3-hydroxyaspartic acid has been researched along with Amyotrophic Lateral Sclerosis in 3 studies
3-hydroxyaspartic acid: RN given refers to cpd without isomeric designation
3-hydroxyaspartic acid : A hydroxy-amino acid that is aspartic acid in which one of the methylene hydrogens has been replaced by a hydroxy group.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kosuge, Y | 1 |
| Sekikawa-Nishida, K | 1 |
| Negi, H | 1 |
| Ishige, K | 1 |
| Ito, Y | 1 |
| Nagańska, E | 1 |
| Taraszewska, A | 1 |
| Matyja, E | 1 |
| Grieb, P | 1 |
| Rafałowska, J | 1 |
| Rothstein, JD | 1 |
| Jin, L | 1 |
| Dykes-Hoberg, M | 1 |
| Kuncl, RW | 1 |
3 other studies available for 3-hydroxyaspartic acid and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Characterization of chronic glutamate-mediated motor neuron toxicity in organotypic spinal cord culture prepared from ALS model mice.
Topics: Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Caspase 12; Cell Death; Cell Survival; Diseas | 2009 |
Neuroprotective effect of erythropoietin in amyotrophic lateral sclerosis (ALS) model in vitro. Ultrastructural study.
Topics: Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Cell Membrane; Cytoplasm; Endoplasmic Reticul | 2010 |
Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity.
Topics: Amyotrophic Lateral Sclerosis; Animals; Aspartic Acid; Biological Transport, Active; Choline O-Acety | 1993 |