Page last updated: 2024-10-21

3-aminobenzamide and Glioma

3-aminobenzamide has been researched along with Glioma in 3 studies

Glioma: Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21)

Research Excerpts

ExcerptRelevanceReference
"Temozolomide (TZM) is a novel methylating agent currently under investigation for treatment of recurrent high-grade gliomas."7.71Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells. ( Graziani, G; Navarra, P; Portarena, I; Scerrati, M; Tentori, L; Torino, F, 2002)
" Here, we examined the effects of 3-aminobenzamide, a poly(ADP-ribose) polymerase inhibitor, on the chemosensitivity of human malignant glioma cells."7.70Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells. ( Weller, M; Winter, S, 2000)
"Temozolomide (TZM) is a novel methylating agent currently under investigation for treatment of recurrent high-grade gliomas."3.71Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells. ( Graziani, G; Navarra, P; Portarena, I; Scerrati, M; Tentori, L; Torino, F, 2002)
" Here, we examined the effects of 3-aminobenzamide, a poly(ADP-ribose) polymerase inhibitor, on the chemosensitivity of human malignant glioma cells."3.70Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells. ( Weller, M; Winter, S, 2000)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tentori, L1
Portarena, I1
Torino, F1
Scerrati, M1
Navarra, P1
Graziani, G1
Winter, S1
Weller, M1
Lee, YW1
Ha, MS1
Kim, YK1

Other Studies

3 other studies available for 3-aminobenzamide and Glioma

ArticleYear
Poly(ADP-ribose) polymerase inhibitor increases growth inhibition and reduces G(2)/M cell accumulation induced by temozolomide in malignant glioma cells.
    Glia, 2002, Volume: 40, Issue:1

    Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Brain

2002
Poly(ADP-ribose) polymerase-independent potentiation of nitrosourea cytotoxicity by 3-aminobenzamide in human malignant glioma cells.
    European journal of pharmacology, 2000, Jun-16, Volume: 398, Issue:2

    Topics: Benzamides; Binding Sites; Carmustine; Cell Survival; Dose-Response Relationship, Drug; Drug Synergi

2000
H2O2-induced cell death in human glioma cells: role of lipid peroxidation and PARP activation.
    Neurochemical research, 2001, Volume: 26, Issue:4

    Topics: Benzamides; Brain Neoplasms; Cell Death; Dithiothreitol; Enzyme Activation; Enzyme Inhibitors; Free

2001