stopped due to Difficulty in obtaining the solution from the compounding pharmacies caused a two year delay in start-up; the funding ended prior to study completion.) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for 3-hydroxybutyric acid and Acidosis
| Article | Year |
|---|---|
Review: Metabolic challenges in lactating dairy cows and their assessment via established and novel indicators in milk.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Biomarkers; Cattle; Cattle Diseases; Diet; Fatty Acids; Fe | 2019 |
Ketotic hypoglycaemia.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Adolescent; Adrenocorticotropic Hormone; Adult; Alan | 1983 |
Ketosis of starvation: a revisit and new perspectives.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Gluconeogenesis; Humans; Hydrogen; Hydroxyb | 1983 |
Acid-base aspects of ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Acid-Base Equilibrium; Acidosis; Acidosis, Respiratory; Alcoholism; Alkalosis | 1984 |
[Alcoholic ketoacidosis].
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Alcoholism; Diagnosis, Differential; Ethanol; Female | 1993 |
1 trial available for 3-hydroxybutyric acid and Acidosis
| Article | Year |
|---|---|
Experimental acute rumen acidosis in sheep: consequences on clinical, rumen, and gastrointestinal permeability conditions and blood chemistry.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Blood Glucose; Ceruloplasmin; Cross-Over Studies; Gastroin | 2014 |
71 other studies available for 3-hydroxybutyric acid and Acidosis
| Article | Year |
|---|---|
Abomasal infusion of corn starch and β-hydroxybutyrate in early-lactation Holstein-Friesian dairy cows to induce hindgut and metabolic acidosis.
Topics: 3-Hydroxybutyric Acid; Abomasum; Acidosis; Animals; Cattle; Cattle Diseases; Diet; Digestion; Lactat | 2021 |
Euglycemic diabetic ketoacidosis (EDKA) after pancreaticoduodenectomy: An under-recognized metabolic abnormality with outcome implications.
Topics: 3-Hydroxybutyric Acid; Acidosis; Diabetes Mellitus; Diabetic Ketoacidosis; Humans; Insulin; Male; Pa | 2023 |
Comparison of Enzyme Activity in Order to Describe the Metabolic Profile of Dairy Cows during Early Lactation.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Aspartate Aminotransferases; Cattle; Cattle Diseases; Fema | 2022 |
Diabetic Ketoalkalosis: A Common Yet Easily Overlooked Alkalemic Variant of Diabetic Ketoacidosis Associated with Mixed Acid-Base Disorders.
Topics: 3-Hydroxybutyric Acid; Acid-Base Imbalance; Acidosis; Adult; Alkalosis; Bicarbonates; Diabetes Melli | 2023 |
Alcoholic ketoacidosis evaluated with a point-of-care capillary beta-hydroxybutyrate measurement device.
Topics: 3-Hydroxybutyric Acid; Acidosis; Electrolytes; Humans; Ketosis; Point-of-Care Systems; Retrospective | 2023 |
Effects of lipopolysaccharide exposure on the inflammatory response, butyrate flux, and metabolic function of the ruminal epithelium using an ex vivo model.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Butyrates; Cattle; Cattle Diseases; Diet; Epithelium; Gene | 2021 |
The physiological stress response of the Atlantic stingray (Hypanus sabinus) to aerial exposure.
Topics: 3-Hydroxybutyric Acid; Acidosis; Air; Animals; Blood Glucose; Homeostasis; Ketone Bodies; Lactic Aci | 2018 |
Ketoacidosis in Euglycemic Patients With Type 2 Diabetes After Abdominal Surgery.
Topics: 3-Hydroxybutyric Acid; Abdomen; Acidosis; Aged; Anions; Bicarbonates; Blood Glucose; Diabetes Mellit | 2019 |
A cow-level association of ruminal pH on body condition score, serum beta-hydroxybutyrate and postpartum disorders in Thai dairy cattle.
Topics: 3-Hydroxybutyric Acid; Acidosis; Anestrus; Animals; Asian People; Blood Urea Nitrogen; Body Composit | 2014 |
The role of previously unmeasured organic acids in the pathogenesis of severe malaria.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adolescent; Adult; Aged; Chromatography, Liquid; Female; Humans; Hy | 2015 |
Bedside detection of urine beta-hydroxybutyrate in diagnosing metabolic acidosis.
Topics: 3-Hydroxybutyric Acid; Acidosis; Diabetic Ketoacidosis; Emergency Service, Hospital; Humans; Hydroge | 2008 |
Epithelial capacity for apical uptake of short chain fatty acids is a key determinant for intraruminal pH and the susceptibility to subacute ruminal acidosis in sheep.
Topics: 3-Hydroxybutyric Acid; Acetates; Acidosis; Animals; Bicarbonates; Biological Transport; Butyrates; E | 2009 |
The post-mortem relationship between beta-hydroxybutyrate (BHB), acetone and ethanol in ketoacidosis.
Topics: 3-Hydroxybutyric Acid; Acetone; Acidosis; Alcohol Drinking; Biomarkers; Central Nervous System Depre | 2010 |
Repeated intoxication presenting with azotemia, elevated serum osmolal gap, and metabolic acidosis with high anion gap: differential diagnosis, management, and prognosis.
Topics: 2-Propanol; 3-Hydroxybutyric Acid; Acetoacetates; Acetone; Acid-Base Equilibrium; Acidosis; Aged; Al | 2012 |
[Ethanol, sugar, acid and coma].
Topics: 3-Hydroxybutyric Acid; Acid-Base Equilibrium; Acidosis; Alcohol-Related Disorders; Blood Glucose; Di | 2011 |
Rumen epithelial adaptation to ruminal acidosis in lactating cattle involves the coordinated expression of insulin-like growth factor-binding proteins and a cholesterolgenic enzyme.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adaptation, Physiological; Animals; Cattle; Cholesterol; Diet; Epit | 2012 |
A woman with ketoacidosis but not diabetes.
Topics: 2-Propanol; 3-Hydroxybutyric Acid; Abdominal Pain; Acidosis; Adult; Alcoholism; Diabetic Ketoacidosi | 2012 |
The role of acidogenic diets and beta-hydroxybutyate on lymphocyte proliferation and serum antibody response against bovine respiratory viruses in Holstein steers.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Antibodies, Viral; Blood Chemical Analysis; Cattle; Diet; | 2003 |
An evaluation of parameters for the detection of subclinical rumen acidosis in dairy herds.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animal Feed; Animals; Cattle; Cattle Diseases; Fatty Acids, Volatil | 2004 |
Characterisation of metabolic acidosis in Kenyan children admitted to hospital for acute non-surgical conditions.
Topics: 3-Hydroxybutyric Acid; Acidosis; Acute Disease; Biomarkers; Child, Preschool; Creatinine; Female; Ga | 2006 |
Bicarbonate therapy in severe metabolic acidosis.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Bicarbonates; Cell Death; Diabetic Ketoacidosis; Hum | 2009 |
Mechanism of training-induced attenuation of postexercise ketosis.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Carnitine; Cyclic AMP; Hydroxybutyrates; Ketosis; Liver; L | 1984 |
Association of beta hydroxybutyric acidosis with isoniazid intoxication.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adult; Bicarbonates; Diazepam; Female; Humans; Hydroxybutyrates; Is | 1984 |
ALAT, AP, ASAT, GGT, OCT activities and urea and total bilirubin concentrations in plasma of normal and ketotic dairy cows.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Alanine Transaminase; Alkaline Phosphatase; Animals; | 1984 |
Reduction in mitogenic response of bovine lymphocytes by ketone bodies.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Butyrates; Butyric Acid; Cattle; Cattle Diseases; Dairying | 1983 |
Ketosis in dairy cows caused by low levels of lincomycin in concentrate feed.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animal Feed; Animals; Cattle; Cattle Diseases; Disease Outbreaks; F | 1983 |
Fatty infiltration of liver in spontaneously ketotic dairy cows.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Biopsy, Needle; Blood Glucose; Cattle; Catt | 1983 |
Effect of niacin supplementation on milk production and ketosis of dairy cattle.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Blood Glucose; Cattle; Cattle Diseases; Fatty Acids, Nones | 1983 |
Automated kinetic method for D-3-hydroxybutyrate in plasma or serum.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Autoanalysis; Cattle; Humans; Hydrogen-Ion Concentration; | 1984 |
Effect of propionic acid on ketogenesis in lactating sheep fed restricted rations or deprived of food.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Blood Glucose; Diet; Fatty Acids, Nonesteri | 1984 |
Fetal hepatic and neural substrate utilization as affected by induced nutritional ketosis in swine.
Topics: 3-Hydroxybutyric Acid; Acetates; Acidosis; Animal Feed; Animals; Brain; Butylene Glycols; Fatty Acid | 1984 |
Effect of ketogenic diets in gestation on some characteristics of carbohydrate metabolism in fetal pig brain and liver.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Body Composition; Brain; Butylene Glycols; Dietary Carbohy | 1981 |
Treatment of lactic acidosis with dichloroacetate.
Topics: 3-Hydroxybutyric Acid; Acetates; Acidosis; Adolescent; Adult; Aged; Alanine; Bicarbonates; Blood Pre | 1983 |
The regulation of renal ammoniagenesis in the rat by extracellular factors. III. Effects of various fuels on in vitro ammoniagenesis.
Topics: 3-Hydroxybutyric Acid; Acidosis; Ammonia; Animals; Carboxylic Acids; Energy Metabolism; Female; Glut | 1983 |
No effect of hyperketonemia on local cerebral glucose utilization in conscious rats.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Brain; Deoxy Sugars; Deoxyglucose; Glucose; | 1982 |
Blood concentrations of beta hydroxybutyrate in clinically normal Holstein-Friesian herds and in those with a high prevalence of clinical ketosis.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Blood Glucose; Cattle; Cattle Diseases; Female; Hydroxybut | 1981 |
Induction of fetal hemoglobin in the presence of increased 3-hydroxybutyric acid associated with beta-ketothiolase deficiency.
Topics: 3-Hydroxybutyric Acid; Acetyl-CoA C-Acyltransferase; Acidosis; Child, Preschool; Fetal Hemoglobin; H | 1994 |
Alcoholic ketoacidosis: the late presentation of acidosis in an alcoholic.
Topics: 3-Hydroxybutyric Acid; Acidosis; Alcoholism; Analgesics; Antiemetics; Blood Chemical Analysis; Fluid | 1994 |
The effects of high-intensity intermittent exercise on the plasma concentrations of glutamine and organic acids.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adult; Ammonia; Exercise; Exercise Test; Fatty Acids, Nonesterified | 1998 |
Transient 5-oxoprolinuria and high anion gap metabolic acidosis: clinical and biochemical findings in eleven subjects.
Topics: 3-Hydroxybutyric Acid; Acetaminophen; Acidosis; Adolescent; Adult; Aged; Aged, 80 and over; Analgesi | 1998 |
[Metabolic acidosis and ketone body in severely head-injured patients].
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Adult; Aged; Biomarkers; Catecholamines; Craniocereb | 2000 |
Isoniazid-induced beta-hydroxybutyric acidosis.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adult; AIDS-Related Opportunistic Infections; Drug Interactions; Fe | 2001 |
Determination of serum organic acids in puppies with naturally acquired parvoviral enteritis.
Topics: 3-Hydroxybutyric Acid; Acetates; Acid-Base Equilibrium; Acidosis; Animals; Animals, Newborn; Blood G | 2002 |
1H-NMR spectroscopy of cerebrospinal fluid of fetal sheep during hypoxia-induced acidemia and recovery.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Choline; Citric Acid; Creatinine; Energy Metabolism; Femal | 2002 |
Effects of acute metabolic acidosis and alkalosis on leucine metabolism in conscious dogs.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Alkalosis; Amino Acids; Animals; Bicarbonates; Blood | 1989 |
Post-exercise ketosis and the glycogen content of liver and muscle in rats on a high carbohydrate diet.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Body Weight; Dietary Carbohydrates; Glycogen; Hydroxybutyr | 1989 |
Metabolic effects of intraruminal administration of 1,3-butanediol or tributyrin in lactating goats.
Topics: 3-Hydroxybutyric Acid; Acidosis; Analysis of Variance; Animals; Blood Glucose; Butylene Glycols; Fem | 1989 |
Effects of 3-hydroxybutyrate and hyperosmolarity on glucagon release from isolated perfused canine pancreas.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Arginine; Dogs; Glucagon; Glucose; Hydroxybutyrates; In Vi | 1989 |
D2-dopaminergic blockade does not influence post-exercise ketosis in non-athletes.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adolescent; Adult; Blood Glucose; Dietary Carbohydrates; Fatty Acid | 1989 |
Placental transfer and fetal effects of maternal sodium beta-hydroxybutyrate infusion in the baboon.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Energy Metabolism; Female; Fetus; Hydroxybutyrates; Ketone | 1989 |
Multipoint kinetic method for simultaneously measuring the combined concentrations of acetoacetate-beta-hydroxybutyrate and lactate-pyruvate.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acid-Base Equilibrium; Acidosis; Centrifugation; Humans; Hydro | 1989 |
Effect of acute reversal of experimentally-induced ketoacidosis with sodium bicarbonate on the plasma concentrations of phosphorus and potassium.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animals; Bicarbonates; Female; Hydroxybutyrates; Phosphorus; Potass | 1988 |
Severe metabolic acidosis induced in a patient during fasting by KCl administration.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adolescent; Ammonia; Bicarbonates; Fasting; Female; Humans; Hydroxy | 1988 |
beta-Adrenergic blockade counteracts starvational ketosis, but aggravates post-exercise ketosis in non-athletes.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adolescent; Adrenergic beta-Antagonists; Adult; Blood Glucose; Fema | 1988 |
Attenuation of postexercise ketosis in fasted endurance-trained rats.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adaptation, Physiological; Animals; Carnitine; Cyclic AMP; Fasting; | 1985 |
Effects of endogenous redox-active compounds on coupling of human beta 2-adrenergic receptors.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Adolescent; Adult; Glutathione; Glutathione Disulfid | 1986 |
Effects of diabetes, beta-hydroxybutyric acid and metabolic acidosis on the pituitary-thyroid axis in the rat.
Topics: 3-Hydroxybutyric Acid; Acidosis; Ammonium Chloride; Animals; Diabetes Mellitus, Experimental; Hydrox | 1985 |
Ethanol ingestion and the development of post-exercise ketosis in non-alcoholic human subjects.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adult; Alcohol Drinking; Blood Glucose; Ethanol; Fatty Acids, Nones | 1988 |
Intraoperative ketoacidosis and malnutrition.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Acute Disease; Drug Therapy, Combination; Female; Gl | 1988 |
The effects of post-exercise glucose and alanine ingestion on plasma carnitine and ketosis in humans.
Topics: 3-Hydroxybutyric Acid; Acidosis; Adult; Alanine; Carnitine; Fasting; Fatty Acids, Nonesterified; Glu | 1987 |
Effects of hyperglycemia and ketone bodies on the in vitro development of early somite rate embryos.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Blood Glucose; Congenital Abnormalities; Cu | 1987 |
Glutamine blocks lipolysis and ketogenesis of fasting.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Consciousness; Dogs; Fasting; Fatty Acids, | 1986 |
Effect of 3-hydroxybutyrate infusion on urinary protein excretion in healthy man.
Topics: 3-Hydroxybutyric Acid; Acid-Base Equilibrium; Acidosis; Adult; Albuminuria; beta 2-Microglobulin; He | 1986 |
Nonequilibrium of two redox couplets in human plasma: lactate-pyruvate and beta-hydroxybutyrate-acetoacetate.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Adult; Female; Humans; Hydroxybutyrates; Lactates; M | 1986 |
Assessing redox status in human plasma: experience in critically ill patients.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Acidosis, Respiratory; Adult; Aged; Critical Care; F | 1986 |
Role of the endocrine pancreas in the kalemic response to acute metabolic acidosis in conscious dogs.
Topics: 3-Hydroxybutyric Acid; Acidosis; Acute Disease; Animals; Bicarbonates; Blood Glucose; Dogs; Electrol | 1985 |
Post-exercise ketosis in post-prandial exercise: effect of glucose and alanine ingestion in humans.
Topics: 3-Hydroxybutyric Acid; Acidosis; Alanine; Blood Glucose; Fatty Acids, Nonesterified; Glucagon; Gluco | 1985 |
Ketone body production and disposal in diabetic ketosis. A comparison with fasting ketosis.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Adolescent; Adult; Diabetes Mellitus, Type 1; Diabet | 1985 |
Suppression of mitogenic response of bovine lymphocytes during experimental ketosis in calves.
Topics: 3-Hydroxybutyric Acid; Acidosis; Animal Feed; Animals; Butylene Glycols; Cattle; Cattle Diseases; Di | 1985 |
Propionate loading test for liver function in spontaneously ketotic dairy cows.
Topics: 3-Hydroxybutyric Acid; Acetoacetates; Acidosis; Animals; Blood Glucose; Cattle; Cattle Diseases; Fem | 1985 |
Renal oxidative metabolism and ammoniagenesis.
Topics: 3-Hydroxybutyric Acid; Acidosis; Ammonia; Animals; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazon | 1985 |