Compounds > 3-5-diethoxy-4-aminomethylpyridine

3-5-diethoxy-4-aminomethylpyridine and Cardiomyopathies

3-5-diethoxy-4-aminomethylpyridine has been researched along with Cardiomyopathies* in 1 studies

Other Studies

1 other study(ies) available for 3-5-diethoxy-4-aminomethylpyridine and Cardiomyopathies

Article	Year
Semicarbazide-sensitive amine oxidase activity in the human heart. Molecular genetics and metabolism, 1998, Volume: 64, Issue:1 A semicarbazide-sensitive amine oxidase with affinity for benzylamine (Bz.SSAO) was found in the human heart. This enzymatic activity has a K(m) of 278 +/- 35.3 microM and a V(m) of 114.7 +/- 14.7 nmol mg-1 min-1 (mean +/- SE of eight hearts) for benzylamine and is strongly inhibited by 1 mM histamine and by B24, a specific inhibitor of Bz.SSAO. No diamine oxidase activity was found in the human heart. The levels of MAo and B were assayed: MAO A showed a K(m) of 137.1 +/- 16.2 microM and a V(m) of 10.4 +/- 2.5 nmol mg-1 min-1 for serotonin; MAo B had a K(m) of 9.9 +/- 1.6 microM and V(m) of 4.3 +/- 1.1 nmol mg-1 min-1 for beta-phenylethylamine (mean +/- SE of seven hearts). The human heart has high MAO B activity and Bz.SSAO with histaminase activity. Topics: Adult; Aging; Amine Oxidase (Copper-Containing); Amines; Benzylamine Oxidase; Benzylamines; Binding, Competitive; Cardiomyopathies; Enzyme Inhibitors; Female; Histamine; Humans; Kinetics; Male; Middle Aged; Monoamine Oxidase; Myocardium; Putrescine; Pyridines; Semicarbazides	1998

Article

Year

Semicarbazide-sensitive amine oxidase activity in the human heart.

Molecular genetics and metabolism, 1998, Volume: 64, Issue:1

A semicarbazide-sensitive amine oxidase with affinity for benzylamine (Bz.SSAO) was found in the human heart. This enzymatic activity has a K(m) of 278 +/- 35.3 microM and a V(m) of 114.7 +/- 14.7 nmol mg-1 min-1 (mean +/- SE of eight hearts) for benzylamine and is strongly inhibited by 1 mM histamine and by B24, a specific inhibitor of Bz.SSAO. No diamine oxidase activity was found in the human heart. The levels of MAo and B were assayed: MAO A showed a K(m) of 137.1 +/- 16.2 microM and a V(m) of 10.4 +/- 2.5 nmol mg-1 min-1 for serotonin; MAo B had a K(m) of 9.9 +/- 1.6 microM and V(m) of 4.3 +/- 1.1 nmol mg-1 min-1 for beta-phenylethylamine (mean +/- SE of seven hearts). The human heart has high MAO B activity and Bz.SSAO with histaminase activity.

Topics: Adult; Aging; Amine Oxidase (Copper-Containing); Amines; Benzylamine Oxidase; Benzylamines; Binding, Competitive; Cardiomyopathies; Enzyme Inhibitors; Female; Histamine; Humans; Kinetics; Male; Middle Aged; Monoamine Oxidase; Myocardium; Putrescine; Pyridines; Semicarbazides

1998