3-deoxyvasicine and Bronchial-Spasm

3-deoxyvasicine has been researched along with Bronchial-Spasm* in 1 studies

Other Studies

1 other study(ies) available for 3-deoxyvasicine and Bronchial-Spasm

Article	Year
Synthesis and bronchodilatory activity of four new derivatives of deoxyvasicine. Drug design and discovery, 1996, Volume: 14, Issue:1 As part of a continuing effort aimed at the development of efficacious antihistaminic and bronchodilator agents for the treatment of asthma and related respiratory diseases, a series of novel trisubstituted deoxyvasicine derivatives was designed and synthesized. Bronchodilatory activity of pure samples of ligands 17a-d, and DL-8-chlorovasicine hydrochloride is investigated and compared with isoprenaline and aminophylline. These studies confirm the activity of ligands 17a-d and the potentiating effect of 17c on aminophylline. Topics: Alkaloids; Aminophylline; Animals; Bronchial Spasm; Bronchodilator Agents; Drug Evaluation, Preclinical; Guinea Pigs; In Vitro Techniques; Isoproterenol; Quinazolines; Structure-Activity Relationship; Trachea	1996

Article

Year

Synthesis and bronchodilatory activity of four new derivatives of deoxyvasicine.

Drug design and discovery, 1996, Volume: 14, Issue:1

As part of a continuing effort aimed at the development of efficacious antihistaminic and bronchodilator agents for the treatment of asthma and related respiratory diseases, a series of novel trisubstituted deoxyvasicine derivatives was designed and synthesized. Bronchodilatory activity of pure samples of ligands 17a-d, and DL-8-chlorovasicine hydrochloride is investigated and compared with isoprenaline and aminophylline. These studies confirm the activity of ligands 17a-d and the potentiating effect of 17c on aminophylline.

Topics: Alkaloids; Aminophylline; Animals; Bronchial Spasm; Bronchodilator Agents; Drug Evaluation, Preclinical; Guinea Pigs; In Vitro Techniques; Isoproterenol; Quinazolines; Structure-Activity Relationship; Trachea

1996