3-hydroxyanthranilic acid has been researched along with Cataract in 5 studies
3-Hydroxyanthranilic Acid: An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
3-hydroxyanthranilic acid : An aminobenzoic acid that is benzoic acid substituted at C-2 by an amine group and at C-3 by a hydroxy group. It is an intermediate in the metabolism of the amino acid tryptophan.
3-hydroxyanthranilate : A hydroxybenzoate that is the conjugate base of 3-hydroxyanthranilic acid.
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The kynurenine pathway catabolite 3-hydroxykynurenine (3HK) and redox-active metals such as copper and iron are implicated in cataractogenesis." | 3.70 | 3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction. ( Atwood, CS; Bowden, EF; Bush, AI; Chylack, LT; Faget, KY; Goldstein, LE; Hartshorn, M; Huang, X; Leopold, MC; Lim, JT; Muffat, JA; Saunders, AJ; Scarpa, RC; Tanzi, RE, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Elderfield, AJ | 1 |
| Truscott, RJ | 4 |
| Goldstein, LE | 1 |
| Leopold, MC | 1 |
| Huang, X | 1 |
| Atwood, CS | 1 |
| Saunders, AJ | 1 |
| Hartshorn, M | 1 |
| Lim, JT | 1 |
| Faget, KY | 1 |
| Muffat, JA | 1 |
| Scarpa, RC | 1 |
| Chylack, LT | 1 |
| Bowden, EF | 1 |
| Tanzi, RE | 1 |
| Bush, AI | 1 |
| Pyne, SG | 1 |
| Manthey, M | 1 |
| Martinez, MG | 1 |
| Martin, F | 1 |
1 review available for 3-hydroxyanthranilic acid and Cataract
| Article | Year |
|---|---|
Reactive metabolite hypothesis for human senile cataract.
Topics: 3-Hydroxyanthranilic Acid; Aging; Cataract; Crystallins; Humans; Lens, Crystalline; Models, Biologic | 1991 |
4 other studies available for 3-hydroxyanthranilic acid and Cataract
| Article | Year |
|---|---|
Is an altered tryptophan metabolism responsible for age-related cataract?
Topics: 3-Hydroxyanthranilic Acid; Aged; Cataract; Chromatography, High Pressure Liquid; Female; Humans; Kyn | 1996 |
3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction.
Topics: 3-Hydroxyanthranilic Acid; Animals; Ascorbic Acid; Cataract; Cattle; Copper; Crystallins; Electroche | 2000 |
Decolouration of the lens pigment in senile nuclear cataract.
Topics: 3-Hydroxyanthranilic Acid; Animals; Borohydrides; Cataract; Cattle; Crystallins; Dihydroxyphenylalan | 1990 |
The reaction of proteins with 3-hydroxyanthranilic acid as a possible model for senile nuclear cataract in man.
Topics: 3-Hydroxyanthranilic Acid; Animals; Cataract; Cattle; Chromatography, Gel; Color; Crystallins; Human | 1989 |