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3-carboxy-4-methyl-5-propyl-2-furanpropionic acid and Kidney Failure, Chronic

3-carboxy-4-methyl-5-propyl-2-furanpropionic acid has been researched along with Kidney Failure, Chronic in 18 studies

*Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION. [MeSH]

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19904 (22.22)18.7374
1990's7 (38.89)18.2507
2000's5 (27.78)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Asaba, H; Deguchi, T; Mori, S; Ohtsuki, S; Otagiri, M; Takanaga, H; Terasaki, T1
Furukubo, T; Hiraoka, S; Hosoda, S; Izumi, S; Minegaki, T; Miyoshi, A; Nagano, Y; Nishiguchi, K; Shiraishi, A; Tsujimoto, M; Yamakawa, T1
Kawai, K; Nishii, R; Nishio, T; Takamura, N; Tokunaga, J; Yoshimoto, M1
Arkouche, W; Bouchara, A; Fouque, D; Granjon, S; Koppe, L; Laville, M; Luce, M; Pastural, M; Soulage, CO; Szelag, JC1
Hirata, S; Kinoshita, Y; Ohtani, H; Otagiri, M; Sawada, Y; Tsujimoto, M1
Benet, LZ; Frassetto, L; Huang, Y; Lin, ET; Sun, H1
Liebich, HM; Pickert, A; Tetschner, B1
Bernard, BF; de Jong, M; Docter, R; Hennemann, G; Krenning, EP; Lim, CF1
Costigan, MG; Lindup, WE; Yaqoob, M1
Niwa, T1
Callaghan, CA; Costigan, MG; Lindup, WE1
Maruyama, T; Otagiri, M; Shimada, H; Takadate, A; Tsutsumi, Y1
Mabuchi, H; Nakahashi, H3
Bubeck, JI; Liebich, HM; Pickert, A; Scheiter, A; Wahl, G1
Eggstein, M; Fischer, U; Liebich, HM; Rapp, K; Risler, T; Tetschner, B1
Maeda, K; Tsuruta, Y1

Reviews

1 review(s) available for 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid and Kidney Failure, Chronic

ArticleYear
Organic acids and the uremic syndrome: protein metabolite hypothesis in the progression of chronic renal failure.
    Seminars in nephrology, 1996, Volume: 16, Issue:3

    Topics: Animals; Furans; Hippurates; Humans; Indoles; Kidney Failure, Chronic; Propionates; Protein Binding; Proteins; Rats

1996

Trials

2 trial(s) available for 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid and Kidney Failure, Chronic

ArticleYear
Influences of haemodialysis on the binding sites of human serum albumin: possibility of an efficacious administration plan using binding inhibition.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:7

    Topics: Adult; Aged; Barbiturates; Binding Sites; Carbon Radioisotopes; Diazepam; Diuretics; Fatty Acids, Nonesterified; Female; Furans; Furosemide; Hippurates; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Propionates; Protein Binding; Renal Dialysis; Serum Albumin; Treatment Outcome; Warfarin

2008
Hypothesis: is accumulation of a furan dicarboxylic acid (3-carboxy-4- methyl-5-propyl-2-furanpropanoic acid) related to the neurological abnormalities in patients with renal failure?
    Nephron, 1996, Volume: 73, Issue:2

    Topics: Furans; Humans; Kidney Failure, Chronic; Nervous System Diseases; Peritoneal Dialysis, Continuous Ambulatory; Propionates; Renal Dialysis

1996

Other Studies

15 other study(ies) available for 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid and Kidney Failure, Chronic

ArticleYear
Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney.
    Kidney international, 2002, Volume: 61, Issue:5

    Topics: Animals; Anions; Biological Transport; Dose-Response Relationship, Drug; Female; Furans; Indican; Kidney; Kidney Failure, Chronic; Male; Oocytes; Organic Anion Transporters, Sodium-Independent; p-Aminohippuric Acid; Probenecid; Propionates; Rats; Rats, Wistar; Toxins, Biological; Tritium; Uremia; Uricosuric Agents; Xenopus laevis

2002
Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease.
    Toxins, 2013, Aug-19, Volume: 5, Issue:8

    Topics: Cell Line, Tumor; Cytochrome P-450 CYP3A; Erythromycin; Furans; Hippurates; Humans; Indican; Indoleacetic Acids; Kidney Failure, Chronic; Liver; Microsomes, Liver; Pregnane X Receptor; Propionates; Receptors, Calcitriol; Receptors, Steroid; RNA, Messenger; Steroid Hydroxylases; Toxins, Biological; Vitamin D; Vitamin D3 24-Hydroxylase

2013
Is 3-Carboxy-4-methyl-5-propyl-2-furanpropionate (CMPF) a Clinically Relevant Uremic Toxin in Haemodialysis Patients?
    Toxins, 2018, 05-18, Volume: 10, Issue:5

    Topics: Aged; Female; Furans; Humans; Kidney Failure, Chronic; Male; Middle Aged; Nutritional Status; Propionates; Renal Dialysis; Toxins, Biological; Uremia

2018
Effects of uremic serum and uremic toxins on hepatic uptake of digoxin.
    Therapeutic drug monitoring, 2008, Volume: 30, Issue:5

    Topics: Animals; Biological Transport, Active; Cresols; Digoxin; Dose-Response Relationship, Drug; Furans; Hepatocytes; Humans; Kidney Failure, Chronic; Liver; Male; Propionates; Rats; Rats, Sprague-Dawley; Renal Dialysis; Uremia

2008
Liquid chromatographic tandem mass spectrometric assay for the uremic toxin 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid in human plasma.
    Rapid communications in mass spectrometry : RCM, 2006, Volume: 20, Issue:10

    Topics: Adult; Calibration; Chromatography, Liquid; Female; Furans; Humans; Kidney Failure, Chronic; Male; Propionates; Solvents; Spectrophotometry, Ultraviolet; Tandem Mass Spectrometry; Uremia

2006
Gas chromatographic and gas chromatographic-mass spectrometric analysis of organic acids in plasma of patients with chronic renal failure.
    Journal of chromatography, 1984, Apr-27, Volume: 289

    Topics: Adolescent; Adult; Aged; Carboxylic Acids; Chromatography, Gas; Female; Furans; Gas Chromatography-Mass Spectrometry; Hippurates; Humans; Kidney Failure, Chronic; Male; Middle Aged; Propionates; Renal Dialysis

1984
A furan fatty acid and indoxyl sulfate are the putative inhibitors of thyroxine hepatocyte transport in uremia.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:2

    Topics: Adsorption; Animals; Biological Transport; Cells, Cultured; Furans; Hippurates; Humans; Indican; Iodides; Kidney Failure, Chronic; Liver; Male; Propionates; Rats; Rats, Wistar; Renal Dialysis; Thyroxine; Uremia

1993
Retention of an albumin-bound furan dicarboxylic acid in patients with chronic renal failure or after a kidney transplant.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1996, Volume: 11, Issue:5

    Topics: Adult; Aged; Biomarkers; Case-Control Studies; Creatinine; Female; Furans; Hemoglobins; Humans; Kidney Failure, Chronic; Kidney Transplantation; Kidney Tubules; Male; Middle Aged; Propionates; Protein Binding; Serum Albumin

1996
Decreased bilirubin-binding capacity in uremic serum caused by an accumulation of furan dicarboxylic acid.
    Nephron, 2000, Volume: 85, Issue:1

    Topics: Adult; Bilirubin; Furans; Humans; Indican; Kidney Failure, Chronic; Male; Middle Aged; Propionates; Protein Binding; Serum Albumin; Uremia

2000
Separation of albumin-binding ligands present in uremic serum by high-performance affinity chromatography.
    Journal of chromatography, 1990, Aug-03, Volume: 529, Issue:2

    Topics: Chromatography, Affinity; Chromatography, High Pressure Liquid; Furans; Humans; Kidney Failure, Chronic; Ligands; Propionates; Protein Binding; Renal Dialysis; Serum Albumin; Spectrophotometry, Ultraviolet; Uremia

1990
Hippuric acid and 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid in serum and urine. Analytical approaches and clinical relevance in kidney diseases.
    Journal of chromatography, 1990, Feb-02, Volume: 500

    Topics: Chromatography, Gas; Chromatography, High Pressure Liquid; Furans; Hemofiltration; Hippurates; Humans; Kidney Failure, Chronic; Propionates; Reference Values; Renal Dialysis

1990
Endogenous ligands that bind to serum albumin and renal failure.
    Nephron, 1990, Volume: 55, Issue:1

    Topics: Furans; Humans; Kidney Failure, Chronic; Propionates; Protein Binding; Serum Albumin

1990
Gas chromatographic determination of hippuric acid and a furancarboxylic acid in plasma of patients with kidney diseases.
    Journal of chromatography, 1987, Jul-24, Volume: 399

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Creatinine; Female; Furans; Hippurates; Humans; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Propionates; Protein Binding; Renal Dialysis; Time Factors

1987
A major endogenous ligand substance involved in renal failure.
    Nephron, 1988, Volume: 49, Issue:4

    Topics: Acute Kidney Injury; Creatinine; Furans; Hemoperfusion; Humans; Kidney Failure, Chronic; Plasma Exchange; Propionates; Renal Dialysis

1988
[Pathologic change of serum albumin in chronic renal failure: human mercapt/nonmercaptoalbumin and endogenous drug binding inhibitor].
    Rinsho byori. The Japanese journal of clinical pathology, 1987, Volume: 35, Issue:9

    Topics: Furans; Humans; Kidney Failure, Chronic; Propionates; Protein Binding; Serum Albumin

1987