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3-hydroxyaspartic acid and Nerve Degeneration

3-hydroxyaspartic acid has been researched along with Nerve Degeneration in 6 studies

3-hydroxyaspartic acid: RN given refers to cpd without isomeric designation
3-hydroxyaspartic acid : A hydroxy-amino acid that is aspartic acid in which one of the methylene hydrogens has been replaced by a hydroxy group.

Nerve Degeneration: Loss of functional activity and trophic degeneration of nerve axons and their terminal arborizations following the destruction of their cells of origin or interruption of their continuity with these cells. The pathology is characteristic of neurodegenerative diseases. Often the process of nerve degeneration is studied in research on neuroanatomical localization and correlation of the neurophysiology of neural pathways.

Research Excerpts

ExcerptRelevanceReference
"24 h after injection, rigidity and catalepsy were measured, as well as, at the end of the three week period, locomotion, rearing and exploratory behavior."1.31Local application of L- threo-hydroxyaspartate and malonate in rats in vivo induces rigidity and damages neurons of the substantia nigra, pars compacta. ( Loopuijt, LD, 2002)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yu, J1
Guo, Y1
Sun, M1
Li, B1
Zhang, Y1
Li, C1
Nagańska, E1
Taraszewska, A1
Matyja, E1
Grieb, P1
Rafałowska, J1
Loopuijt, LD1
Zheng, S1
Zuo, Z1
Velasco, I1
Tapia, R1
Massieu, L1
Bar-Peled, O1
Knudson, M1
Korsmeyer, SJ1
Rothstein, JD1

Other Studies

6 other studies available for 3-hydroxyaspartic acid and Nerve Degeneration

ArticleYear
Iron is a potential key mediator of glutamate excitotoxicity in spinal cord motor neurons.
    Brain research, 2009, Feb-27, Volume: 1257

    Topics: Analysis of Variance; Animals; Aspartic Acid; Cation Transport Proteins; Deferoxamine; Ferritins; Gl

2009
Neuroprotective effect of erythropoietin in amyotrophic lateral sclerosis (ALS) model in vitro. Ultrastructural study.
    Folia neuropathologica, 2010, Volume: 48, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Cell Membrane; Cytoplasm; Endoplasmic Reticul

2010
Local application of L- threo-hydroxyaspartate and malonate in rats in vivo induces rigidity and damages neurons of the substantia nigra, pars compacta.
    Journal of neural transmission (Vienna, Austria : 1996), 2002, Volume: 109, Issue:10

    Topics: Animals; Aspartic Acid; Behavior, Animal; Brain Mapping; Catalepsy; Cell Count; Coloring Agents; Loc

2002
Isoflurane preconditioning reduces purkinje cell death in an in vitro model of rat cerebellar ischemia.
    Neuroscience, 2003, Volume: 118, Issue:1

    Topics: Amino Acid Transport System X-AG; Anesthetics, Inhalation; Animals; Aspartic Acid; Brain Ischemia; C

2003
Inhibition of glutamate uptake induces progressive accumulation of extracellular glutamate and neuronal damage in rat cortical cultures.
    Journal of neuroscience research, 1996, Jun-15, Volume: 44, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Aspartic Acid; Cells, Cultured; Cerebral Cortex; Dicarboxylic Acids;

1996
Motor neuron degeneration is attenuated in bax-deficient neurons in vitro.
    Journal of neuroscience research, 1999, Mar-01, Volume: 55, Issue:5

    Topics: Animals; Aspartic Acid; Astrocytes; bcl-2-Associated X Protein; Cell Death; Cell Division; Cell Nucl

1999