3,4-methylenedioxyamphetamine has been researched along with Neuroleptic Malignant Syndrome in 2 studies
3,4-Methylenedioxyamphetamine: An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally.
Neuroleptic Malignant Syndrome: A potentially fatal syndrome associated primarily with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS) which are in turn associated with dopaminergic receptor blockade (see RECEPTORS, DOPAMINE) in the BASAL GANGLIA and HYPOTHALAMUS, and sympathetic dysregulation. Clinical features include diffuse MUSCLE RIGIDITY; TREMOR; high FEVER; diaphoresis; labile blood pressure; cognitive dysfunction; and autonomic disturbances. Serum CPK level elevation and a leukocytosis may also be present. (From Adams et al., Principles of Neurology, 6th ed, p1199; Psychiatr Serv 1998 Sep;49(9):1163-72)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nimmo, SM | 1 |
| Kennedy, BW | 1 |
| Tullett, WM | 1 |
| Blyth, AS | 1 |
| Dougall, JR | 1 |
| Ames, D | 1 |
| Wirshing, WC | 1 |
2 other studies available for 3,4-methylenedioxyamphetamine and Neuroleptic Malignant Syndrome
| Article | Year |
|---|---|
Drug-induced hyperthermia.
Topics: 3,4-Methylenedioxyamphetamine; Adult; Designer Drugs; Female; Fluoxetine; Humans; Male; Middle Aged; | 1993 |
Ecstasy, the serotonin syndrome, and neuroleptic malignant syndrome--a possible link?
Topics: 3,4-Methylenedioxyamphetamine; Central Nervous System; Humans; Neuroleptic Malignant Syndrome; Recep | 1993 |