3-hydroxy-3-methylglutaryl-coenzyme a and Disease Models, Animal

3-hydroxy-3-methylglutaryl-coenzyme a has been researched along with Disease Models, Animal in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (14.29)18.2507
2000's5 (35.71)29.6817
2010's7 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Arivalagan, S; Islam Siddique, A; Mani, V; Namasivayam, N1
Bahekar, R; Jain, MR; Joharapurkar, A; Kshirsagar, S; Pandey, D; Patel, D; Patel, HM; Patel, V; Shah, GB; Shah, K1
Chang, HF; Chang, JK; Chen, HT; Chuang, SC; Feng, CW; Ho, ML; Hsieh, KC; Kao, CL; Wang, GJ; Wen, ZH; Wu, SM1
Ding, Z; Klein, JD; Liang, T; Liangpunsakul, S; Lossie, AC; Lumeng, L; Morello, GM; Muir, WM; San Miguel, PJ; Sherrill, JB1
Berry, E; Fernandez-Patron, C; Hernandez-Anzaldo, S; Kassiri, Z; Takawale, A; Wang, X1
Chandra, R; Rai, SK; Sharma, M; Tiwari, M; Tiwari, RK1
Bababeygy, SR; Hou, LC; Polevaya, NV; Prugpichailers, T; Steinman, L; Sun, A; Tse, V; Veeravagu, A; Xiong, A; Youssef, S1
Anikster, Y; Bernardini, I; Burgess, HA; Ciccone, C; Dorward, H; Feldman, B; Huizing, M; Kelley, RI; Kratz, LE; Pei, W; Sood, R; Yokogawa, T1
Choi, DH; Choi, JS; Yang, SH1
Bok, SH; Choi, MS; Do, GM; Ha, TY; Jeong, KS; Lee, JS; Lee, MK; Park, HM; Woo, MN; Yeo, JY1
Bordet, R; Destée, A; Gelé, P; Kreisler, A; Lhermitte, M; Wiart, JF1
Aktas, O; Waiczies, S; Zipp, F1
Chen, TS; Ness, GC; Salen, G; Salen, L; Shefer, S; Tint, GS; Xu, G; Zhao, Z1
Aebischer, P; Bensadoun, JC; Inouye, M; Mirochnitchenko, O; Zurn, AD1

Reviews

1 review(s) available for 3-hydroxy-3-methylglutaryl-coenzyme a and Disease Models, Animal

ArticleYear
Neurodegeneration in autoimmune demyelination: recent mechanistic insights reveal novel therapeutic targets.
    Journal of neuroimmunology, 2007, Volume: 184, Issue:1-2

    Topics: Acyl Coenzyme A; Animals; Catechin; Disease Models, Animal; Encephalomyelitis, Autoimmune, Experimental; Humans; Multiple Sclerosis; Nerve Degeneration; Neuroprotective Agents; T-Lymphocytes; TNF-Related Apoptosis-Inducing Ligand

2007

Other Studies

13 other study(ies) available for 3-hydroxy-3-methylglutaryl-coenzyme a and Disease Models, Animal

ArticleYear
Antihyperlipidemic and antiapoptotic potential of zingerone on alcohol induced hepatotoxicity in experimental rats.
    Chemico-biological interactions, 2017, Jun-25, Volume: 272

    Topics: Acyl Coenzyme A; Animals; Apoptosis; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Disease Models, Animal; DNA Damage; Down-Regulation; Ethanol; Fatty Acids, Nonesterified; Guaiacol; Lipoproteins, HDL; Lipoproteins, LDL; Liver; Liver Diseases, Alcoholic; Male; Phosphatidylcholine-Sterol O-Acyltransferase; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar

2017
Central and Peripheral Glucagon Reduces Hyperlipidemia in Rats and Hamsters.
    Drug research, 2017, Volume: 67, Issue:6

    Topics: Acyl Coenzyme A; Animals; Cholesterol; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Glucagon; Hyperlipidemias; Injections, Intraventricular; Injections, Subcutaneous; Lipid Metabolism; Lipids; Liver; Male; Mesocricetus; Rats; Rats, Sprague-Dawley; Triglycerides

2017
A novel anabolic agent: a simvastatin analogue without HMG-CoA reductase inhibitory activity.
    Organic letters, 2014, Sep-05, Volume: 16, Issue:17

    Topics: Acyl Coenzyme A; Anabolic Agents; Animals; Disease Models, Animal; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Molecular Structure; Osteogenesis; Simvastatin; Solid-Phase Synthesis Techniques; Zebrafish

2014
A snapshot of the hepatic transcriptome: ad libitum alcohol intake suppresses expression of cholesterol synthesis genes in alcohol-preferring (P) rats.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Acyl Coenzyme A; Alcohol Drinking; Animals; Behavior, Animal; Choice Behavior; Cholesterol; Disease Models, Animal; Down-Regulation; Ethanol; Female; Gene Expression Profiling; Humans; Liver; Molecular Sequence Data; Rats; Sequence Analysis, RNA

2014
Matrix metalloproteinase-2 mediates a mechanism of metabolic cardioprotection consisting of negative regulation of the sterol regulatory element-binding protein-2/3-hydroxy-3-methylglutaryl-CoA reductase pathway in the heart.
    Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:4

    Topics: Acyl Coenzyme A; Animals; Blood Pressure; Cardiomegaly; Disease Models, Animal; Gene Expression Regulation; Immunoblotting; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Real-Time Polymerase Chain Reaction; RNA; Sterol Regulatory Element Binding Protein 2; Transcription Factors

2015
Effects of nitric oxide modulators on cardiovascular risk factors in mild hyperhomocysteinaemic rat model.
    Basic & clinical pharmacology & toxicology, 2008, Volume: 103, Issue:1

    Topics: Acyl Coenzyme A; Animals; Aorta, Thoracic; C-Reactive Protein; Cardiovascular Diseases; Caveolin 2; Disease Models, Animal; Hyperhomocysteinemia; Leukotrienes; Lipid Metabolism; Liver; Male; Methionine; Nitric Oxide; Nitric Oxide Donors; Nitroarginine; Nitroprusside; Oxidative Stress; Rats; Rats, Wistar; Receptors, Purinergic P2; Resistin; Risk Factors

2008
HMG-CoA reductase inhibition causes increased necrosis and apoptosis in an in vivo mouse glioblastoma multiforme model.
    Anticancer research, 2009, Volume: 29, Issue:12

    Topics: Acyl Coenzyme A; Animals; Apoptosis; Brain Neoplasms; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelium, Vascular; Glioblastoma; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoenzyme Techniques; Mice; Mice, Inbred C57BL; Necrosis; Neoplasms, Experimental; Neovascularization, Physiologic; Simvastatin

2009
A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3.
    Development (Cambridge, England), 2010, Aug-01, Volume: 137, Issue:15

    Topics: Acyl Coenzyme A; Alleles; Amino Acid Metabolism, Inborn Errors; Animals; Disease Models, Animal; Electron Transport; Glutarates; Membrane Proteins; Mitochondria; Models, Biological; Models, Genetic; Optic Atrophy; Phosphorylation; Proteins; Zebrafish; Zebrafish Proteins

2010
Effects of HMG-CoA reductase inhibitors on the pharmacokinetics of losartan and its main metabolite EXP-3174 in rats: possible role of CYP3A4 and P-gp inhibition by HMG-CoA reductase inhibitors.
    Pharmacology, 2011, Volume: 88, Issue:1-2

    Topics: Acyl Coenzyme A; Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Anticholesteremic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Injections, Intravenous; Losartan; Lovastatin; Male; Rats; Rats, Sprague-Dawley; Rhodamine 123; Simvastatin; Tetrazoles; Time Factors

2011
Supplementation of whole persimmon leaf improves lipid profiles and suppresses body weight gain in rats fed high-fat diet.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2006, Volume: 44, Issue:11

    Topics: Acyl Coenzyme A; Adipose Tissue, Brown; Animals; Cholesterol; Dietary Fats; Diospyros; Disease Models, Animal; Epididymis; Hypolipidemic Agents; Lipid Metabolism; Lipoproteins; Liver; Male; Organ Size; Plant Extracts; Plant Leaves; Rats; Rats, Sprague-Dawley; Sterol O-Acyltransferase; Triglycerides; Weight Gain

2006
Lipid-lowering drugs in the MPTP mouse model of Parkinson's disease: fenofibrate has a neuroprotective effect, whereas bezafibrate and HMG-CoA reductase inhibitors do not.
    Brain research, 2007, Mar-02, Volume: 1135, Issue:1

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Acyl Coenzyme A; Analysis of Variance; Animals; Bezafibrate; Cell Death; Disease Models, Animal; Drug Interactions; Fenofibrate; Hypolipidemic Agents; Male; Mice; Mice, Inbred C57BL; Monoamine Oxidase; MPTP Poisoning; PPAR alpha; Substantia Nigra

2007
Treatment of the cholesterol biosynthetic defect in Smith-Lemli-Opitz syndrome reproduced in rats by BM 15.766.
    Gastroenterology, 1995, Volume: 109, Issue:4

    Topics: Acyl Coenzyme A; Animals; Cholesterol; Cholic Acid; Cholic Acids; Dehydrocholesterols; Disease Models, Animal; Liver; Lovastatin; Male; Microsomes, Liver; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Piperazines; Rats; Rats, Sprague-Dawley; Smith-Lemli-Opitz Syndrome

1995
Attenuation of 6-OHDA-induced neurotoxicity in glutathione peroxidase transgenic mice.
    The European journal of neuroscience, 1998, Volume: 10, Issue:10

    Topics: Acyl Coenzyme A; Animals; Cell Count; Cell Size; Corpus Striatum; Crosses, Genetic; Disease Models, Animal; Dopamine; Glutathione Peroxidase; Humans; Injections, Intraventricular; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Neurons; Oxidation-Reduction; Oxidopamine; Parkinson Disease; Tyrosine 3-Monooxygenase

1998