3-deoxyglucosone has been researched along with Diabetes Mellitus, Type 2 in 19 studies
*Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY. [MeSH]
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (15.79) | 18.2507 |
| 2000's | 4 (21.05) | 29.6817 |
| 2010's | 7 (36.84) | 24.3611 |
| 2020's | 5 (26.32) | 2.80 |
| Authors | Studies |
|---|---|
| Dagnelie, PC; Eussen, SJPM; Maasen, K; Opperhuizen, A; Schalkwijk, CG; Scheijen, JLJM; Stehouwer, CDA; van der Kallen, CJH; van Greevenbroek, MMJ | 1 |
| Alouffi, S; Khan, MWA | 1 |
| Ahmad, K; Choi, I; Lee, EJ; Lee, YH; Shaikh, S | 1 |
| Ahmad, S; Farooqui, A; Husain, A; Khanam, A; Rehman, S; Yusuf, MA | 1 |
| Hanssen, NMJ; Hovind, P; Parving, HH; Persson, F; Piazza, M; Rossing, P; Schalkwijk, CG; Scheijen, JL; Stehouwer, CDA; van de Waarenburg, MPH; van Greevenbroek, MMJ | 1 |
| Gao, WY; Li, H; Liu, ZF; Ma, SB; Wang, XJ | 1 |
| Gao, WY; Li, H; Wang, XJ; Zhang, HX; Zhu, AH | 1 |
| Schalkwijk, CG; Scheijen, JL | 1 |
| Hanssen, NM; Maessen, DE; Schalkwijk, CG; Scheijen, JL; Stehouwer, CD; van der Kallen, CJ; van Greevenbroek, MM | 1 |
| Bahn, G; Beisswenger, PJ; Howell, S; Reaven, PD; Saremi, A; Schwenke, DC | 1 |
| Fokkens, BT; Los, LI; Mulder, DJ; Schalkwijk, CG; Scheijen, JL; Smit, AJ | 1 |
| Barto, R; Engelen, L; Ferreira, I; Gram, J; Lund, SS; Parving, HH; Pedersen, O; Schalkwijk, CG; Stehouwer, CD; Tarnow, L; Teerlink, T; Vaag, AA; Winther, K | 1 |
| Kajita, M; Nakamura, S; Niwa, T; Tsukushi, S | 1 |
| Baynes, JW; Bleich, M; Busch, AE; Deemer, EK; Dingermann, T; Huber, J; Münch, G; Schäfer, S; Schmid, K; Somoza, V; Wihler, C | 1 |
| Beisswenger, PJ; Drummond, KS; Howell, SK; Mauer, M; Nelson, RG; Szwergold, BS | 1 |
| Araki, N; Hamada, Y; Horiuchi, S; Hotta, N | 1 |
| Beisswenger, PJ; Howell, SK; Lal, S; Szwergold, BS; Touchette, AD | 1 |
| Maeda, K; Matsumoto, Y; Odani, H; Shinzato, T; Usami, J | 1 |
| Hamada, Y; Horiuchi, S; Hotta, N; Kasuya, Y; Kato, K; Komori, T; Nagai, R; Nakamura, J; Naruse, K | 1 |
3 review(s) available for 3-deoxyglucosone and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Dicarbonyls Generation, Toxicities, Detoxifications and Potential Roles in Diabetes Complications.
Topics: Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Insulin; Insulin Resistance; Isoenzymes; Lactoylglutathione Lyase; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Signal Transduction | 2020 |
Consequences of Dicarbonyl Stress on Skeletal Muscle Proteins in Type 2 Diabetes.
Topics: Deoxyglucose; Diabetes Mellitus, Type 2; Extracellular Matrix Proteins; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Insulin; Insulin Resistance; Isoenzymes; Lactoylglutathione Lyase; Muscle, Skeletal; Oxidative Stress; Protein Carbonylation; Pyruvaldehyde; Signal Transduction | 2020 |
Glycation and Antioxidants: Hand in the Glove of Antiglycation and Natural Antioxidants.
Topics: Antigens, Neoplasm; Antioxidants; Cardiovascular Diseases; Deoxyglucose; Diabetes Mellitus, Type 2; Gene Expression Regulation; Glycation End Products, Advanced; Glyoxal; Humans; Lactoylglutathione Lyase; Mitogen-Activated Protein Kinases; Neoplasms; NF-kappa B; Oxidative Stress; Plant Extracts; Polyphenols; Protein Carbonylation; Pyruvaldehyde; Signal Transduction | 2020 |
3 trial(s) available for 3-deoxyglucosone and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Irbesartan treatment does not influence plasma levels of the dicarbonyls methylglyoxal, glyoxal and 3-deoxyglucosone in participants with type 2 diabetes and microalbuminuria: An IRMA2 sub-study.
Topics: Albuminuria; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Follow-Up Studies; Glyoxal; Humans; Irbesartan; Male; Middle Aged; Pyruvaldehyde; Tandem Mass Spectrometry; Time Factors; Treatment Outcome | 2021 |
Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes.
Topics: Carbamates; Confidence Intervals; Deoxyglucose; Diabetes Mellitus, Type 2; Humans; Hypoglycemic Agents; Metformin; Piperidines | 2011 |
Metformin reduces systemic methylglyoxal levels in type 2 diabetes.
Topics: Adult; Aged; Deoxyglucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Female; Humans; Hypoglycemic Agents; Insulin; Lactic Acid; Male; Metformin; Middle Aged; Osmolar Concentration; Pyruvaldehyde; Sulfonylurea Compounds; Treatment Outcome | 1999 |
13 other study(ies) available for 3-deoxyglucosone and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Higher habitual intake of dietary dicarbonyls is associated with higher corresponding plasma dicarbonyl concentrations and skin autofluorescence: the Maastricht Study.
Topics: Aged; Chromatography, Liquid; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diet; Diet Surveys; Dietary Exposure; Fasting; Female; Glycation End Products, Advanced; Glyoxal; Humans; Linear Models; Male; Mass Spectrometry; Middle Aged; Netherlands; Optical Imaging; Pyruvaldehyde; Skin | 2022 |
Elevated levels of α-dicarbonyl compounds in the plasma of type II diabetics and their relevance with diabetic nephropathy.
Topics: Aged; Biomarkers; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diacetyl; Female; Glyoxal; Humans; Male; Middle Aged; Pyruvaldehyde | 2019 |
Measurement of α-dicarbonyl compounds in human saliva by pre-column derivatization HPLC.
Topics: Adult; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Glyoxal; Humans; Male; Middle Aged; Pyruvaldehyde; Saliva | 2019 |
Quantification of glyoxal, methylglyoxal and 3-deoxyglucosone in blood and plasma by ultra performance liquid chromatography tandem mass spectrometry: evaluation of blood specimen.
Topics: Blood Chemical Analysis; Calibration; Chromatography, High Pressure Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glyoxal; Humans; Isotope Labeling; Perchlorates; Phenylenediamines; Pyruvaldehyde; Tandem Mass Spectrometry; Time Factors | 2014 |
Post-Glucose Load Plasma α-Dicarbonyl Concentrations Are Increased in Individuals With Impaired Glucose Metabolism and Type 2 Diabetes: The CODAM Study.
Topics: Atherosclerosis; Blood Glucose; Chromatography, Liquid; Cross-Sectional Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Fasting; Female; Glucose Tolerance Test; Glycated Hemoglobin; Glyoxal; Humans; Hyperglycemia; Male; Mass Spectrometry; Middle Aged; Postprandial Period; Pyruvaldehyde | 2015 |
Advanced Glycation End Products, Oxidation Products, and the Extent of Atherosclerosis During the VA Diabetes Trial and Follow-up Study.
Topics: Aged; Atherosclerosis; Blood Glucose; Carotid Intima-Media Thickness; Cholesterol; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycation End Products, Advanced; Humans; Imidazoles; Lysine; Male; Middle Aged; Oxidation-Reduction; Pyruvaldehyde; Triglycerides | 2017 |
Vitreous advanced glycation endproducts and α-dicarbonyls in retinal detachment patients with type 2 diabetes mellitus and non-diabetic controls.
Topics: Adult; Aged; Aged, 80 and over; Arginine; Biomarkers; Case-Control Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Retinal Detachment | 2017 |
Gas chromatographic-mass spectrometric determination of erythrocyte 3-deoxyglucosone in diabetic patients.
Topics: Adolescent; Adult; Case-Control Studies; Child; Deoxyglucose; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Erythrocytes; Female; Gas Chromatography-Mass Spectrometry; Glycated Hemoglobin; Humans; Male; Reference Standards | 2002 |
Renal accumulation and clearance of advanced glycation end-products in type 2 diabetic nephropathy: effect of angiotensin-converting enzyme and vasopeptidase inhibition.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Ascorbic Acid; Blood Glucose; Chromatography, High Pressure Liquid; Creatine; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; Glycation End Products, Advanced; Heterocyclic Compounds, 3-Ring; Kidney; Lysine; Male; Oxidation-Reduction; Protease Inhibitors; Ramipril; Rats; Rats, Zucker; Spectrometry, Fluorescence | 2005 |
Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress.
Topics: Adolescent; Adult; Cohort Studies; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Disease Susceptibility; Glycated Hemoglobin; Humans; Indians, North American; Oxidative Stress; Pyruvaldehyde; Risk Factors | 2005 |
Role of polyol pathway in nonenzymatic glycation.
Topics: Aldehyde Reductase; Animals; Cattle; Deoxyglucose; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Erythrocytes; Fructosephosphates; Glycation End Products, Advanced; Glycosylation; Humans; In Vitro Techniques; Polymers; Rhodanine; Serum Albumin, Bovine; Thiazolidines | 1996 |
Increase in three alpha,beta-dicarbonyl compound levels in human uremic plasma: specific in vivo determination of intermediates in advanced Maillard reaction.
Topics: 2-Naphthylamine; Aging; Arginine; Chromatography, Liquid; Deoxyglucose; Diabetes Mellitus, Type 2; Glycation End Products, Advanced; Glyoxal; Humans; Kidney Failure, Chronic; Lysine; Mass Spectrometry; Matched-Pair Analysis; Middle Aged; Pyruvaldehyde; Reactive Oxygen Species; Sensitivity and Specificity; Uremia | 1999 |
Epalrestat, an aldose reductase ihibitor, reduces the levels of Nepsilon-(carboxymethyl)lysine protein adducts and their precursors in erythrocytes from diabetic patients.
Topics: Aldehyde Reductase; Blood Glucose; Blood Proteins; Deoxyglucose; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Diabetic Retinopathy; Enzyme Inhibitors; Erythrocytes; Female; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Lysine; Male; Middle Aged; Reference Values; Rhodanine; Thiazolidines | 2000 |