3-aminobenzamide has been researched along with Necrosis in 28 studies
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Necrosis has been classified into subtypes based on the active molecular players and parthanatos is one among them, which is characterized by the over activation of PARP1 as the pre-mitochondrial event that triggers necrosis." | 5.46 | JNK1 and JNK3 play a significant role in both neuronal apoptosis and necrosis. Evaluation based on in vitro approach using tert-butylhydroperoxide induced oxidative stress in neuro-2A cells and perturbation through 3-aminobenzamide. ( Chandrasekar, K; Michael, FM; Muthaiah, VPK; Palaniappan, T; Rajan, SS; Venkatachalam, S, 2017) |
| "Programmed necrosis is important in many (patho)physiological settings." | 1.40 | TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death. ( Adam, D; Chan, FK; Davarnia, P; Herdegen, T; Kabelitz, D; Lange, A; Linkermann, A; Mathieu, S; Rittger, A; Schütze, S; Sosna, J; Thon, L; Voigt, S, 2014) |
| "A paucity of cancer in individuals with Alzheimer's disease (AD) and low rates of AD in cancer survivors has been reported in epidemiological studies." | 1.38 | Inverse susceptibility to oxidative death of lymphocytes obtained from Alzheimer's patients and skin cancer survivors: increased apoptosis in Alzheimer's and reduced necrosis in cancer. ( Behrens, MI; Merino, D; Ponce, DP; Quest, AF; Roe, CM; Salech, F; Silva, M; Sinning, M; Xiong, C, 2012) |
| "NO-induced CMC necrosis is likely mediated by PARP activation which occurs as a consequence of caspase activation." | 1.31 | Nitric oxide induces caspase-dependent apoptosis and necrosis in neonatal rat cardiomyocytes. ( Imamura, H; Kido, M; Kobayashi, Y; Ninomiya, H; Nogi, S; Okada, T; Otani, H; Uchiyama, T, 2002) |
| " Furthermore, chronic administration of 0." | 1.27 | Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD+ ADP ribosyl transferase in rats. ( Denda, A; Emi, Y; Konishi, Y; Mikami, S; Nakae, D; Ohnishi, T; Takahashi, S; Yokose, Y, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.14) | 18.7374 |
| 1990's | 7 (25.00) | 18.2507 |
| 2000's | 13 (46.43) | 29.6817 |
| 2010's | 6 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sosna, J | 1 |
| Voigt, S | 1 |
| Mathieu, S | 1 |
| Lange, A | 1 |
| Thon, L | 1 |
| Davarnia, P | 1 |
| Herdegen, T | 1 |
| Linkermann, A | 1 |
| Rittger, A | 1 |
| Chan, FK | 1 |
| Kabelitz, D | 1 |
| Schütze, S | 1 |
| Adam, D | 1 |
| Zhao, H | 1 |
| Ning, J | 1 |
| Lemaire, A | 1 |
| Koumpa, FS | 1 |
| Sun, JJ | 1 |
| Fung, A | 1 |
| Gu, J | 1 |
| Yi, B | 1 |
| Lu, K | 1 |
| Ma, D | 1 |
| Muthaiah, VPK | 1 |
| Michael, FM | 1 |
| Palaniappan, T | 1 |
| Rajan, SS | 1 |
| Chandrasekar, K | 1 |
| Venkatachalam, S | 1 |
| Makogon, N | 1 |
| Voznesenskaya, T | 1 |
| Bryzgina, T | 1 |
| Sukhina, V | 1 |
| Grushka, N | 1 |
| Alexeyeva, I | 1 |
| Behrens, MI | 1 |
| Silva, M | 1 |
| Salech, F | 1 |
| Ponce, DP | 1 |
| Merino, D | 1 |
| Sinning, M | 1 |
| Xiong, C | 1 |
| Roe, CM | 1 |
| Quest, AF | 1 |
| Lakatos, P | 1 |
| Szabó, É | 1 |
| Hegedűs, C | 1 |
| Haskó, G | 1 |
| Gergely, P | 1 |
| Bai, P | 1 |
| Virág, L | 1 |
| Uchiyama, T | 1 |
| Otani, H | 1 |
| Okada, T | 1 |
| Ninomiya, H | 1 |
| Kido, M | 1 |
| Imamura, H | 1 |
| Nogi, S | 1 |
| Kobayashi, Y | 1 |
| Troyano, A | 1 |
| Sancho, P | 2 |
| Fernández, C | 2 |
| de Blas, E | 2 |
| Bernardi, P | 1 |
| Aller, P | 2 |
| Darmon, D | 1 |
| Goldfarb, M | 1 |
| Shina, A | 1 |
| Rosen, S | 1 |
| Heyman, SN | 1 |
| Cover, C | 1 |
| Fickert, P | 1 |
| Knight, TR | 1 |
| Fuchsbichler, A | 1 |
| Farhood, A | 1 |
| Trauner, M | 1 |
| Jaeschke, H | 1 |
| Azuara, D | 1 |
| Sola, A | 1 |
| Hotter, G | 1 |
| Calatayud, L | 1 |
| de Oca, J | 1 |
| Csordas, A | 1 |
| Wick, G | 1 |
| Bernhard, D | 1 |
| Yuste, VJ | 1 |
| Amrán, D | 1 |
| Ramos, AM | 1 |
| Susin, SA | 1 |
| Kehe, K | 1 |
| Raithel, K | 1 |
| Kreppel, H | 1 |
| Jochum, M | 1 |
| Worek, F | 1 |
| Thiermann, H | 1 |
| Yap, E | 1 |
| Tan, WL | 1 |
| Ng, I | 1 |
| Ng, YK | 1 |
| Takahashi, S | 1 |
| Nakae, D | 1 |
| Yokose, Y | 1 |
| Emi, Y | 1 |
| Denda, A | 1 |
| Mikami, S | 1 |
| Ohnishi, T | 1 |
| Konishi, Y | 1 |
| Watson, AJ | 1 |
| Askew, JN | 1 |
| Benson, RS | 1 |
| Palomba, L | 2 |
| Sestili, P | 2 |
| Cattabeni, F | 1 |
| Azzi, A | 1 |
| Cantoni, O | 2 |
| Saldeen, J | 1 |
| Welsh, N | 1 |
| Chatterjee, PK | 1 |
| Cuzzocrea, S | 1 |
| Thiemermann, C | 1 |
| Filipovic, DM | 1 |
| Meng, X | 1 |
| Reeves, WB | 1 |
| Columbaro, M | 1 |
| Falcieri, E | 1 |
| Weise, J | 1 |
| Isenmann, S | 1 |
| Bähr, M | 1 |
| Grusch, M | 1 |
| Polgar, D | 1 |
| Gfatter, S | 1 |
| Leuhuber, K | 1 |
| Huettenbrenner, S | 1 |
| Leisser, C | 1 |
| Fuhrmann, G | 1 |
| Kassie, F | 1 |
| Steinkellner, H | 1 |
| Smid, K | 1 |
| Peters, GJ | 1 |
| Jayaram, HN | 1 |
| Klepal, W | 1 |
| Szekeres, T | 1 |
| Knasmüller, S | 1 |
| Krupitza, G | 1 |
| Harel, A | 1 |
| Bloch, O | 1 |
| Vardi, P | 1 |
| Bloch, K | 1 |
| Cole, KK | 1 |
| Perez-Polo, JR | 1 |
| Holme, JA | 1 |
| Søderlund, J | 1 |
| Låg, M | 1 |
| Brunborg, G | 1 |
| Dybing, E | 1 |
| Chen, G | 1 |
| Pan, QC | 1 |
28 other studies available for 3-aminobenzamide and Necrosis
| Article | Year |
|---|---|
TNF-induced necroptosis and PARP-1-mediated necrosis represent distinct routes to programmed necrotic cell death.
Topics: Animals; Antineoplastic Agents, Alkylating; Apoptosis; Benzamides; Calpain; Cathepsins; Cell Line; C | 2014 |
Necroptosis and parthanatos are involved in remote lung injury after receiving ischemic renal allografts in rats.
Topics: Acute Lung Injury; Animals; Benzamides; Cells, Cultured; Culture Media, Conditioned; Cyclosporine; D | 2015 |
JNK1 and JNK3 play a significant role in both neuronal apoptosis and necrosis. Evaluation based on in vitro approach using tert-butylhydroperoxide induced oxidative stress in neuro-2A cells and perturbation through 3-aminobenzamide.
Topics: Animals; Apoptosis; Benzamides; Caspase 3; Cell Line, Tumor; Cell Survival; DNA Fragmentation; Gene | 2017 |
Poly(ADP-ribose) polymerase inhibitor, 3-aminobenzamide, protects against experimental immune ovarian failure in mice.
Topics: Animals; Apoptosis; Benzamides; Enzyme Inhibitors; Female; Meiosis; Mice; Mice, Inbred CBA; Necrosis | 2010 |
Inverse susceptibility to oxidative death of lymphocytes obtained from Alzheimer's patients and skin cancer survivors: increased apoptosis in Alzheimer's and reduced necrosis in cancer.
Topics: Aged; Aged, 80 and over; Aging; Alzheimer Disease; Apoptosis; Benzamides; Case-Control Studies; Cell | 2012 |
3-Aminobenzamide protects primary human keratinocytes from UV-induced cell death by a poly(ADP-ribosyl)ation independent mechanism.
Topics: Apoptosis; Benzamides; Blotting, Western; Caspases; Cell Proliferation; Cells, Cultured; Enzyme Acti | 2013 |
Nitric oxide induces caspase-dependent apoptosis and necrosis in neonatal rat cardiomyocytes.
Topics: Animals; Apoptosis; Benzamides; Caspase 3; Caspases; Cytochrome c Group; Mitochondria; Myocytes, Car | 2002 |
The selection between apoptosis and necrosis is differentially regulated in hydrogen peroxide-treated and glutathione-depleted human promonocytic cells.
Topics: Adenosine Triphosphate; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Benzamides; Blotting, | 2003 |
Effect of poly(ADP-ribose) polymerase inhibition on outer medullary hypoxic damage.
Topics: Acute Kidney Injury; Animals; Benzamides; Contrast Media; Disease Models, Animal; Disease Progressio | 2003 |
Pathophysiological role of poly(ADP-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Benzamides; Biotransformation; Chemical and Drug I | 2005 |
Apoptosis inhibition plays a greater role than necrosis inhibition in decreasing bacterial translocation in experimental intestinal transplantation.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Bacterial Translocation; Benzamides; Caspase 3; | 2005 |
Hydrogen peroxide-mediated necrosis induction in HUVECs is associated with an atypical pattern of caspase-3 cleavage.
Topics: Amino Acid Chloromethyl Ketones; Benzamides; Caspase 3; Caspase 7; Caspase Inhibitors; Caspases; Cel | 2006 |
Regulation of apoptosis/necrosis execution in cadmium-treated human promonocytic cells under different forms of oxidative stress.
Topics: Acetylcysteine; Adenosine Triphosphate; Antimetabolites, Antineoplastic; Apoptosis; Benzamides; Buth | 2006 |
Inhibition of poly(ADP-ribose) polymerase (PARP) influences the mode of sulfur mustard (SM)-induced cell death in HaCaT cells.
Topics: Adenosine Triphosphate; Antimetabolites; Apoptosis; Benzamides; Bromodeoxyuridine; Carcinogens; Cell | 2008 |
Combinatorial-approached neuroprotection using pan-caspase inhibitor and poly (ADP-ribose) polymerase (PARP) inhibitor following experimental stroke in rats; is there additional benefit?
Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Benzamides; Caspases; C | 2008 |
Enhancement of DEN initiation of liver carcinogenesis by inhibitors of NAD+ ADP ribosyl transferase in rats.
Topics: Animals; Benzamides; Diethylnitrosamine; DNA Repair; gamma-Glutamyltransferase; Liver; Liver Neoplas | 1984 |
Poly(adenosine diphosphate ribose) polymerase inhibition prevents necrosis induced by H2O2 but not apoptosis.
Topics: Aminobenzoates; Apoptosis; Benzamides; Cell Count; Cell Line; DNA Repair; Humans; Hydrogen Peroxide; | 1995 |
Prevention of necrosis and activation of apoptosis in oxidatively injured human myeloid leukemia U937 cells.
Topics: Apoptosis; Benzamides; Cell Line; Culture Media; DNA, Neoplasm; Enzyme Inhibitors; Humans; Hydrogen | 1996 |
Nicotinamide-induced apoptosis in insulin producing cells is associated with cleavage of poly(ADP-ribose) polymerase.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Benzamides; Cell Line; Cysteine Proteinase Inhi | 1998 |
Inhibitors of poly (ADP-ribose) synthetase protect rat proximal tubular cells against oxidant stress.
Topics: Animals; Benzamides; Catalase; Cells, Cultured; Deferoxamine; DNA Damage; Enzyme Activation; Enzyme | 1999 |
Inhibition of PARP prevents oxidant-induced necrosis but not apoptosis in LLC-PK1 cells.
Topics: Animals; Apoptosis; Benzamides; DNA Damage; Enzyme Inhibitors; Kidney Tubules, Proximal; LLC-PK1 Cel | 1999 |
Apoptosis and necrosis following exposure of U937 cells to increasing concentrations of hydrogen peroxide: the effect of the poly(ADP-ribose)polymerase inhibitor 3-aminobenzamide.
Topics: Adenine Nucleotides; Apoptosis; Benzamides; DNA; DNA Fragmentation; Drug Interactions; Enzyme Inhibi | 1999 |
Increased expression and activation of poly(ADP-ribose) polymerase (PARP) contribute to retinal ganglion cell death following rat optic nerve transection.
Topics: Animals; Axotomy; Benzamides; Brain Injuries; Cell Count; Cell Death; Cell Survival; Female; Gene Ex | 2001 |
Maintenance of ATP favours apoptosis over necrosis triggered by benzamide riboside.
Topics: Adenosine; Adenosine Triphosphate; Antineoplastic Agents; Apoptosis; Benzamides; Comet Assay; Deoxya | 2002 |
Sensitivity of HaCat keratinocytes to diabetogenic toxins.
Topics: Alloxan; Analysis of Variance; Apoptosis; Benzamides; Cell Line; Cell Survival; Enzyme Inhibitors; G | 2002 |
Poly(ADP-ribose) polymerase inhibition prevents both apoptotic-like delayed neuronal death and necrosis after H(2)O(2) injury.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Benzamides; Caspase 3; Caspases; Cell Death; Cell Surviv | 2002 |
Prevention of 1,2-dibromo-3-chloropropane (DBCP)-induced kidney necrosis and testicular atrophy by 3-aminobenzamide.
Topics: Animals; Atrophy; Benzamides; DNA Damage; DNA Replication; Ethylene Dibromide; Kidney; Male; NAD; Ne | 1991 |
Potentiation of the antitumor activity of cisplatin in mice by 3-aminobenzamide and nicotinamide.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Carcinoma, Ehrlich Tumor; Cispl | 1988 |