3-aminobenzamide has been researched along with Abnormalities, Autosome in 39 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Human lymphocytes from normal and Down syndrome (DS) subjects were examined to determine the effect of 3-aminobenzamide (3AB) on X-ray-induced chromosome aberrations." | 7.67 | The effect of 3-aminobenzamide on X-ray induction of chromosome aberrations in Down syndrome lymphocytes. ( Au, WW; Legator, MS; MacLaren, RA, 1989) |
| "Human lymphocytes from normal and Down syndrome (DS) subjects were examined to determine the effect of 3-aminobenzamide (3AB) on X-ray-induced chromosome aberrations." | 3.67 | The effect of 3-aminobenzamide on X-ray induction of chromosome aberrations in Down syndrome lymphocytes. ( Au, WW; Legator, MS; MacLaren, RA, 1989) |
| "Under the same experimental conditions, chromosome aberrations were induced by AM which mainly represented chromatid-type aberrations." | 1.29 | The molecular nature of mutations induced by adriamycin at the hprt locus of V79 cells. ( Gerland, E; Helbig, R; Speit, G, 1994) |
| "Caffeine enhanced chromosome aberrations more in G2 irradiation than in S irradiation, and the frequency of chromatid-type aberrations was remarkably enhanced in G2 irradiation." | 1.29 | Radiosensitivity and effects of repair inhibitors for X-ray-induced chromosomal damage in mouse zygotes in S and G2 phases. ( Matsuda, Y; Tobari, I, 1995) |
| "A marginal increase in the frequency of chromosome aberrations was observed following treatment with 3-AB in controls as well as in patient groups." | 1.28 | Effect of inhibitor of poly (ADP-ribose) polymerase in blood lymphocyte cultures of untreated leprosy patients. ( D'Souza, D; Das, BC; Thomas, IM, 1992) |
| "Most of the induced chromosome aberrations were chromosome-type aberrations, the frequency of chromosome fragments being the highest, followed by chromosome exchanges in both sperm and oocytes." | 1.28 | Changes in X-ray sensitivity of mouse eggs from fertilization to the early pronuclear stage, and their repair capacity. ( Matsuda, Y; Seki, N; Tobari, I; Utsugi-Takeuchi, T, 1989) |
| "A high frequency of chromosome aberrations was induced in early spermatozoa to mid spermatids, while few chromosome aberrations were observed in early spermatids to late spermatocytes." | 1.28 | Mechanism of chromosome aberration induction in the mouse egg fertilized with sperm recovered from postmeiotic germ cells treated with methyl methanesulfonate. ( Maemori, M; Matsuda, Y; Seki, N; Tobari, I, 1989) |
| "The induction of chromosome aberrations by exposing sperm or oocytes to X-rays was remarkably potentiated by post-treatment incubation in the presence of each of the 3 inhibitors." | 1.28 | Repair capacity of fertilized mouse eggs for X-ray damage induced in sperm and mature oocytes. ( Matsuda, Y; Tobari, I, 1989) |
| "Caffeine was found to potentiate the frequency of chromatid aberrations induced by all 3 S-dependent agents tested; the most striking enhancement being obtained when caffeine was present during the last 1." | 1.27 | Influence of caffeine and 3-aminobenzamide in G2 on the frequency of chromosomal aberrations induced by thiotepa, mitomycin C and N-methyl-N-nitro-N'-nitrosoguanidine in human lymphocytes. ( Hansson, K; Kihlman, BA; Palitti, F; Tanzarella, C, 1984) |
| "Measurements of chromosomal aberrations induced in the labelled female cells and unlabelled male cells that had been co-cultured show that the adaptive response is restricted to those cells exposed to radiation from the incorporation of [3H]dThd and that diffusible factors are not involved." | 1.27 | Evidence that the [3H]thymidine-induced adaptive response of human lymphocytes to subsequent doses of X-rays involves the induction of a chromosomal repair mechanism. ( Afzal, V; Olivieri, G; Wiencke, JK; Wolff, S, 1986) |
| "Ring chromosomes were not lost over time as rapidly as predicted by the SCE frequencies observed." | 1.27 | Spontaneous and 3-aminobenzamide-induced sister-chromatid exchange frequencies estimated by ring chromosome analysis. ( Bodycote, J; Doida, Y; Fero, ML; Hahn, P; Kapp, LN; Morgan, WF, 1986) |
| "3AB increases the frequency of chromosomal aberrations induced by DMS, EMS, ENU, bleomycin and CldUrd." | 1.27 | Effects of 3-aminobenzamide on Chinese hamster cells treated with thymidine analogues and DNA-damaging agents. Chromosomal aberrations, mutations and cell-cycle progression. ( Darroudi, F; Hansson, K; Natarajan, AT; van Zeeland, AA; Zwanenburg, TS, 1985) |
| "The induction of chromosomal aberrations and sister-chromatid exchanges (SCEs) by short-wave ultraviolet (UV) and X-irradiation was studied in Chinese hamster ovary (CHO) wild-type (WT) cells and one of its UV-hypersensitive mutants, 43-3B." | 1.27 | Cytological characterization of repair-deficient CHO cell line 43-3B. I. Induction of chromosomal aberrations and sister-chromatid exchanges by UV and its modulation with 3-aminobenzamide. ( Darroudi, F; Natarajan, AT, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (66.67) | 18.7374 |
| 1990's | 8 (20.51) | 18.2507 |
| 2000's | 2 (5.13) | 29.6817 |
| 2010's | 3 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yadav, L | 1 |
| Khan, S | 1 |
| Shekh, K | 1 |
| Jena, GB | 1 |
| Filippi, S | 1 |
| Palitti, F | 2 |
| Martínez-López, W | 1 |
| Fiore, M | 1 |
| Natarajan, AT | 8 |
| Dregalla, RC | 1 |
| Zhou, J | 1 |
| Idate, RR | 1 |
| Battaglia, CL | 1 |
| Liber, HL | 1 |
| Bailey, SM | 1 |
| Zhang, H | 1 |
| Zhao, W | 1 |
| Wang, Y | 1 |
| Li, N | 1 |
| Wu, Z | 1 |
| Liu, Y | 1 |
| Chen, J | 1 |
| Cai, Y | 1 |
| Hori, T | 1 |
| van Zeeland, AA | 4 |
| Zwanenburg, TS | 5 |
| Hansson, K | 2 |
| Kihlman, BA | 2 |
| Tanzarella, C | 1 |
| Mullenders, LH | 1 |
| Schwartz, JL | 2 |
| Weichselbaum, RR | 2 |
| Padovani, L | 1 |
| Appolloni, M | 1 |
| Anzidei, P | 1 |
| Tedeschi, B | 1 |
| Caporossi, D | 1 |
| Vernole, P | 1 |
| Mauro, F | 1 |
| Di Leonardo, A | 1 |
| Cavolina, P | 1 |
| Maddalena, A | 1 |
| Zhang, A | 1 |
| Lin, MS | 1 |
| Fujimoto, A | 1 |
| Helbig, R | 1 |
| Gerland, E | 1 |
| Speit, G | 2 |
| Matsuda, Y | 5 |
| Tobari, I | 5 |
| Domínguez, I | 1 |
| Mateos, S | 1 |
| Cortés, F | 1 |
| D'Souza, D | 1 |
| Thomas, IM | 1 |
| Das, BC | 1 |
| Deng, CZ | 1 |
| AbuBakar, S | 1 |
| Fons, MP | 1 |
| Boldogh, I | 1 |
| Albrecht, T | 1 |
| Köberle, B | 1 |
| Burkart, W | 1 |
| MacLaren, RA | 1 |
| Au, WW | 1 |
| Legator, MS | 1 |
| Seki, N | 2 |
| Utsugi-Takeuchi, T | 1 |
| Maemori, M | 2 |
| De Kok, AJ | 1 |
| Sips, H | 1 |
| Den Engelse, L | 1 |
| Simons, JW | 1 |
| Sjouke, T | 1 |
| Zwanenburg, B | 1 |
| van Buul, PP | 1 |
| Mullenders, LF | 1 |
| Wiencke, JK | 3 |
| Morgan, WF | 4 |
| Afzal, V | 2 |
| Olivieri, G | 1 |
| Wolff, S | 2 |
| Bodycote, J | 1 |
| Doida, Y | 1 |
| Fero, ML | 1 |
| Hahn, P | 1 |
| Kapp, LN | 1 |
| Pantelias, GE | 1 |
| Politis, G | 1 |
| Sabani, CD | 1 |
| Andersson, HC | 1 |
| Jan, KY | 1 |
| Huang, RY | 1 |
| Lee, TC | 1 |
| Darroudi, F | 3 |
| Oleinick, NL | 1 |
| Evans, HH | 1 |
| Brown-Lindquist, P | 1 |
| Csukás, I | 1 |
1 review available for 3-aminobenzamide and Abnormalities, Autosome
| Article | Year |
|---|---|
Poly(ADP-ribose) and the response of cells to ionizing radiation.
Topics: Animals; Benzamides; Cell Cycle; Cell Survival; Cell Transformation, Neoplastic; Chromosome Aberrati | 1985 |
38 other studies available for 3-aminobenzamide and Abnormalities, Autosome
| Article | Year |
|---|---|
Influence of 3-aminobenzamide, an inhibitor of poly(ADP-ribose)polymerase, in the evaluation of the genotoxicity of doxorubicin, cyclophosphamide and zidovudine in female mice.
Topics: Animals; Benzamides; Chromosome Aberrations; Comet Assay; Cyclophosphamide; DNA Damage; Doxorubicin; | 2014 |
Relationship between DNA repair and formation of sister chromatid exchanges and chromatid aberrations under the influence of poly(ADP-ribose) polymerase inhibition by 3-aminobenzamide.
Topics: Animals; Benzamides; Bromodeoxyuridine; Cell Line; Chromatids; Chromosome Aberrations; DNA Repair; H | 2010 |
Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs.
Topics: Adenosine Diphosphate; Antigens, Nuclear; Benzamides; Biocatalysis; Cell Death; Cell Line, Transform | 2010 |
Induction of cytogenetic adaptive response in spermatogonia and spermatocytes by pre-exposure of mouse testis to low-dose (12)C(6+) ions.
Topics: Animals; Benzamides; Carbon; Chromosome Aberrations; Chromosomes, Mammalian; Dose-Response Relations | 2008 |
High incidence of sister chromatid exchanges and chromatid interchanges in the conditions of lowered activity of poly(ADP-ribose)polymerase.
Topics: Animals; Benzamides; Cell Line; Chromatids; Chromosome Aberrations; Cricetinae; Cricetulus; Crossing | 1981 |
Influence of inhibitors of poly(ADP-ribose) polymerase on DNA repair, chromosomal alterations, and mutations.
Topics: Animals; Benzamides; Cell Line; Cells, Cultured; Chromosome Aberrations; Cricetinae; DNA Repair; Fem | 1983 |
Influence of caffeine and 3-aminobenzamide in G2 on the frequency of chromosomal aberrations induced by thiotepa, mitomycin C and N-methyl-N-nitro-N'-nitrosoguanidine in human lymphocytes.
Topics: Benzamides; Caffeine; Cell Cycle; Cells, Cultured; Chromosome Aberrations; DNA Repair; Drug Synergis | 1984 |
DNA lesions, chromosomal aberrations and G2 delay in CHO cells cultured in medium containing bromo- or chloro-deoxyuridine.
Topics: Animals; Benzamides; Bromodeoxyuridine; Caffeine; Cell Survival; Chromosome Aberrations; Cricetinae; | 1984 |
The mechanism of 3-aminobenzamide-mediated increases in spontaneous and induced SCEs.
Topics: Alkylating Agents; Animals; Antipain; Benzamides; Bromodeoxyuridine; Cell Line; Chromosome Aberratio | 1984 |
Do human lymphocytes exposed to the fallout of the Chernobyl accident exhibit an adaptive response? 1. Challenge with ionizing radiation.
Topics: Adaptation, Physiological; Benzamides; Cell Cycle; Cells, Cultured; Child; Chromosome Aberrations; F | 1995 |
DNA topoisomerase II inhibition and gene amplification in V79/B7 cells.
Topics: Animals; Aspartate Carbamoyltransferase; Aspartic Acid; Benzamides; Carbamoyl-Phosphate Synthase (Gl | 1993 |
Effects of 5-hydroxymethyl-2'-deoxyuridine and 3-aminobenzamide on chromosome aberrations in cultured human lymphocytes.
Topics: Antineoplastic Agents; Benzamides; Chromosome Aberrations; DNA Repair; Drug Synergism; Humans; Lymph | 1993 |
The molecular nature of mutations induced by adriamycin at the hprt locus of V79 cells.
Topics: Animals; Benzamides; Cell Line; Chromatids; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Repa | 1994 |
Radiosensitivity and effects of repair inhibitors for X-ray-induced chromosomal damage in mouse zygotes in S and G2 phases.
Topics: Animals; Benzamides; Caffeine; Chromosome Aberrations; Cytarabine; DNA Repair; Female; G2 Phase; Mal | 1995 |
Yield of SCEs and translocations produced by 3 aminobenzamide in cultured Chinese hamster cells.
Topics: Animals; Benzamides; Bromodeoxyuridine; CHO Cells; Chromosome Aberrations; Cricetinae; Dose-Response | 2000 |
Effect of inhibitor of poly (ADP-ribose) polymerase in blood lymphocyte cultures of untreated leprosy patients.
Topics: Benzamides; Cells, Cultured; Chromosome Aberrations; DNA Repair; Humans; Leprosy; Lymphocytes; Male; | 1992 |
Modulation of the frequency of human cytomegalovirus-induced chromosome aberrations by camptothecin.
Topics: Benzamides; Camptothecin; Cells, Cultured; Chromosome Aberrations; Cytomegalovirus Infections; DNA R | 1992 |
Molecular characterization of mutations at the hprt locus in V79 Chinese hamster cells induced by bleomycin in the presence of inhibitors of DNA repair.
Topics: Animals; Benzamides; Bleomycin; Blotting, Southern; Cell Line; Chromosome Aberrations; Cricetinae; C | 1991 |
Effect of 3-aminobenzamide on chromosome damage in human blood lymphocytes adapted to bleomycin.
Topics: Adaptation, Biological; Adult; Benzamides; Bleomycin; Chromosome Aberrations; DNA Repair; Female; Hu | 1989 |
The effect of 3-aminobenzamide on X-ray induction of chromosome aberrations in Down syndrome lymphocytes.
Topics: Benzamides; Chromosome Aberrations; Chromosomes, Human; Down Syndrome; Humans; In Vitro Techniques; | 1989 |
Changes in X-ray sensitivity of mouse eggs from fertilization to the early pronuclear stage, and their repair capacity.
Topics: Animals; Benzamides; Caffeine; Chromosome Aberrations; DNA Repair; Female; Male; Mice; Oocytes; Ovum | 1989 |
Relationship between cell cycle stage in the fertilized egg of mice and repair capacity for X-ray-induced damage in the sperm.
Topics: Animals; Benzamides; Caffeine; Cell Cycle; Chromosome Aberrations; Cytarabine; DNA Damage; DNA Repai | 1989 |
Prolonged in vitro exposure of Syrian hamster embryo cells to 3-aminobenzamide induces transformation and chromosomal alterations but not gene mutations.
Topics: Animals; Benzamides; Cell Transformation, Neoplastic; Cells, Cultured; Chromosome Aberrations; Crice | 1989 |
Mechanism of chromosome aberration induction in the mouse egg fertilized with sperm recovered from postmeiotic germ cells treated with methyl methanesulfonate.
Topics: Animals; Benzamides; Caffeine; Chromosome Aberrations; Cytarabine; Female; Hydroxyurea; Male; Meiosi | 1989 |
Repair capacity of fertilized mouse eggs for X-ray damage induced in sperm and mature oocytes.
Topics: Animals; Benzamides; Caffeine; Chromosome Aberrations; Chromosome Banding; Cleavage Stage, Ovum; Cyt | 1989 |
Inhibition of ADP-ribosylation increases X-ray-induced chromosomal damage in mouse testis and bone-marrow cells in vivo.
Topics: Animals; Benzamides; Bone Marrow; Chromosome Aberrations; Chromosomes; Male; Mice; Poly(ADP-ribose) | 1986 |
Modulation of mutagen-induced biological effects by inhibitors of DNA repair.
Topics: Alkylating Agents; Benzamides; Chromosome Aberrations; Cytarabine; DNA; DNA Polymerase II; DNA Repai | 1986 |
Cell cycle-dependent potentiation of X-ray-induced chromosomal aberrations by 3-aminobenzamide.
Topics: Benzamides; Cell Cycle; Cells, Cultured; Chromosome Aberrations; Chromosomes, Human; Humans; Lymphoc | 1987 |
Evidence that the [3H]thymidine-induced adaptive response of human lymphocytes to subsequent doses of X-rays involves the induction of a chromosomal repair mechanism.
Topics: Adaptation, Biological; Adult; Benzamides; Chromosome Aberrations; DNA; DNA Repair; Female; Humans; | 1986 |
Spontaneous and 3-aminobenzamide-induced sister-chromatid exchange frequencies estimated by ring chromosome analysis.
Topics: Animals; Azure Stains; Benzamides; Bromodeoxyuridine; Cell Cycle; Cell Line; Chromosome Aberrations; | 1986 |
3-Aminobenzamide does not affect X-ray-induced cytogenetic damage in G0 human lymphocytes.
Topics: Animals; Benzamides; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; Dose-Response Relati | 1986 |
Effects of inhibitors of DNA repair on the frequencies of chromosomal aberrations induced by X-rays or alkylating agents in cultured human lymphocytes.
Topics: Alkylating Agents; Benzamides; Caffeine; Cells, Cultured; Chromatids; Chromosome Aberrations; DNA Re | 1986 |
Different modes of action of sodium arsenite, 3-aminobenzamide, and caffeine on the enhancement of ethyl methanesulfonate clastogenicity.
Topics: Animals; Arsenic; Arsenites; Benzamides; Caffeine; Cell Cycle; Cell Line; Cell Transformation, Neopl | 1986 |
Cytological characterization of Chinese hamster ovary X-ray-sensitive mutant cells xrs 5 and xrs 6. I. Induction of chromosomal aberrations by X-irradiation and its modulation with 3-aminobenzamide and caffeine.
Topics: Animals; Benzamides; Caffeine; Cell Cycle; Cell Line; Cell Survival; Chromosome Aberrations; Criceti | 1987 |
Effects of 3-aminobenzamide on Chinese hamster cells treated with thymidine analogues and DNA-damaging agents. Chromosomal aberrations, mutations and cell-cycle progression.
Topics: Alkylating Agents; Animals; Benzamides; Cell Cycle; Cell Line; Chromosome Aberrations; Cricetinae; C | 1985 |
Comutagenic effects of 3-aminobenzamide in Chinese hamster ovary cells.
Topics: Animals; Benzamides; Cell Survival; Cells, Cultured; Chromosome Aberrations; Cricetinae; Cricetulus; | 1985 |
Cytological characterization of repair-deficient CHO cell line 43-3B. I. Induction of chromosomal aberrations and sister-chromatid exchanges by UV and its modulation with 3-aminobenzamide.
Topics: Animals; Benzamides; Cell Cycle; Cell Line; Chromosome Aberrations; Cricetinae; Cricetulus; DNA Repa | 1985 |
3-Aminobenzamide sensitizes cultured Chinese hamster cells with bromodeoxyuridine-substituted DNA to genetic damage induced by long-wave UV.
Topics: Animals; Benzamides; Bromodeoxyuridine; Cell Line; Cell Survival; Chromosome Aberrations; Cricetinae | 1985 |