Page last updated: 2024-08-25

3-deazaneplanocin and Neoplasms

3-deazaneplanocin has been researched along with Neoplasms in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Chandra, G; Chang, TS; Choi, S; Jang, JY; Jeong, LS; Kim, G; Lee, SK; Lee, Y; Moon, YW; Mulamoottil, VA; Nayak, A; Noh, M; Oh, K; Sahu, PK; Song, J1
Li, J; Liang, C; Liu, C; Ren, X; Tian, L; Xia, J1
Du, W; Duan, R; Guo, W1
Amin, SG; Belinsky, SA; Desai, DH; Do, K; Filipczak, PT; Hutt, JA; Juri, D; Picchi, MA; Tellez, CS1
Au, SL; Lee, JM; Ng, IO; Wong, CC; Wong, CM1
Creasy, CL; McCabe, MT1
Chai, CL; Goh, YL; Hill, J; Jiang, X; Lee, PL; Li, Z; Lim, CZ; Nguyen, TM; Ong, EH; Santhanakrishnan, S; Tam, EK; Tan, TW; Wong, SY; Yang, H; Yu, Q1
Carmona, FJ; Esteller, M; Fernandez, AF; Imai, K; Jacinto, FV; Marquez, VE; Puertas, S; Shinomura, Y; Taniguchi, H; Villanueva, A; Yamamoto, H1
Crea, F; Danesi, R; Marquez, VE; Paolicchi, E1

Reviews

4 review(s) available for 3-deazaneplanocin and Neoplasms

ArticleYear
Targeting Enhancer of Zeste Homolog 2 for the Treatment of Hematological Malignancies and Solid Tumors: Candidate Structure-Activity Relationships Insights and Evolution Prospects.
    Journal of medicinal chemistry, 2022, 05-26, Volume: 65, Issue:10

    Topics: Animals; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Hematologic Neoplasms; Histone Methyltransferases; Humans; Molecular Targeted Therapy; Neoplasms; Structure-Activity Relationship

2022
EZH2: a novel target for cancer treatment.
    Journal of hematology & oncology, 2020, 07-28, Volume: 13, Issue:1

    Topics: Adenosine; Antineoplastic Agents; Benzamides; Biphenyl Compounds; Cell Cycle; Cell Transformation, Neoplastic; Clinical Trials as Topic; Combined Modality Therapy; Drug Resistance, Neoplasm; Enhancer of Zeste Homolog 2 Protein; Epigenetic Repression; Histone Code; Histones; Humans; Methylation; Morpholines; Multicenter Studies as Topic; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Polycomb Repressive Complex 2; Pyridones; Structure-Activity Relationship; Transcriptional Activation; Tumor Microenvironment

2020
EZH2 as a potential target in cancer therapy.
    Epigenomics, 2014, Volume: 6, Issue:3

    Topics: Adenosine; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Humans; Neoplasms; Neoplastic Stem Cells; Polycomb Repressive Complex 2; Small Molecule Libraries

2014
Polycomb genes and cancer: time for clinical application?
    Critical reviews in oncology/hematology, 2012, Volume: 83, Issue:2

    Topics: Adenosine; Animals; Antineoplastic Agents; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Neoplastic Stem Cells; Polycomb Repressive Complex 2; Polycomb-Group Proteins

2012

Other Studies

5 other study(ies) available for 3-deazaneplanocin and Neoplasms

ArticleYear
Structure-Activity Relationships of Neplanocin A Analogues as S-Adenosylhomocysteine Hydrolase Inhibitors and Their Antiviral and Antitumor Activities.
    Journal of medicinal chemistry, 2015, Jun-25, Volume: 58, Issue:12

    Topics: Adenine; Adenosine; Adenosylhomocysteinase; Animals; Antineoplastic Agents; Antiviral Agents; Cell Line, Tumor; Chlorocebus aethiops; Enzyme Inhibitors; Humans; Molecular Docking Simulation; Neoplasms; Structure-Activity Relationship; Vero Cells; Virus Diseases; Viruses

2015
Chromatin remodeling by the histone methyltransferase EZH2 drives lung pre-malignancy and is a target for cancer prevention.
    Clinical epigenetics, 2021, 02-25, Volume: 13, Issue:1

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Benzamides; Biphenyl Compounds; Cell Proliferation; Chromatin Assembly and Disassembly; CpG Islands; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Epigenesis, Genetic; Epithelial Cells; Female; Histone Code; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Lung Neoplasms; Mice; Morpholines; Neoplasms; Phenotype; Pyridones; Transcriptome

2021
EZH2-Mediated H3K27me3 Is Involved in Epigenetic Repression of Deleted in Liver Cancer 1 in Human Cancers.
    PloS one, 2013, Volume: 8, Issue:6

    Topics: Actin Cytoskeleton; Adenosine; Antineoplastic Agents; Cell Line, Tumor; Cell Movement; Enhancer of Zeste Homolog 2 Protein; Epigenetic Repression; Gene Expression Regulation, Neoplastic; GTPase-Activating Proteins; Histones; Humans; Methylation; Neoplasms; Promoter Regions, Genetic; RNA, Messenger; Tumor Suppressor Proteins

2013
3-Deazaneplanocin A and neplanocin A analogues and their effects on apoptotic cell death.
    ChemMedChem, 2015, Volume: 10, Issue:1

    Topics: Adenosine; Adenosylhomocysteinase; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Enzyme Inhibitors; HCT116 Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Structure-Activity Relationship; Transplantation, Heterologous

2015
Silencing of Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer.
    Oncogene, 2012, Apr-12, Volume: 31, Issue:15

    Topics: Adenosine; Animals; Breast Neoplasms; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Female; Humans; Kruppel-Like Transcription Factors; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Polycomb Repressive Complex 2; Prostatic Neoplasms; RNA Interference; Transcription Factors; Transfection

2012