3-aminobenzamide has been researched along with Osteosarcoma in 4 studies
Osteosarcoma: A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we investigate the effects of 3-aminobenzamide (3-AB), a potent inhibitor of PARP, on human osteosarcoma cells and whether or not it can sensitize the tumor cells to chemotherapeutic agents." | 7.77 | The poly(ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide suppresses cell growth and migration, enhancing suppressive effects of cisplatin in osteosarcoma cells. ( Peng, F; Wu, H; Xu, XQ; Yu, JZ; Zheng, YD, 2011) |
| "A novel cancer stem-like cell line (3AB-OS), expressing a number of pluripotent stem cell markers, was irreversibly selected from human osteosarcoma MG-63 cells by long-term treatment (100 days) with 3-aminobenzamide (3AB)." | 7.75 | Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment. ( De Blasio, A; Di Fiore, R; Ferrante, RD; Giuliano, M; Messina, C; Pirozzi, G; Santulli, A; Tesoriere, G; Tirino, V; Vento, R, 2009) |
| "This study demonstrates that in human osteosarcoma cells treatment with 3-aminobenzamide (3-AB), a potent inhibitor of poly(ADP-ribose) polymerase (PARP), induces morphological and biochemical features of differentiation, the duration of which depends on whether or not the normal RB gene is expressed." | 7.72 | The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells. ( D'Anneo, A; De Blasio, A; Emanuele, S; Giuliano, M; Lauricella, M; Musmeci, MT; Tesoriere, G; Vassallo, B; Vento, R, 2003) |
| " In the present study, we investigate the effects of 3-aminobenzamide (3-AB), a potent inhibitor of PARP, on human osteosarcoma cells and whether or not it can sensitize the tumor cells to chemotherapeutic agents." | 3.77 | The poly(ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide suppresses cell growth and migration, enhancing suppressive effects of cisplatin in osteosarcoma cells. ( Peng, F; Wu, H; Xu, XQ; Yu, JZ; Zheng, YD, 2011) |
| "A novel cancer stem-like cell line (3AB-OS), expressing a number of pluripotent stem cell markers, was irreversibly selected from human osteosarcoma MG-63 cells by long-term treatment (100 days) with 3-aminobenzamide (3AB)." | 3.75 | Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment. ( De Blasio, A; Di Fiore, R; Ferrante, RD; Giuliano, M; Messina, C; Pirozzi, G; Santulli, A; Tesoriere, G; Tirino, V; Vento, R, 2009) |
| "This study demonstrates that in human osteosarcoma cells treatment with 3-aminobenzamide (3-AB), a potent inhibitor of poly(ADP-ribose) polymerase (PARP), induces morphological and biochemical features of differentiation, the duration of which depends on whether or not the normal RB gene is expressed." | 3.72 | The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells. ( D'Anneo, A; De Blasio, A; Emanuele, S; Giuliano, M; Lauricella, M; Musmeci, MT; Tesoriere, G; Vassallo, B; Vento, R, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Di Fiore, R | 1 |
| Santulli, A | 2 |
| Ferrante, RD | 1 |
| Giuliano, M | 2 |
| De Blasio, A | 3 |
| Messina, C | 2 |
| Pirozzi, G | 1 |
| Tirino, V | 1 |
| Tesoriere, G | 3 |
| Vento, R | 3 |
| Zheng, YD | 1 |
| Xu, XQ | 1 |
| Peng, F | 1 |
| Yu, JZ | 1 |
| Wu, H | 1 |
| Musmeci, MT | 1 |
| Lauricella, M | 1 |
| Emanuele, S | 1 |
| D'Anneo, A | 2 |
| Vassallo, B | 1 |
| Mangano, V | 1 |
| Di Leonardo, E | 1 |
4 other studies available for 3-aminobenzamide and Osteosarcoma
| Article | Year |
|---|---|
Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment.
Topics: Adolescent; Adult; Apoptosis; ATP-Binding Cassette Transporters; Benzamides; Benzimidazoles; Biomark | 2009 |
The poly(ADP-ribose) polymerase-1 inhibitor 3-aminobenzamide suppresses cell growth and migration, enhancing suppressive effects of cisplatin in osteosarcoma cells.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; Cell Movement; Cell Proliferation; C | 2011 |
The effect of 3-aminobenzamide, inhibitor of poly(ADP-ribose) polymerase, on human osteosarcoma cells.
Topics: Alkaline Phosphatase; Apoptosis; bcl-2-Associated X Protein; Benzamides; Blotting, Western; Caspase | 2003 |
Differentiative pathway activated by 3-aminobenzamide, an inhibitor of PARP, in human osteosarcoma MG-63 cells.
Topics: Adenosine Diphosphate Ribose; Base Sequence; Benzamides; Blotting, Western; Cell Cycle Proteins; Cel | 2005 |