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3-hydroxybenzylhydrazine and Pheochromocytoma

3-hydroxybenzylhydrazine has been researched along with Pheochromocytoma in 2 studies

3-hydroxybenzylhydrazine: decarboxylase inhibitor; RN given refers to parent cpd; structure

Pheochromocytoma: A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)

Research Excerpts

ExcerptRelevanceReference
"In PC12 rat pheochromocytoma cells differentiated with nerve growth factor (NGF), neuropeptide Y inhibited depolarization-stimulated catecholamine synthesis as determined by in situ measurement of 3,4-dihydroxyphenylalanine (DOPA) production in the presence of the decarboxylase inhibitor m-hydroxybenzylhydrazine (NSD-1015)."7.69Neuropeptide Y inhibits depolarization-stimulated catecholamine synthesis in rat pheochromocytoma cells. ( McCullough, LA; Westfall, TC, 1995)
"In PC12 rat pheochromocytoma cells differentiated with nerve growth factor (NGF), neuropeptide Y inhibited depolarization-stimulated catecholamine synthesis as determined by in situ measurement of 3,4-dihydroxyphenylalanine (DOPA) production in the presence of the decarboxylase inhibitor m-hydroxybenzylhydrazine (NSD-1015)."3.69Neuropeptide Y inhibits depolarization-stimulated catecholamine synthesis in rat pheochromocytoma cells. ( McCullough, LA; Westfall, TC, 1995)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Newcomer, TA1
Rosenberg, PA1
Aizenman, E1
McCullough, LA1
Westfall, TC1

Other Studies

2 other studies available for 3-hydroxybenzylhydrazine and Pheochromocytoma

ArticleYear
TOPA quinone, a kainate-like agonist and excitotoxin is generated by a catecholaminergic cell line.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1995, Volume: 15, Issue:4

    Topics: Adrenal Gland Neoplasms; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Catecholamines; Chro

1995
Neuropeptide Y inhibits depolarization-stimulated catecholamine synthesis in rat pheochromocytoma cells.
    European journal of pharmacology, 1995, Dec-20, Volume: 287, Issue:3

    Topics: Adrenal Gland Neoplasms; Analysis of Variance; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aro

1995