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3-hydroxyanthranilic acid and Injuries, Spinal Cord

3-hydroxyanthranilic acid has been researched along with Injuries, Spinal Cord in 4 studies

3-Hydroxyanthranilic Acid: An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
3-hydroxyanthranilic acid : An aminobenzoic acid that is benzoic acid substituted at C-2 by an amine group and at C-3 by a hydroxy group. It is an intermediate in the metabolism of the amino acid tryptophan.
3-hydroxyanthranilate : A hydroxybenzoate that is the conjugate base of 3-hydroxyanthranilic acid.

Research Excerpts

ExcerptRelevanceReference
"Standardized spinal cord injuries were produced in anesthetized guinea pigs, using lateral compression of the spinal cord."1.40Effects of methylprednisolone and 4-chloro-3-hydroxyanthranilic acid in experimental spinal cord injury in the guinea pig appear to be mediated by different and potentially complementary mechanisms. ( Blight, AR; Gay, EA; Heyes, MP; Yates, JR, 2014)
"Quinolinic acid (QUIN) is an excitotoxic tryptophan metabolite that is produced by activated macrophages."1.29Quinolinic acid accumulation and functional deficits following experimental spinal cord injury. ( Blight, AR; Cohen, TI; Heyes, MP; Saito, K, 1995)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's1 (25.00)29.6817
2010's1 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yates, JR2
Gay, EA1
Heyes, MP4
Blight, AR3
Cohen, TI1
Saito, K1

Reviews

1 review available for 3-hydroxyanthranilic acid and Injuries, Spinal Cord

ArticleYear
The kynurenine pathway and neurologic disease. Therapeutic strategies.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: 3-Hydroxyanthranilic Acid; Animals; Gerbillinae; Guinea Pigs; Humans; Kynurenine; Macrophage Activat

1996

Other Studies

3 other studies available for 3-hydroxyanthranilic acid and Injuries, Spinal Cord

ArticleYear
Effects of methylprednisolone and 4-chloro-3-hydroxyanthranilic acid in experimental spinal cord injury in the guinea pig appear to be mediated by different and potentially complementary mechanisms.
    Spinal cord, 2014, Volume: 52, Issue:9

    Topics: 3-Hydroxyanthranilic Acid; Animals; Behavior, Animal; Disease Models, Animal; Evoked Potentials, Som

2014
4-chloro-3-hydroxyanthranilate reduces local quinolinic acid synthesis, improves functional recovery, and preserves white matter after spinal cord injury.
    Journal of neurotrauma, 2006, Volume: 23, Issue:6

    Topics: 3-Hydroxyanthranilic Acid; Algorithms; Animals; Behavior, Animal; Blood-Brain Barrier; Female; Guine

2006
Quinolinic acid accumulation and functional deficits following experimental spinal cord injury.
    Brain : a journal of neurology, 1995, Volume: 118 ( Pt 3)

    Topics: 3-Hydroxyanthranilate 3,4-Dioxygenase; 3-Hydroxyanthranilic Acid; Animals; Dioxygenases; Evoked Pote

1995