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3-aminobenzamide and Cell Transformation, Neoplastic

3-aminobenzamide has been researched along with Cell Transformation, Neoplastic in 18 studies

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research Excerpts

ExcerptRelevanceReference
"3-Aminobenzamide, a potent inhibitor of nuclear poly ADP-ribosyl synthetase, was tested for its ability to alter the toxic and/or transforming effects of ethyl methanesulfonate, methyl methanesulfonate and 3-methylcholanthrene in BALB/3T3 clone A31-1 cells."1.27Effect of 3-aminobenzamide on the induction of toxicity and transformation by ethyl methanesulfonate and methylcholanthrene in BALB/3T3 cells. ( Lubet, RA; McCarvill, JT; Putman, DL; Schechtman, LM; Schwartz, JL, 1984)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199012 (66.67)18.7374
1990's3 (16.67)18.2507
2000's1 (5.56)29.6817
2010's2 (11.11)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tomasetti, M1
Amati, M1
Nocchi, L1
Saccucci, F1
Strafella, E1
Staffolani, S1
Tarquini, LM1
Carbonari, D1
Alleva, R1
Borghi, B1
Neuzil, J1
Bracci, M1
Santarelli, L1
DonĂ , F1
Chiodi, I1
Belgiovine, C1
Raineri, T1
Ricotti, R1
Mondello, C1
Scovassi, AI1
Pant, MC1
Liao, XY1
Lu, Q1
Molloi, S1
Elmore, E1
Redpath, JL1
Lubet, RA3
McCarvill, JT2
Putman, DL2
Schwartz, JL3
Schechtman, LM2
Borek, C4
Ong, A2
Morgan, WF1
Cleaver, JE4
Kurian, P1
Kumari, HL1
Milo, GE1
Nagao, M1
Nakayasu, M1
Aonuma, S1
Shima, H1
Sugimura, T1
Su, ZZ1
Zhang, PQ1
Fisher, PB1
Diamond, AM1
Der, CJ1
De Kok, AJ1
Sips, H1
Den Engelse, L1
Simons, JW1
Banda, MJ1
Troll, W1
Kasid, UN1
Stefanik, DF1
Dritschilo, A1
Smulson, ME1
Tanakura, Y1
Jan, KY1
Huang, RY1
Lee, TC1
Oleinick, NL1
Evans, HH1

Reviews

2 reviews available for 3-aminobenzamide and Cell Transformation, Neoplastic

ArticleYear
Poly(ADP-ribosylation) and neoplastic transformation: effect of PARP inhibitors.
    Current pharmaceutical biotechnology, 2013, Volume: 14, Issue:5

    Topics: Animals; Benzamides; Cell Transformation, Neoplastic; Humans; Neoplasms; Poly(ADP-ribose) Polymerase

2013
Poly(ADP-ribose) and the response of cells to ionizing radiation.
    Radiation research, 1985, Volume: 101, Issue:1

    Topics: Animals; Benzamides; Cell Cycle; Cell Survival; Cell Transformation, Neoplastic; Chromosome Aberrati

1985

Other Studies

16 other studies available for 3-aminobenzamide and Cell Transformation, Neoplastic

ArticleYear
Asbestos exposure affects poly(ADP-ribose) polymerase-1 activity: role in asbestos-induced carcinogenesis.
    Mutagenesis, 2011, Volume: 26, Issue:5

    Topics: Aged; Asbestos; Benzamides; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; DNA Damag

2011
Mechanisms of suppression of neoplastic transformation in vitro by low doses of low LET radiation.
    Carcinogenesis, 2003, Volume: 24, Issue:12

    Topics: Antioxidants; Benzamides; Buthionine Sulfoximine; Cell Line; Cell Transformation, Neoplastic; DNA Re

2003
Effect of 3-aminobenzamide on the induction of toxicity and transformation by ethyl methanesulfonate and methylcholanthrene in BALB/3T3 cells.
    Carcinogenesis, 1984, Volume: 5, Issue:4

    Topics: Animals; Benzamides; Cell Transformation, Neoplastic; Cells, Cultured; DNA Repair; Drug Interactions

1984
Inhibition of X-ray- and ultraviolet light-induced transformation in vitro by modifiers of poly(ADP-ribose) synthesis.
    Radiation research, 1984, Volume: 99, Issue:2

    Topics: Animals; Benzamides; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; DNA Repair; Mesoc

1984
Methylating and ethylating carcinogens have different requirements for poly(ADP-ribose) synthesis during malignant transformation.
    Carcinogenesis, 1984, Volume: 5, Issue:12

    Topics: Alkylating Agents; Animals; Benzamides; Carcinogens; Cell Transformation, Neoplastic; DNA Repair; Me

1984
Selective inhibition of the BPDE-I-induced modification of the replicating DNA of S-phase cells, by benzamide and 3-aminobenzamide.
    Carcinogenesis, 1992, Volume: 13, Issue:3

    Topics: Benzamides; Benzopyrenes; Cell Transformation, Neoplastic; DNA; Fibroblasts; Humans; S Phase

1992
Loss of amplified genes by poly(ADP-ribose) polymerase inhibitors.
    Environmental health perspectives, 1991, Volume: 93

    Topics: 3T3 Cells; Aminobenzoates; Animals; Benzamides; Benzoates; Benzoic Acid; Cell Differentiation; Cell

1991
Enhancement of viral and DNA mediated transformation of cloned rat embryo fibroblast cells by 3-aminobenzamide.
    Molecular carcinogenesis, 1990, Volume: 3, Issue:5

    Topics: Adenoviridae; Animals; Benzamides; Blotting, Southern; Cell Adhesion; Cell Division; Cell Line; Cell

1990
Alterations in transformation efficiency by the ADPRT-inhibitor 3-aminobenzamide are oncogene specific.
    Carcinogenesis, 1989, Volume: 10, Issue:2

    Topics: Benzamides; Cell Line; Cell Transformation, Neoplastic; Cell Transformation, Viral; Oncogenes; Simia

1989
Prolonged in vitro exposure of Syrian hamster embryo cells to 3-aminobenzamide induces transformation and chromosomal alterations but not gene mutations.
    Carcinogenesis, 1989, Volume: 10, Issue:2

    Topics: Animals; Benzamides; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Crice

1989
Effects of 3-aminobenzamide on the induction of morphologic transformation by diverse compounds in Balb/3T3 cells in vitro.
    Carcinogenesis, 1986, Volume: 7, Issue:1

    Topics: Aflatoxin B1; Aflatoxins; Animals; Benzamides; Carcinogens; Cell Transformation, Neoplastic; Cells,

1986
Some protease inhibitors are also inhibitors of poly(ADP-ribose) polymerase.
    Carcinogenesis, 1986, Volume: 7, Issue:2

    Topics: Antipain; Benzamides; Caffeine; Cell Transformation, Neoplastic; Cells, Cultured; Humans; Lymphocyte

1986
Relationship between DNA strand breaks and inhibition of poly (ADP-ribosylation): enhancement of carcinogen-induced transformation.
    Carcinogenesis, 1986, Volume: 7, Issue:2

    Topics: Animals; Base Sequence; Benzamides; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured;

1986
Roles of poly(ADP-ribose) in chemical neoplastic transformation and differentiation of C3H10T1/2 cells.
    The Kobe journal of medical sciences, 1986, Volume: 32, Issue:1

    Topics: Animals; Benzamides; Cell Line; Cell Transformation, Neoplastic; DNA, Neoplasm; Mice; Nucleoside Dip

1986
Different modes of action of sodium arsenite, 3-aminobenzamide, and caffeine on the enhancement of ethyl methanesulfonate clastogenicity.
    Cytogenetics and cell genetics, 1986, Volume: 41, Issue:4

    Topics: Animals; Arsenic; Arsenites; Benzamides; Caffeine; Cell Cycle; Cell Line; Cell Transformation, Neopl

1986
Antagonistic action of a tumor promoter and a poly(adenosine diphosphoribose) synthesis inhibitor in radiation-induced transformation in vitro.
    Biochemical and biophysical research communications, 1986, Feb-13, Volume: 134, Issue:3

    Topics: Animals; Benzamides; Carcinogens; Cell Transformation, Neoplastic; Clone Cells; DNA, Neoplasm; Fibro

1986