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3-hydroxyanthranilic acid and Brain Ischemia

3-hydroxyanthranilic acid has been researched along with Brain Ischemia in 1 studies

3-Hydroxyanthranilic Acid: An oxidation product of tryptophan metabolism. It may be a free radical scavenger and a carcinogen.
3-hydroxyanthranilic acid : An aminobenzoic acid that is benzoic acid substituted at C-2 by an amine group and at C-3 by a hydroxy group. It is an intermediate in the metabolism of the amino acid tryptophan.
3-hydroxyanthranilate : A hydroxybenzoate that is the conjugate base of 3-hydroxyanthranilic acid.

Brain Ischemia: Localized reduction of blood flow to brain tissue due to arterial obstruction or systemic hypoperfusion. This frequently occurs in conjunction with brain hypoxia (HYPOXIA, BRAIN). Prolonged ischemia is associated with BRAIN INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Post-stroke inflammation may induce upregulation of the kynurenine (KYN) pathway for tryptophan (TRP) oxidation, resulting in neuroprotective (kynurenic acid, KA) and neurotoxic metabolites (3-hydroxyanthranillic acid, 3-HAA)."7.76The role of tryptophan catabolism along the kynurenine pathway in acute ischemic stroke. ( Aerts, T; Brouns, R; De Deyn, PP; De Surgeloose, D; Scharpé, S; Verkerk, R; Wauters, A, 2010)
"Post-stroke inflammation may induce upregulation of the kynurenine (KYN) pathway for tryptophan (TRP) oxidation, resulting in neuroprotective (kynurenic acid, KA) and neurotoxic metabolites (3-hydroxyanthranillic acid, 3-HAA)."3.76The role of tryptophan catabolism along the kynurenine pathway in acute ischemic stroke. ( Aerts, T; Brouns, R; De Deyn, PP; De Surgeloose, D; Scharpé, S; Verkerk, R; Wauters, A, 2010)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brouns, R1
Verkerk, R1
Aerts, T1
De Surgeloose, D1
Wauters, A1
Scharpé, S1
De Deyn, PP1

Other Studies

1 other study available for 3-hydroxyanthranilic acid and Brain Ischemia

ArticleYear
The role of tryptophan catabolism along the kynurenine pathway in acute ischemic stroke.
    Neurochemical research, 2010, Volume: 35, Issue:9

    Topics: 3-Hydroxyanthranilic Acid; Aged; Aged, 80 and over; Brain Ischemia; Free Radical Scavengers; Humans;

2010