Page last updated: 2024-10-21

3-aminobenzamide and Ataxia Telangiectasia

3-aminobenzamide has been researched along with Ataxia Telangiectasia in 5 studies

Ataxia Telangiectasia: An autosomal recessive inherited disorder characterized by choreoathetosis beginning in childhood, progressive CEREBELLAR ATAXIA; TELANGIECTASIS of CONJUNCTIVA and SKIN; DYSARTHRIA; B- and T-cell immunodeficiency, and RADIOSENSITIVITY to IONIZING RADIATION. Affected individuals are prone to recurrent sinobronchopulmonary infections, lymphoreticular neoplasms, and other malignancies. Serum ALPHA-FETOPROTEINS are usually elevated. (Menkes, Textbook of Child Neurology, 5th ed, p688) The gene for this disorder (ATM) encodes a cell cycle checkpoint protein kinase and has been mapped to chromosome 11 (11q22-q23).

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19903 (60.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Smith, PJ2
Seong, J1
Suh, CO1
Kim, GE1
Marecki, JC1
McCord, JM1
Anderson, CO1
Watson, JV1
Painter, RB1

Other Studies

5 other studies available for 3-aminobenzamide and Ataxia Telangiectasia

ArticleYear
Relationship between a chromatin anomaly in ataxia-telangiectasia cells and enhanced sensitivity to DNA damage.
    Carcinogenesis, 1984, Volume: 5, Issue:10

    Topics: Ataxia Telangiectasia; Benzamides; Benzimidazoles; Cell Cycle; Cell Line; Chromatin; DNA; Humans

1984
Adaptive response to ionizing radiation induced by low doses of gamma rays in human cell lines.
    International journal of radiation oncology, biology, physics, 1995, Nov-01, Volume: 33, Issue:4

    Topics: Adaptation, Physiological; Ataxia Telangiectasia; Benzamides; Carcinoma, Hepatocellular; Cell Line,

1995
The inhibition of poly(ADP-ribose) polymerase enhances growth rates of ataxia telangiectasia cells.
    Archives of biochemistry and biophysics, 2002, Jun-15, Volume: 402, Issue:2

    Topics: Adenosine Triphosphate; Ataxia Telangiectasia; Benzamides; Blotting, Western; Cell Division; Cells,

2002
Abnormal retention of X-irradiated ataxia-telangiectasia fibroblasts in G2 phase of the cell cycle: cellular RNA content, chromatin stability and the effects of 3-aminobenzamide.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1985, Volume: 47, Issue:6

    Topics: Ataxia Telangiectasia; Benzamides; Cell Line; Cell Survival; Cell Transformation, Viral; Chromatin;

1985
3-Aminobenzamide does not affect radiation-induced inhibition of DNA synthesis in human cells.
    Mutation research, 1985, Volume: 143, Issue:3

    Topics: Ataxia Telangiectasia; Benzamides; Cells, Cultured; DNA; Fibroblasts; Humans; Radiation Tolerance

1985