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3,7-dimethyl-1-propargylxanthine and Disease Models, Animal

3,7-dimethyl-1-propargylxanthine has been researched along with Disease Models, Animal in 13 studies

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's4 (30.77)18.2507
2000's5 (38.46)29.6817
2010's3 (23.08)24.3611
2020's1 (7.69)2.80

Authors

AuthorsStudies
Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ1
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Altavilla, D; Antonuccio, P; Arena, S; Bitto, A; Galfo, F; Irrera, N; Magno, C; Marini, H; Micali, A; Minutoli, L; Pizzino, G; Rinaldi, M; Romeo, C; Squadrito, F1
Gong, ZH; Huang, B; Jia, YX; Su, RB; Wang, ML; Wang, ZT; Yi, SP; Yu, G; Zhang, FY1
Chaimovitz, C; Douvdevani, A; Mazar, J; Nakav, S; Rogachev, B; Ziv, NY; Zlotnik, M1
Fan, YJ; Lautt, WW; Ming, Z; Yang, X1
Chiang, CP; Chiang, PH; Huang, CH; Shen, MR; Tsai, EM; Wu, CC; Wu, SN1
Klitgaard, H; Knutsen, LJ; Thomsen, C1
Cronstein, BN; Naime, D; Ostad, E1
Pèzzola, A; Popoli, P; Reggio, R1
Beilstein, M; Castagnoli, K; Castagnoli, N; Chen, JF; Petzer, JP; Schwarzschild, MA; Sonsalla, PK; Staal, R; Xu, K; Xu, YH1
Hamann, M; Richter, A1
Iwamoto, T; Miki, S; Noguchi, K; Okamoto, K; Sato, S; Senba, E; Yasuda, T; Yoshinaga, N1

Trials

1 trial(s) available for 3,7-dimethyl-1-propargylxanthine and Disease Models, Animal

ArticleYear
Adenosine modulation of neurotransmission in penile erection.
    British journal of clinical pharmacology, 1994, Volume: 38, Issue:4

    Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Adult; Aged; Alprostadil; Animals; Antihypertensive Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; Male; Middle Aged; Muscle Contraction; Muscle, Smooth; Nitric Oxide; Norepinephrine; Penile Erection; Penis; Phenethylamines; Phenylisopropyladenosine; Purinergic P1 Receptor Agonists; Rabbits; Synaptic Transmission; Theobromine; Vasodilator Agents

1994

Other Studies

12 other study(ies) available for 3,7-dimethyl-1-propargylxanthine and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Role of Inhibitors of Apoptosis Proteins in Testicular Function and Male Fertility: Effects of Polydeoxyribonucleotide Administration in Experimental Varicocele.
    BioMed research international, 2015, Volume: 2015

    Topics: Adenosine A2 Receptor Antagonists; Animals; Disease Models, Animal; Fertility; Gene Expression Regulation; Male; Microtubule-Associated Proteins; Neuronal Apoptosis-Inhibitory Protein; Oligodeoxyribonucleotides; Rats; Receptors, Adenosine A2; Spermatogenesis; Survivin; Testis; Theobromine; Varicocele

2015
Antinociceptive effects of incarvillateine, a monoterpene alkaloid from Incarvillea sinensis, and possible involvement of the adenosine system.
    Scientific reports, 2015, Nov-03, Volume: 5

    Topics: Adenosine; Alkaloids; Analgesics; Animals; Antineoplastic Agents, Phytogenic; Bignoniaceae; Disease Models, Animal; Edema; Freund's Adjuvant; Hyperalgesia; Interleukin-1beta; Medicine, Chinese Traditional; Mice; Monoterpenes; Motor Activity; Paclitaxel; Pain Measurement; Theobromine; Theophylline; Xanthines

2015
Adenosine is upregulated during peritonitis and is involved in downregulation of inflammation.
    Kidney international, 2006, Volume: 70, Issue:4

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A2 Receptor Agonists; Adenosine A2 Receptor Antagonists; Animals; Antihypertensive Agents; Cells, Cultured; Disease Models, Animal; Down-Regulation; Epithelium; Escherichia coli; Female; Humans; Inflammation; Interleukin-6; Leukocytes; Mice; Mice, Inbred Strains; Peritonitis; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Receptor, Adenosine A1; Receptor, Adenosine A2A; Receptors, Purinergic P1; RNA, Messenger; Theobromine; Tumor Necrosis Factor-alpha; Up-Regulation; Xanthines

2006
Contribution of hepatic adenosine A1 receptors to renal dysfunction associated with acute liver injury in rats.
    Hepatology (Baltimore, Md.), 2006, Volume: 44, Issue:4

    Topics: Adenosine A1 Receptor Antagonists; Adenosine A2 Receptor Antagonists; Animals; Chemical and Drug Induced Liver Injury; Denervation; Disease Models, Animal; Liver; Liver Diseases; Male; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptors, Adenosine A2; Renal Insufficiency; Sodium; Theobromine; Theophylline; Thioacetamide; Urine; Xanthines

2006
Contrasting effects of adenosine A1 and A2 receptor ligands in different chemoconvulsive rodent models.
    European journal of pharmacology, 1993, Oct-05, Volume: 242, Issue:3

    Topics: Animals; Anticonvulsants; Convulsants; Disease Models, Animal; Glutamates; Glutamic Acid; Male; Mice; Mice, Inbred Strains; Purinergic P1 Receptor Antagonists; Receptors, GABA-A; Receptors, Purinergic P1; Seizures; Theobromine; Xanthines

1993
The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:6

    Topics: Adenosine; Adenosine Deaminase; Aminoimidazole Carboxamide; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Disease Models, Animal; Female; Inflammation; Kinetics; Leukocytes; Methotrexate; Mice; Mice, Inbred BALB C; Purinergic P1 Receptor Antagonists; Ribonucleotides; Spleen; Theobromine; Time Factors

1993
The intrastratial injection of an adenosine A(2) receptor antagonist prevents frontal cortex EEG abnormalities in a rat model of Huntington's disease.
    Brain research, 1999, Jun-12, Volume: 831, Issue:1-2

    Topics: Animals; Corpus Striatum; Disease Models, Animal; Electroencephalography; Frontal Lobe; Huntington Disease; Male; Microinjections; Neuroprotective Agents; Purinergic P1 Receptor Antagonists; Quinolinic Acid; Rats; Rats, Wistar; Theobromine

1999
Neuroprotection by caffeine and A(2A) adenosine receptor inactivation in a model of Parkinson's disease.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2001, May-15, Volume: 21, Issue:10

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Caffeine; Catechols; Corpus Striatum; Disease Models, Animal; Dopamine; Dose-Response Relationship, Drug; Immunity, Innate; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neuroprotective Agents; Parkinsonian Disorders; Purinergic P1 Receptor Antagonists; Purines; Pyrimidines; Receptor, Adenosine A2A; Receptors, Purinergic P1; Theobromine; Triazoles; Xanthines

2001
Effects of adenosine receptor agonists and antagonists in a genetic animal model of primary paroxysmal dystonia.
    British journal of pharmacology, 2001, Volume: 134, Issue:2

    Topics: Adenosine; Animals; Caffeine; Cricetinae; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Female; Male; Mesocricetus; Muscle Contraction; Mutation; Phenethylamines; Purinergic P1 Receptor Agonists; Purinergic P1 Receptor Antagonists; Quinazolines; Theobromine; Theophylline; Triazines; Triazoles; Xanthines

2001
A novel analgesic compound OT-7100 attenuates nociceptive responses in animal models of inflammatory and neuropathic hyperalgesia: a possible involvement of adenosinergic anti-nociception.
    Japanese journal of pharmacology, 2001, Volume: 87, Issue:3

    Topics: Adenosine; Analgesics, Non-Narcotic; Animals; Disease Models, Animal; Guinea Pigs; Hyperalgesia; Immunohistochemistry; In Vitro Techniques; Male; Proto-Oncogene Proteins c-fos; Pyrazoles; Pyrimidines; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Theobromine; Xanthines

2001