3-aminobenzamide has been researched along with Cerebral Infarction in 6 studies
Cerebral Infarction: The formation of an area of NECROSIS in the CEREBRUM caused by an insufficiency of arterial or venous blood flow. Infarcts of the cerebrum are generally classified by hemisphere (i.e., left vs. right), lobe (e.g., frontal lobe infarction), arterial distribution (e.g., INFARCTION, ANTERIOR CEREBRAL ARTERY), and etiology (e.g., embolic infarction).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The authors examined whether genetic deletion of PARP (PARP null mice) or its pharmacologic inhibition by 3-aminobenzamide (3-AB) attenuates tissue injury after transient cerebral ischemia." | 3.69 | Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase. ( Endres, M; Moskowitz, MA; Namura, S; Waeber, C; Wang, ZQ, 1997) |
| "However, in cerebral ischemia, excessive PARS activation may lead to energy depletion and exacerbation of neuronal damage." | 1.31 | Poly(ADP-ribose) synthase inhibition reduces ischemic injury and inflammation in neonatal rat brain. ( Ben-Ari, Y; Benjelloun, N; Charriaut-Marlangue, C; Ducrocq, S; Plotkine, M, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hortobágyi, T | 1 |
| Görlach, C | 1 |
| Benyó, Z | 1 |
| Lacza, Z | 1 |
| Hortobágyi, S | 1 |
| Wahl, M | 1 |
| Harkany, T | 1 |
| Yap, E | 1 |
| Tan, WL | 1 |
| Ng, I | 1 |
| Ng, YK | 1 |
| Endres, M | 1 |
| Wang, ZQ | 1 |
| Namura, S | 1 |
| Waeber, C | 1 |
| Moskowitz, MA | 1 |
| Tokime, T | 1 |
| Nozaki, K | 1 |
| Sugino, T | 1 |
| Kikuchi, H | 1 |
| Hashimoto, N | 1 |
| Ueda, K | 1 |
| Ducrocq, S | 1 |
| Benjelloun, N | 1 |
| Plotkine, M | 1 |
| Ben-Ari, Y | 1 |
| Charriaut-Marlangue, C | 1 |
| Ding, Y | 1 |
| Zhou, Y | 1 |
| Lai, Q | 1 |
| Li, J | 1 |
| Gordon, V | 1 |
| Diaz, FG | 1 |
6 other studies available for 3-aminobenzamide and Cerebral Infarction
| Article | Year |
|---|---|
Inhibition of neuronal nitric oxide synthase-mediated activation of poly(ADP-ribose) polymerase in traumatic brain injury: neuroprotection by 3-aminobenzamide.
Topics: Animals; Benzamides; Brain Injuries; Cerebral Infarction; Cold Temperature; Down-Regulation; Drug In | 2003 |
Combinatorial-approached neuroprotection using pan-caspase inhibitor and poly (ADP-ribose) polymerase (PARP) inhibitor following experimental stroke in rats; is there additional benefit?
Topics: Adenosine Triphosphate; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Benzamides; Caspases; C | 2008 |
Ischemic brain injury is mediated by the activation of poly(ADP-ribose)polymerase.
Topics: Animals; Benzamides; Brain; Brain Damage, Chronic; Brain Ischemia; Cerebral Infarction; DNA Damage; | 1997 |
Enhanced poly(ADP-ribosyl)ation after focal ischemia in rat brain.
Topics: Animals; Benzamides; Cerebral Infarction; Enzyme Inhibitors; Immunohistochemistry; Indazoles; Ischem | 1998 |
Poly(ADP-ribose) synthase inhibition reduces ischemic injury and inflammation in neonatal rat brain.
Topics: Animals; Animals, Newborn; Benzamides; Brain Ischemia; Cell Death; Cerebral Infarction; Encephalitis | 2000 |
Long-term neuroprotective effect of inhibiting poly(ADP-ribose) polymerase in rats with middle cerebral artery occlusion using a behavioral assessment.
Topics: Animals; Benzamides; Cerebral Infarction; Cerebrovascular Circulation; Enzyme Inhibitors; Female; In | 2001 |