3-hydroxy-3-methylglutaryl-coenzyme a and Alzheimer Disease

3-hydroxy-3-methylglutaryl-coenzyme a has been researched along with Alzheimer Disease in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Bell, AS; Jung, J; Lohoff, FW; Mavromatis, LA; Rosoff, DB; Wagner, J1
Eckert, GP; Hooff, GP; Igbavboa, U; Müller, WE; Strandjord, DM; Volmer, DA; Wood, WG1
Bryleva, EY; Buen, F; Chang, CC; Chang, TY; Harris, BT; Hickey, WF; LaFerla, FM; Oddo, S; Rogers, MA; Rousselet, E; Seidah, NG; Spencer, TA1
Distl, R; Glöckner, F; Meske, V; Ohm, TG; Schönheit, B; Tamanai, M; Treiber-Held, S1
McGeer, EG; McGeer, PL; Yasojima, K1

Other Studies

5 other study(ies) available for 3-hydroxy-3-methylglutaryl-coenzyme a and Alzheimer Disease

ArticleYear
Mendelian Randomization Study of PCSK9 and HMG-CoA Reductase Inhibition and Cognitive Function.
    Journal of the American College of Cardiology, 2022, 08-16, Volume: 80, Issue:7

    Topics: Acyl Coenzyme A; Alzheimer Disease; Cognition; Genome-Wide Association Study; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mendelian Randomization Analysis; Proprotein Convertase 9

2022
Regulation of the brain isoprenoids farnesyl- and geranylgeranylpyrophosphate is altered in male Alzheimer patients.
    Neurobiology of disease, 2009, Volume: 35, Issue:2

    Topics: Acyl Coenzyme A; Aged; Aged, 80 and over; Alzheimer Disease; Animals; Brain; Cholesterol; Farnesyltranstransferase; Frontal Lobe; Geranyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Myelin Sheath; Polyisoprenyl Phosphates; Sesquiterpenes; Simvastatin

2009
ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Feb-16, Volume: 107, Issue:7

    Topics: Acetyl-CoA C-Acetyltransferase; Acyl Coenzyme A; Alzheimer Disease; Amyloid; Animals; Brain; Cholesterol; Gene Silencing; Humans; Hydroxycholesterols; Mice; Mice, Transgenic; Models, Biological

2010
Cholesterol and tau protein--findings in Alzheimer's and Niemann Pick C's disease.
    Pharmacopsychiatry, 2003, Volume: 36 Suppl 2

    Topics: Acyl Coenzyme A; Alzheimer Disease; Analysis of Variance; Animals; Anticholesteremic Agents; Astrocytes; Blotting, Western; Brain Chemistry; Calcium; Cerebral Cortex; Cholesterol; Dextrans; Drug Interactions; Filipin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; In Situ Hybridization; Intracellular Signaling Peptides and Proteins; Lovastatin; Mevalonic Acid; Mice; Mice, Inbred BALB C; Mice, Transgenic; Microglia; Microtubules; Neurofibrillary Tangles; Neurons; Niemann-Pick C1 Protein; Niemann-Pick Diseases; Proteins; rho GTP-Binding Proteins; RNA, Messenger; tau Proteins; Tubulin

2003
3-hydroxy-3-methylglutaryl-coenzyme A reductase mRNA in Alzheimer and control brain.
    Neuroreport, 2001, Sep-17, Volume: 12, Issue:13

    Topics: Acyl Coenzyme A; Aged; Alzheimer Disease; Amyloid beta-Peptides; Brain; Brain Chemistry; Cholesterol; Heart; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney; Liver; Myocardium; Neuroprotective Agents; RNA, Messenger; Spleen

2001