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3-hydroxyacetanilide and Chemical and Drug Induced Liver Injury

3-hydroxyacetanilide has been researched along with Chemical and Drug Induced Liver Injury in 5 studies

*Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment. [MeSH]

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Abdelmegeed, MA; Banerjee, A; Hardwick, JP; Jang, S; Song, BJ1
Howell, BA; Siler, SQ; Watkins, PB1
Ding, WX; Dorko, K; Du, K; Jaeschke, H; Kumer, SC; McGill, MR; Schmitt, TM; Xie, Y1

Other Studies

5 other study(ies) available for 3-hydroxyacetanilide and Chemical and Drug Induced Liver Injury

ArticleYear
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Robust protein nitration contributes to acetaminophen-induced mitochondrial dysfunction and acute liver injury.
    Free radical biology & medicine, 2013, Volume: 60

    Topics: Acetaminophen; Acetanilides; Acetylcysteine; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Mice; Mitochondria, Liver; Nitrates; Oxidative Stress; Proteins; Superoxide Dismutase

2013
Use of a systems model of drug-induced liver injury (DILIsym(®)) to elucidate the mechanistic differences between acetaminophen and its less-toxic isomer, AMAP, in mice.
    Toxicology letters, 2014, Apr-21, Volume: 226, Issue:2

    Topics: Acetaminophen; Acetanilides; Animals; Benzoquinones; Biotransformation; Chemical and Drug Induced Liver Injury; Computer Simulation; Cytochrome P-450 CYP2E1; Imines; Isomerism; Liver; Mice; Models, Biological; Systems Biology

2014
Mitochondrial protein adducts formation and mitochondrial dysfunction during N-acetyl-m-aminophenol (AMAP)-induced hepatotoxicity in primary human hepatocytes.
    Toxicology and applied pharmacology, 2015, Dec-01, Volume: 289, Issue:2

    Topics: Acetanilides; Animals; Cell Death; Cells, Cultured; Chemical and Drug Induced Liver Injury; Dose-Response Relationship, Drug; Glutamate Dehydrogenase; Glutathione; Hepatocytes; Humans; JNK Mitogen-Activated Protein Kinases; L-Lactate Dehydrogenase; Liver; Mice; Mitochondria, Liver; Mitochondrial Proteins; Phosphorylation; Primary Cell Culture; Protein Binding; Signal Transduction; Species Specificity; Time Factors

2015