3-deazaneplanocin has been researched along with Breast Cancer in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 4 (57.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Clermont, PL; Crea, F; Fornaro, L | 1 |
| Chen, F; Deng, L; Mo, Q; Song, Y; Wei, L; Wu, B; Yao, Y; Zhang, L | 1 |
| Cornelissen-Steijger, P; Drost, R; Evers, B; Jonkers, J; Joosse, SA; Liu, X; Nederlof, P; Pietersen, AM; Puppe, J; van Lohuizen, M; Yu, Q | 1 |
| Chan, E; Marquez, VE; Sun, F; Wu, Z; Yang, X; Yu, Q | 1 |
| Crabb, SJ; Hayden, A; Johnson, PW; Packham, G | 1 |
| Carmona, FJ; Esteller, M; Fernandez, AF; Imai, K; Jacinto, FV; Marquez, VE; Puertas, S; Shinomura, Y; Taniguchi, H; Villanueva, A; Yamamoto, H | 1 |
| Chen, W; Jiang, X; Karuturi, RK; Lee, PL; Liu, ET; Tan, J; Tan, PB; Yang, X; Yu, Q; Zhuang, L | 1 |
7 other study(ies) available for 3-deazaneplanocin and Breast Cancer
| Article | Year |
|---|---|
Elevated expression of a pharmacologic Polycomb signature predicts poor prognosis in gastric and breast cancer.
Topics: Adenosine; Biomarkers, Tumor; Breast Neoplasms; Cell Line, Tumor; Female; Humans; Male; Polycomb-Group Proteins; Stomach Neoplasms; Survival Analysis; Up-Regulation | 2017 |
Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer.
Topics: Adenosine; Animals; Apoptosis; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Differentiation; Cell Movement; Cell Proliferation; DNA Methylation; Enzyme Inhibitors; Female; Flow Cytometry; Histone-Lysine N-Methyltransferase; Histones; Humans; Immunoenzyme Techniques; Lysine; Methyltransferases; Mice; Mice, Nude; Neoplastic Stem Cells; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2014 |
BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A.
Topics: Adenosine; Animals; BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; DNA Repair; Drug Delivery Systems; Enhancer of Zeste Homolog 2 Protein; Female; Gene Knockdown Techniques; Genes, BRCA1; Histone-Lysine N-Methyltransferase; Humans; Mice; Mutation; Polycomb Repressive Complex 2; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; RNA, Small Interfering | 2009 |
Combinatorial pharmacologic approaches target EZH2-mediated gene repression in breast cancer cells.
Topics: Adenosine; Antigens, Neoplasm; Azacitidine; Breast Neoplasms; Cell Line; Cell Line, Tumor; Chromatin Immunoprecipitation; Cluster Analysis; CpG Islands; Decitabine; DNA Methylation; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone Deacetylase Inhibitors; Histones; Humans; Hydroxamic Acids; Immunoblotting; Methylation; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Polycomb Repressive Complex 2; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Transcription Factors | 2009 |
S-adenosylhomocysteine hydrolase inhibition by 3-deazaneplanocin A analogues induces anti-cancer effects in breast cancer cell lines and synergy with both histone deacetylase and HER2 inhibition.
Topics: Adenosine; Adenosylhomocysteinase; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cytoplasm; Drug Synergism; Female; Histone Deacetylase Inhibitors; Humans; Lipid Metabolism; Protein Kinase Inhibitors; Receptor, ErbB-2 | 2011 |
Silencing of Kruppel-like factor 2 by the histone methyltransferase EZH2 in human cancer.
Topics: Adenosine; Animals; Breast Neoplasms; DNA-Binding Proteins; Enhancer of Zeste Homolog 2 Protein; Female; Humans; Kruppel-Like Transcription Factors; Male; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Polycomb Repressive Complex 2; Prostatic Neoplasms; RNA Interference; Transcription Factors; Transfection | 2012 |
Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells.
Topics: Adenosine; Adenosylhomocysteinase; Apoptosis; Base Sequence; Breast Neoplasms; Cell Line, Tumor; Chromatin Assembly and Disassembly; Chromatin Immunoprecipitation; Enzyme Inhibitors; Epigenesis, Genetic; Female; Histones; Humans; Methylation; Polycomb-Group Proteins; Promoter Regions, Genetic; Repressor Proteins; RNA Interference; RNA Polymerase II; RNA, Small Interfering | 2007 |