3-8-dihydroxy-6h-dibenzo(b-d)pyran-6-one has been researched along with Hand--Foot-and-Mouth-Disease* in 1 studies
1 other study(ies) available for 3-8-dihydroxy-6h-dibenzo(b-d)pyran-6-one and Hand--Foot-and-Mouth-Disease
| Article | Year |
|---|---|
Urolithin A inhibits enterovirus 71 replication and promotes autophagy and apoptosis of infected cells in vitro.
Hand, foot, and mouth disease (HFMD) is a serious threat to the health of infants, and it can be caused by enterovirus 71 (EV71). The clinical symptoms are mostly self-limiting, but some infections develop into aseptic meningitis with poor prognosis and even death. In this study, urolithin A (UroA), an intestinal metabolite of ellagic acid, significantly inhibited the replication of EV71 in cells. Further evaluation showed that UroA was better than ribavirin in terms of its 50% cytopathic concentration (CC Topics: Apoptosis; Autophagy; Coumarins; Enterovirus; Enterovirus A, Human; Enterovirus Infections; Hand, Foot and Mouth Disease; Humans; Infant | 2022 |