Compounds > 3,7-dimethyl-1-propargylxanthine
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3,7-dimethyl-1-propargylxanthine and Innate Inflammatory Response

3,7-dimethyl-1-propargylxanthine has been researched along with Innate Inflammatory Response in 8 studies

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (62.50)18.2507
2000's2 (25.00)29.6817
2010's1 (12.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Edwards, BS; Graves, SW; Saunders, MJ; Sklar, LA; Zhu, J1
Chaimovitz, C; Douvdevani, A; Mazar, J; Nakav, S; Rogachev, B; Ziv, NY; Zlotnik, M1
Alvarez, C; Ferreira, A; Gatica, H; Goecke, IA; Henríquez, J; Molina, ML; Salas, K1
Cronstein, BN; Naime, D; Ostad, E2
Bong, GW; Firestein, GS; Rosengren, S1
Cronstein, BN; Montesinos, MC; Weissmann, G2

Other Studies

8 other study(ies) available for 3,7-dimethyl-1-propargylxanthine and Innate Inflammatory Response

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Proteins; High-Throughput Screening Assays; Humans; Inflammation; Kinetics; Microspheres; Peptide Hydrolases; Peptides; Reproducibility of Results; Temperature

2010
Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation.
    Kidney international, 2006, Volume: 70, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Antihypertensive Agents; Cells, Cultured; Disease Models, Animal; Down-Regulation; Epithelium; Escherichia coli; Female; Humans; Inflammation; Interleukin-6; Leukocytes; Mice; Mice, Inbred Strains; Peritonitis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Purinergic P1; RNA, Messenger; Theobromine; Tumor Necrosis Factor-alpha; Up-Regulation; Xanthines

2006
Methotrexate regulates the expression of glucocorticoid receptor alpha and beta isoforms in normal human peripheral mononuclear cells and human lymphocyte cell lines in vitro.
    Molecular immunology, 2007, Volume: 44, Issue:8

    Topics: Adenosine; Adenosine A2 Receptor Antagonists; Asthma; Autoimmune Diseases; Drug Synergism; Gene Expression Regulation; Humans; Immunosuppressive Agents; Inflammation; Jurkat Cells; Lipopolysaccharides; Lymphocytes; Methotrexate; Protein Isoforms; Receptors, Glucocorticoid; Theobromine; Vasodilator Agents

2007
The antiinflammatory effects of methotrexate are mediated by adenosine.
    Advances in experimental medicine and biology, 1994, Volume: 370

    Topics: Acyltransferases; Adenosine; Adenosine Deaminase; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Hydroxymethyl and Formyl Transferases; Inflammation; Kinetics; Leukocytes; Methotrexate; Mice; Phosphoribosylaminoimidazolecarboxamide Formyltransferase; Purinergic P1 Receptor Antagonists; Ribonucleotides; Theobromine; Xanthines

1994
The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:6

    Topics: Adenosine; Adenosine Deaminase; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Female; Inflammation; Kinetics; Leukocytes; Methotrexate; Mice; Mice, Inbred BALB C; Purinergic P1 Receptor Antagonists; Ribonucleotides; Spleen; Theobromine; Time Factors

1993
Spinal cord adenosine receptor stimulation in rats inhibits peripheral neutrophil accumulation. The role of N-methyl-D-aspartate receptors.
    The Journal of clinical investigation, 1996, Dec-15, Volume: 98, Issue:12

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Anti-Inflammatory Agents; Carrageenan; Catheterization; Central Nervous System; Dexamethasone; Excitatory Amino Acid Antagonists; Inflammation; N-Methylaspartate; Neutrophils; Peroxidase; Phenethylamines; Propionates; Purinergic P1 Receptor Antagonists; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Signal Transduction; Skin; Spinal Cord; Theobromine

1996
Salicylates and sulfasalazine, but not glucocorticoids, inhibit leukocyte accumulation by an adenosine-dependent mechanism that is independent of inhibition of prostaglandin synthesis and p105 of NFkappaB.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, May-25, Volume: 96, Issue:11

    Topics: Adenosine Deaminase; Animals; Aspirin; Carrageenan; Cyclooxygenase 1; Cyclooxygenase 2; Female; Glucocorticoids; Inflammation; Isoenzymes; Leukocytes; Male; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Knockout; NF-kappa B; NF-kappa B p50 Subunit; Prostaglandin-Endoperoxide Synthases; Protein Precursors; Purinergic P1 Receptor Antagonists; Salicylates; Sodium Salicylate; Sulfasalazine; Theobromine

1999
Sites of action for future therapy: an adenosine-dependent mechanism by which aspirin retains its antiinflammatory activity in cyclooxygenase-2 and NFkappaB knockout mice.
    Osteoarthritis and cartilage, 1999, Volume: 7, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Inflammation; Mice; Mice, Knockout; Theobromine

1999