3-5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide and Body-Weight

3-5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide has been researched along with Body-Weight* in 1 studies

Other Studies

1 other study(ies) available for 3-5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide and Body-Weight

Article	Year
2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors. Bioorganic & medicinal chemistry letters, 2007, Jun-01, Volume: 17, Issue:11 A novel series of 2-hydroxy-N-arylbenzenesulfonamides were identified to be ATP-citrate lyase (ACL) inhibitors with compound 9 displaying potent in vitro activity (IC(50)=0.13 microM). Chronic oral dosing of compound 9 in high-fat fed mice lowered plasma cholesterol, triglyceride, and glucose, as well as inhibited weight gain. Topics: Adipose Tissue; Animals; Anti-Obesity Agents; ATP Citrate (pro-S)-Lyase; Benzene; Blood Glucose; Body Weight; Cells, Cultured; Cholesterol; Enzyme Inhibitors; Mice; Rats; Structure-Activity Relationship; Sulfonamides; Triglycerides	2007

Article

Year

2-hydroxy-N-arylbenzenesulfonamides as ATP-citrate lyase inhibitors.

Bioorganic & medicinal chemistry letters, 2007, Jun-01, Volume: 17, Issue:11

A novel series of 2-hydroxy-N-arylbenzenesulfonamides were identified to be ATP-citrate lyase (ACL) inhibitors with compound 9 displaying potent in vitro activity (IC(50)=0.13 microM). Chronic oral dosing of compound 9 in high-fat fed mice lowered plasma cholesterol, triglyceride, and glucose, as well as inhibited weight gain.

Topics: Adipose Tissue; Animals; Anti-Obesity Agents; ATP Citrate (pro-S)-Lyase; Benzene; Blood Glucose; Body Weight; Cells, Cultured; Cholesterol; Enzyme Inhibitors; Mice; Rats; Structure-Activity Relationship; Sulfonamides; Triglycerides

2007