3-aminobenzamide has been researched along with Innate Inflammatory Response in 14 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to investigate the treatment effects and molecular mechanism of 3-aminobenzamide (3-AB) on intracranial aneurysms (IA)." | 7.91 | 3-Aminobenzamide protects against cerebral artery injury and inflammation in rats with intracranial aneurysms. ( Li, KQ; Sun, ZY; Wei, L; Yang, C; Zhong, CL, 2019) |
| "This study aimed to investigate the treatment effects and molecular mechanism of 3-aminobenzamide (3-AB) on intracranial aneurysms (IA)." | 3.91 | 3-Aminobenzamide protects against cerebral artery injury and inflammation in rats with intracranial aneurysms. ( Li, KQ; Sun, ZY; Wei, L; Yang, C; Zhong, CL, 2019) |
| "Airway inflammation is a central feature of asthma and chronic obstructive pulmonary disease." | 1.32 | Gene knockout or pharmacological inhibition of poly(ADP-ribose) polymerase-1 prevents lung inflammation in a murine model of asthma. ( Boulares, AH; Jolly, P; Massaro, D; Sherif, ZA; Smulson, ME; Zoltoski, AJ, 2003) |
| "After 60 min of hypothermic cardiac arrest, reperfusion was started after application of either saline vehicle (control, n = 6), or INO-1001 (1 mg/kg), a potent PARP inhibitor (n = 6)." | 1.32 | INO-1001 a novel poly(ADP-ribose) polymerase (PARP) inhibitor improves cardiac and pulmonary function after crystalloid cardioplegia and extracorporal circulation. ( Bährle, S; Cziráki, A; Flechtenmacher, C; Gries, A; Hagl, S; Heger, U; Mandera, S; Seres, L; Soós, P; Szabó, C; Szabó, G; Vahl, CF; Zsengellér, Z, 2004) |
| "Since inflammation is associated with oncosis and not apoptosis, the results presented here could explain the beneficial effects seen with PARP inhibition in various in vivo models of oxidant injury and provide a mechanism to manipulate this injury into a state of cell death that could ultimately be controlled." | 1.30 | Poly(ADP-ribose) polymerase inhibition in oxidant-stressed endothelial cells prevents oncosis and permits caspase activation and apoptosis. ( Thies, RL; Walisser, JA, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (28.57) | 18.2507 |
| 2000's | 7 (50.00) | 29.6817 |
| 2010's | 3 (21.43) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wei, L | 1 |
| Yang, C | 1 |
| Li, KQ | 1 |
| Zhong, CL | 1 |
| Sun, ZY | 1 |
| Komirishetty, P | 1 |
| Areti, A | 1 |
| Yerra, VG | 1 |
| Ruby, PK | 1 |
| Sharma, SS | 1 |
| Gogoi, R | 1 |
| Sistla, R | 1 |
| Kumar, A | 1 |
| Jacewicz, M | 1 |
| Czapski, GA | 2 |
| Katkowska, I | 1 |
| Strosznajder, RP | 1 |
| Boulares, AH | 1 |
| Zoltoski, AJ | 1 |
| Sherif, ZA | 1 |
| Jolly, P | 1 |
| Massaro, D | 1 |
| Smulson, ME | 1 |
| Kiefmann, R | 1 |
| Heckel, K | 1 |
| Schenkat, S | 1 |
| Dörger, M | 1 |
| Wesierska-Gadek, J | 1 |
| Goetz, AE | 1 |
| Koh, SH | 1 |
| Park, Y | 1 |
| Song, CW | 1 |
| Kim, JG | 1 |
| Kim, K | 1 |
| Kim, J | 1 |
| Kim, MH | 1 |
| Lee, SR | 1 |
| Kim, DW | 1 |
| Yu, HJ | 1 |
| Chang, DI | 1 |
| Hwang, SJ | 1 |
| Kim, SH | 1 |
| Cakala, M | 1 |
| Gajkowska, B | 1 |
| Strosznajder, JB | 1 |
| Szabó, C | 4 |
| Lim, LH | 1 |
| Cuzzocrea, S | 3 |
| Getting, SJ | 1 |
| Zingarelli, B | 3 |
| Flower, RJ | 1 |
| Salzman, AL | 2 |
| Perretti, M | 1 |
| Gilad, E | 1 |
| Hake, P | 1 |
| Costantino, G | 1 |
| Caputi, AP | 1 |
| Walisser, JA | 1 |
| Thies, RL | 1 |
| Waldman, M | 1 |
| Nudelman, V | 1 |
| Shainberg, A | 1 |
| Abraham, NG | 1 |
| Kornwoski, R | 1 |
| Aravot, D | 1 |
| Arad, M | 1 |
| Hochhauser, E | 1 |
| Murthy, KG | 1 |
| Xiao, CY | 1 |
| Mabley, JG | 1 |
| Chen, M | 1 |
| Szabó, G | 1 |
| Soós, P | 1 |
| Mandera, S | 1 |
| Heger, U | 1 |
| Flechtenmacher, C | 1 |
| Bährle, S | 1 |
| Seres, L | 1 |
| Cziráki, A | 1 |
| Gries, A | 1 |
| Zsengellér, Z | 1 |
| Vahl, CF | 1 |
| Hagl, S | 1 |
14 other studies available for 3-aminobenzamide and Innate Inflammatory Response
| Article | Year |
|---|---|
3-Aminobenzamide protects against cerebral artery injury and inflammation in rats with intracranial aneurysms.
Topics: Animals; Antigens, CD; Arterial Pressure; Benzamides; Cerebral Arterial Diseases; Inflammation; Intr | 2019 |
PARP inhibition attenuates neuroinflammation and oxidative stress in chronic constriction injury induced peripheral neuropathy.
Topics: Animals; Benzamides; Constriction, Pathologic; Cyclooxygenase 2; Hyperalgesia; Inflammation; Male; N | 2016 |
Systemic administration of lipopolysaccharide impairs glutathione redox state and object recognition in male mice. The effect of PARP-1 inhibitor.
Topics: Analysis of Variance; Animals; Benzamides; Cerebral Cortex; Cognition; Enzyme Inhibitors; Explorator | 2009 |
Gene knockout or pharmacological inhibition of poly(ADP-ribose) polymerase-1 prevents lung inflammation in a murine model of asthma.
Topics: Allergens; Animals; Asthma; Benzamides; Cell Line; Enzyme Inhibitors; Gene Expression; Humans; Hydro | 2003 |
Platelet-endothelial cell interaction in pulmonary micro-circulation: the role of PARS.
Topics: Animals; Benzamides; Blood Platelets; Cell Communication; Endothelium, Vascular; Endotoxemia; Inflam | 2004 |
The effect of PARP inhibitor on ischaemic cell death, its related inflammation and survival signals.
Topics: Animals; Benzamides; Blotting, Western; Brain; Brain Edema; Brain Infarction; Brain Ischemia; Caspas | 2004 |
Poly(ADP-ribose) polymerase-1 inhibition protects the brain against systemic inflammation.
Topics: Animals; Benzamides; Brain; Inflammation; Lipopolysaccharides; Mice; Microscopy, Electron; Poly (ADP | 2006 |
Inhibition of poly (ADP-ribose) synthetase attenuates neutrophil recruitment and exerts antiinflammatory effects.
Topics: Animals; Benzamides; Carrageenan; Cell Movement; Edema; Enzyme Inhibitors; Histocytochemistry; Infla | 1997 |
Protective effects of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthase in a carrageenan-induced model of local inflammation.
Topics: Animals; Anti-Inflammatory Agents; Benzamides; Carrageenan; Enzyme Inhibitors; Exudates and Transuda | 1998 |
Protective effects of poly (ADP-ribose) synthase inhibitors in zymosan-activated plasma induced paw edema.
Topics: Animals; Benzamides; Complement Activation; Dose-Response Relationship, Drug; Edema; Enzyme Inhibito | 1999 |
Poly(ADP-ribose) polymerase inhibition in oxidant-stressed endothelial cells prevents oncosis and permits caspase activation and apoptosis.
Topics: Animals; Apoptosis; Aurintricarboxylic Acid; Benzamides; Caspase 3; Caspases; Cattle; Cell Death; Ce | 1999 |
PARP-1 inhibition protects the diabetic heart through activation of SIRT1-PGC-1α axis.
Topics: Animals; Cells, Cultured; Diabetic Cardiomyopathies; Enzyme Inhibitors; Glucose; Heart; Hypertension | 2018 |
Activation of poly(ADP-ribose) polymerase in circulating leukocytes during myocardial infarction.
Topics: Animals; Blotting, Western; Cell Line, Tumor; DNA; DNA Damage; Enzyme Activation; Enzyme Inhibitors; | 2004 |
INO-1001 a novel poly(ADP-ribose) polymerase (PARP) inhibitor improves cardiac and pulmonary function after crystalloid cardioplegia and extracorporal circulation.
Topics: Acetylcholine; Adenosine Diphosphate Ribose; Animals; Disease Models, Animal; Dogs; Enzyme Inhibitor | 2004 |