Compounds > 3-5-bis(2-fluorobenzylidene)piperidin-4-one

3-5-bis(2-fluorobenzylidene)piperidin-4-one and Leukemia

3-5-bis(2-fluorobenzylidene)piperidin-4-one has been researched along with Leukemia* in 1 studies

Other Studies

1 other study(ies) available for 3-5-bis(2-fluorobenzylidene)piperidin-4-one and Leukemia

ArticleYear
Apoptosis Induced by the Curcumin Analogue EF-24 Is Neither Mediated by Oxidative Stress-Related Mechanisms nor Affected by Expression of Main Drug Transporters ABCB1 and ABCG2 in Human Leukemia Cells.
    International journal of molecular sciences, 2017, Oct-31, Volume: 18, Issue:11

    The synthetic curcumin analogue, 3,5-bis[(2-fluorophenyl)methylene]-4-piperidinone (EF-24), suppresses NF-κB activity and exhibits antiproliferative effects against a variety of cancer cells in vitro. Recently, it was reported that EF-24-induced apoptosis was mediated by a redox-dependent mechanism. Here, we studied the effects of

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily G, Member 2; Benzylidene Compounds; Cell Line, Tumor; Glutathione; Humans; Leukemia; Neoplasm Proteins; Oxidative Stress; Piperidones; Reactive Oxygen Species

2017