3-deazaneplanocin has been researched along with Disease Models, Animal in 15 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (6.67) | 29.6817 |
2010's | 7 (46.67) | 24.3611 |
2020's | 7 (46.67) | 2.80 |
Authors | Studies |
---|---|
Cheng, L; Hou, C; Xiao, L; Yan, N; Zhao, L; Zheng, S | 1 |
Kurata, Y; Mimura, I; Nangaku, M; Tanaka, T; Yamazaki, T | 1 |
Liu, N; Ma, X; Qiu, A; Shi, Y; Tao, M; Wang, Y; Zang, X; Zhuang, S | 1 |
Pan, YM; Rao, ZQ; Wan, SS; Yang, WJ; Yang, YN | 1 |
Liebisch, M; Wolf, G | 1 |
Chen, D; Li, H; Li, J; Lu, T; Luo, X; Ma, R; Sun, W; Wen, W; Xu, R | 1 |
Ding, C; He, F; Jiang, Y; Jin, L; Wang, H; Wang, J; Wang, L; Xiang, C; Zhang, Y; Zhao, Y; Zhong, F | 1 |
Chen, D; Cheng, L; Liu, Y; Wang, Y; Xiao, L; Yan, N; Zhang, J; Zheng, S | 1 |
Bayliss, G; Guan, Y; Tolbert, T; Zang, X; Zhao, TC; Zhou, X; Zhuang, S | 1 |
Alahmari, B; Choi, J; Cooper, M; DiPersio, JF; Ritchey, J; Ziga, E | 1 |
Chung, AY; Hui, KM; Huynh, H; Lam, PY; Lim, KH; Ooi, LL; Sia, KC | 1 |
Li, L; Rong, R; Wang, J; Xu, M; Zhu, T | 1 |
Alisi, A; Ceccarelli, S; Crudele, A; De Stefanis, C; Gaspari, S; Gnani, D; Locatelli, F; Marquez, VE; Nobili, V; Rota, R; Vella, S | 1 |
Chu, DCK; Di Paolo, D; Hardy, T; Leslie, J; Luli, S; Mann, DA; Mann, J; Mendivil, EJ; Moran Salvador, E; Oakley, F; Page, A; Perri, P; Ponzoni, M; Sabater, L; Sharkey, V; Singh, US; Tsukamoto, H; Zeybel, M | 1 |
Baker, RO; Bray, M; Geisbert, T; Raymond, JL | 1 |
15 other study(ies) available for 3-deazaneplanocin and Disease Models, Animal
Article | Year |
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DZNep protects against retinal ganglion cell death in an NMDA-induced mouse model of retinal degeneration.
Topics: Adenosine; Animals; Cell Count; Cell Death; Disease Models, Animal; Electroretinography; Intravitreal Injections; Male; Mice; N-Methylaspartate; Retinal Degeneration; Retinal Ganglion Cells | 2021 |
Dznep, a histone modification inhibitor, inhibits HIF1α binding to TIMP2 gene and suppresses TIMP2 expression under hypoxia.
Topics: Acute Kidney Injury; Adenosine; Animals; Disease Models, Animal; Epigenesis, Genetic; Histone Code; Humans; Mice; Tissue Inhibitor of Metalloproteinase-2 | 2023 |
Genetic or pharmacologic blockade of enhancer of zeste homolog 2 inhibits the progression of peritoneal fibrosis.
Topics: Adenosine; Animals; Apoptosis; Cell Movement; Cells, Cultured; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Epithelial-Mesenchymal Transition; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Peritoneal Fibrosis; Peritoneum; RNA Interference; RNA, Small Interfering; Signal Transduction | 2020 |
Inhibition of EZH2 alleviates angiogenesis in a model of corneal neovascularization by blocking FoxO3a-mediated oxidative stress.
Topics: Adenosine; Animals; Cells, Cultured; Corneal Neovascularization; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Forkhead Box Protein O3; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Oxidative Stress; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; RNA, Small Interfering; Signal Transduction; Transcription, Genetic | 2020 |
AGE-Induced Suppression of EZH2 Mediates Injury of Podocytes by Reducing H3K27me3.
Topics: Adenosine; Animals; Cell Line; Diabetic Nephropathies; Disease Models, Animal; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Epigenesis, Genetic; Glycation End Products, Advanced; Humans; Intracellular Signaling Peptides and Proteins; Mice; Podocytes; RNA, Small Interfering | 2020 |
DZNep attenuates allergic airway inflammation in an ovalbumin-induced murine model.
Topics: Adenosine; Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Cytokines; Disease Models, Animal; Female; Hypersensitivity; Inflammation; Lung; Mice; Mice, Inbred BALB C; Ovalbumin | 2021 |
Histone H3K27 methyltransferase EZH2 and demethylase JMJD3 regulate hepatic stellate cells activation and liver fibrosis.
Topics: Adenosine; Animals; Apoptosis; Benzazepines; Bile Ducts; Carbon Tetrachloride; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Proliferation; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Enzyme Inhibitors; Hepatic Stellate Cells; Humans; Indoles; Interleukin-10; Jumonji Domain-Containing Histone Demethylases; Ligation; Liver; Liver Cirrhosis; Mice; Pyridones; Pyrimidines; Rats; RNA Interference | 2021 |
DZNep inhibits H3K27me3 deposition and delays retinal degeneration in the rd1 mice.
Topics: Adenosine; Amino Acid Motifs; Animals; Calpain; Disease Models, Animal; Epigenesis, Genetic; Female; Histones; Humans; Lysine; Male; Methylation; Mice; Mice, Inbred ICR; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Retina; Retinal Degeneration | 2018 |
Targeting enhancer of zeste homolog 2 protects against acute kidney injury.
Topics: Acute Kidney Injury; Adenosine; Adherens Junctions; Animals; Apoptosis; Cadherins; Cells, Cultured; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Epithelial Cells; Folic Acid; Hydrogen Peroxide; Jumonji Domain-Containing Histone Demethylases; Kidney; Kidney Tubules; Lipocalin-2; Male; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Phosphatidylethanolamine Binding Protein; Phosphorylation; Proto-Oncogene Proteins c-raf; Reperfusion Injury; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinase-3; Zonula Occludens-1 Protein | 2018 |
Selective targeting of histone modification fails to prevent graft versus host disease after hematopoietic cell transplantation.
Topics: Adenosine; Animals; Benzamides; Biphenyl Compounds; Cells, Cultured; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Graft vs Host Disease; Hematopoietic Stem Cell Transplantation; Histone Code; Histones; Humans; Indoles; Methylation; Mice; Morpholines; Pyridones; T-Lymphocytes | 2018 |
Preclinical evaluation of transcriptional targeting strategy for human hepatocellular carcinoma in an orthotopic xenograft mouse model.
Topics: Adenosine; Animals; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression; Genetic Therapy; Genetic Vectors; Humans; Liver Neoplasms; Mice; Regulatory Sequences, Nucleic Acid; Transcription, Genetic; Transgenes; Xenograft Model Antitumor Assays | 2013 |
Modulation of allogeneic CD8+ T-cell response by DZNep controls GVHD while preserving hematopoietic chimerism.
Topics: Adenosine; Animals; Apoptosis; Cell Proliferation; Disease Models, Animal; Enzyme Inhibitors; Fas Ligand Protein; Female; Graft vs Host Disease; Granzymes; Hematopoietic Stem Cell Transplantation; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-2; Lymphocyte Activation; Male; Methylation; Mice; Mice, Inbred C3H; T-Lymphocytes, Cytotoxic; Time Factors; TNF-Related Apoptosis-Inducing Ligand; Transplantation Chimera; Transplantation Tolerance; Transplantation, Homologous; Tumor Necrosis Factor-alpha | 2013 |
EZH2 down-regulation exacerbates lipid accumulation and inflammation in in vitro and in vivo NAFLD.
Topics: Adenosine; Animals; Disease Models, Animal; Down-Regulation; Enhancer of Zeste Homolog 2 Protein; Fatty Liver; Hep G2 Cells; Histones; Humans; MicroRNAs; Non-alcoholic Fatty Liver Disease; Oleic Acid; Palmitic Acid; Polycomb Repressive Complex 2; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2013 |
A Proof-of-Concept for Epigenetic Therapy of Tissue Fibrosis: Inhibition of Liver Fibrosis Progression by 3-Deazaneplanocin A.
Topics: Adenosine; Animals; Biomarkers; Carbon Tetrachloride; Collagen Type I; Disease Models, Animal; Disease Progression; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation; Hepatic Stellate Cells; Histone Methyltransferases; Histone-Lysine N-Methyltransferase; Histones; Liver Cirrhosis; Male; Mice; Myofibroblasts | 2017 |
3-deazaneplanocin A induces massively increased interferon-alpha production in Ebola virus-infected mice.
Topics: Adenosine; Animals; Disease Models, Animal; Ebolavirus; Female; Hemorrhagic Fever, Ebola; Immunohistochemistry; Interferon-alpha; Liver; Mice; Mice, Inbred BALB C; Viremia | 2002 |