Compounds > 3-amino-1-4-dimethyl-5h-pyrido(4-3-b)indole

3-amino-1-4-dimethyl-5h-pyrido(4-3-b)indole and Intestinal-Neoplasms

3-amino-1-4-dimethyl-5h-pyrido(4-3-b)indole has been researched along with Intestinal-Neoplasms* in 1 studies

Other Studies

1 other study(ies) available for 3-amino-1-4-dimethyl-5h-pyrido(4-3-b)indole and Intestinal-Neoplasms

Article	Year
Carcinogenicity in rats of a mutagenic compound, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole, from tryptophan pyrolysate. Japanese journal of cancer research : Gann, 1985, Volume: 76, Issue:9 3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) is a mutagenic principle isolated from a tryptophan pyrolysate. When Trp-P-1 was given to male and female F344 rats at concentrations of 0.015% and 0.02%, respectively, in the diet, it induced hepatocellular carcinomas in high incidence within a year. No tumor was found in control rats. Topics: Animals; Carbolines; Carcinogens; Female; Intestinal Neoplasms; Liver Neoplasms, Experimental; Male; Mutagens; Rats; Rats, Inbred F344; Sex Characteristics; Time Factors	1985

Article

Year

Carcinogenicity in rats of a mutagenic compound, 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole, from tryptophan pyrolysate.

Japanese journal of cancer research : Gann, 1985, Volume: 76, Issue:9

3-Amino-1,4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) is a mutagenic principle isolated from a tryptophan pyrolysate. When Trp-P-1 was given to male and female F344 rats at concentrations of 0.015% and 0.02%, respectively, in the diet, it induced hepatocellular carcinomas in high incidence within a year. No tumor was found in control rats.

Topics: Animals; Carbolines; Carcinogens; Female; Intestinal Neoplasms; Liver Neoplasms, Experimental; Male; Mutagens; Rats; Rats, Inbred F344; Sex Characteristics; Time Factors

1985