Page last updated: 2024-11-05

3-hydroxyaspartic acid and Schizophrenia

3-hydroxyaspartic acid has been researched along with Schizophrenia in 1 studies

3-hydroxyaspartic acid: RN given refers to cpd without isomeric designation
3-hydroxyaspartic acid : A hydroxy-amino acid that is aspartic acid in which one of the methylene hydrogens has been replaced by a hydroxy group.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"The upregulation of the initiating step of the kynurenine pathway was demonstrated in postmortem anterior cingulated cortex from individuals with schizophrenia and bipolar disorder."3.74Tryptophan breakdown pathway in bipolar mania. ( Kim, YK; Leonard, BE; Myint, AM; Park, SH; Scharpé, S; Steinbusch, HW; Verkerk, R, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Myint, AM1
Kim, YK1
Verkerk, R1
Park, SH1
Scharpé, S1
Steinbusch, HW1
Leonard, BE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Vortioxetine Monotherapy for Major Depressive Disorder in Type 2 Diabetes: Role of Inflammation, Kynurenine Pathway, and Structural and Functional Brain Connectivity as Biomarkers[NCT03580967]Phase 40 participants (Actual)Interventional2019-07-01Withdrawn (stopped due to COVID-19 Pandemic interfered with Pt recruitment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

1 other study available for 3-hydroxyaspartic acid and Schizophrenia

ArticleYear
Tryptophan breakdown pathway in bipolar mania.
    Journal of affective disorders, 2007, Volume: 102, Issue:1-3

    Topics: Adult; Aspartic Acid; Bipolar Disorder; Brief Psychiatric Rating Scale; Female; Gyrus Cinguli; Human

2007