3-hydroxyaspartic acid has been researched along with Nerve Degeneration in 6 studies
3-hydroxyaspartic acid: RN given refers to cpd without isomeric designation
3-hydroxyaspartic acid : A hydroxy-amino acid that is aspartic acid in which one of the methylene hydrogens has been replaced by a hydroxy group.
Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.
| Excerpt | Relevance | Reference |
|---|---|---|
| "24 h after injection, rigidity and catalepsy were measured, as well as, at the end of the three week period, locomotion, rearing and exploratory behavior." | 1.31 | Local application of L- threo-hydroxyaspartate and malonate in rats in vivo induces rigidity and damages neurons of the substantia nigra, pars compacta. ( Loopuijt, LD, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, J | 1 |
| Guo, Y | 1 |
| Sun, M | 1 |
| Li, B | 1 |
| Zhang, Y | 1 |
| Li, C | 1 |
| Nagańska, E | 1 |
| Taraszewska, A | 1 |
| Matyja, E | 1 |
| Grieb, P | 1 |
| Rafałowska, J | 1 |
| Loopuijt, LD | 1 |
| Zheng, S | 1 |
| Zuo, Z | 1 |
| Velasco, I | 1 |
| Tapia, R | 1 |
| Massieu, L | 1 |
| Bar-Peled, O | 1 |
| Knudson, M | 1 |
| Korsmeyer, SJ | 1 |
| Rothstein, JD | 1 |
6 other studies available for 3-hydroxyaspartic acid and Nerve Degeneration
| Article | Year |
|---|---|
Iron is a potential key mediator of glutamate excitotoxicity in spinal cord motor neurons.
Topics: Analysis of Variance; Animals; Aspartic Acid; Cation Transport Proteins; Deferoxamine; Ferritins; Gl | 2009 |
Neuroprotective effect of erythropoietin in amyotrophic lateral sclerosis (ALS) model in vitro. Ultrastructural study.
Topics: Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Cell Membrane; Cytoplasm; Endoplasmic Reticul | 2010 |
Local application of L- threo-hydroxyaspartate and malonate in rats in vivo induces rigidity and damages neurons of the substantia nigra, pars compacta.
Topics: Animals; Aspartic Acid; Behavior, Animal; Brain Mapping; Catalepsy; Cell Count; Coloring Agents; Loc | 2002 |
Isoflurane preconditioning reduces purkinje cell death in an in vitro model of rat cerebellar ischemia.
Topics: Amino Acid Transport System X-AG; Anesthetics, Inhalation; Animals; Aspartic Acid; Brain Ischemia; C | 2003 |
Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures.
Topics: Animals; Anti-Bacterial Agents; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Dicarboxylic Acids; | 1996 |
Motor neuron degeneration is attenuated in bax-deficient neurons in vitro.
Topics: Animals; Aspartic Acid; Astrocytes; bcl-2-Associated X Protein; Cell Death; Cell Division; Cell Nucl | 1999 |