3,4-methylenedioxyamphetamine has been researched along with Acute Post-Traumatic Stress Disorder in 20 studies
3,4-Methylenedioxyamphetamine: An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Measures of PTSD, depression, self-compassion, and mindfulness were obtained at baseline, after a 12-week loving-kindness meditation course, and 3 months later." | 2.78 | Loving-kindness meditation for posttraumatic stress disorder: a pilot study. ( Felleman, B; Kearney, DJ; Malte, CA; Martinez, ME; McManus, C; Simpson, TL, 2013) |
| "Posttraumatic stress disorder (PTSD) is prevalent among combat veterans and is associated with intimate relationship difficulties." | 1.51 | Longitudinal associations in the direction and prediction of PTSD symptoms and romantic relationship impairment over one year in post 9/11 veterans: A comparison of theories and exploration of potential gender differences. ( Benzer, JK; Creech, SK; DeBeer, BB; Kimbrel, NA; Meyer, EC; Morissette, SB, 2019) |
| "A total of 42 veterans with active PTSD (40% female) participated." | 1.40 | Loving-kindness meditation and the broaden-and-build theory of positive emotions among veterans with posttraumatic stress disorder. ( Felleman, B; Kearney, DJ; Malte, CA; Martinez, ME; McManus, C; Simpson, TL, 2014) |
| "All the tested had trauma in their medical history and all of them met the PTSD diagnostic criteria, 75 examinees participated in the Homeland War and they represent the veteran group, and 50 examinees went through a stressful situation during peacetime and they represent the civilian group." | 1.40 | Will the war for the Croatian Homeland War veterans ever end? ( Matić, A; Rak, B; Rak, D, 2014) |
| "Group differences (PTSD versus no PTSD) were examined on measures of important relationships, and no significant differences were found related to parental bonding or perceptions of love by God." | 1.35 | The role of adult attachment, parental bonding, and spiritual love in the adjustment to military trauma. ( Boardman, A; Ghafoori, B; Hierholzer, R; Howsepian, B, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (10.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 13 (65.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Murnane, KS | 1 |
| Weber, GF | 1 |
| Johnson, BN | 1 |
| Yamamoto, BK | 1 |
| Gudelsky, GA | 1 |
| Cantwell-Bartl, AM | 1 |
| Tibballs, J | 1 |
| Boelen, PA | 1 |
| Spuij, M | 1 |
| Reijntjes, AHA | 1 |
| Maccallum, F | 1 |
| Bryant, RA | 1 |
| Ruhlmann, LM | 1 |
| Nelson Goff, BS | 1 |
| Novak, JR | 1 |
| Fuss, C | 1 |
| Gnagi, T | 1 |
| Schiferl, M | 1 |
| Creech, SK | 1 |
| Benzer, JK | 1 |
| Meyer, EC | 1 |
| DeBeer, BB | 1 |
| Kimbrel, NA | 1 |
| Morissette, SB | 1 |
| Hinton, DE | 1 |
| Ojserkis, RA | 1 |
| Jalal, B | 1 |
| Peou, S | 1 |
| Hofmann, SG | 1 |
| Kearney, DJ | 2 |
| Malte, CA | 2 |
| McManus, C | 2 |
| Martinez, ME | 2 |
| Felleman, B | 2 |
| Simpson, TL | 2 |
| Rak, D | 1 |
| Matić, A | 1 |
| Rak, B | 1 |
| Lee, MY | 1 |
| Zaharlick, A | 1 |
| Akers, D | 1 |
| Beck, JG | 1 |
| Grant, DM | 1 |
| Clapp, JD | 1 |
| Palyo, SA | 1 |
| Ghafoori, B | 1 |
| Hierholzer, R | 1 |
| Howsepian, B | 1 |
| Boardman, A | 1 |
| Boelen, P | 1 |
| Riggs, SA | 1 |
| Paulson, A | 1 |
| Tunnell, E | 1 |
| Sahl, G | 1 |
| Atkison, H | 1 |
| Ross, CA | 1 |
| Grünberg, K | 1 |
| Abrams, KM | 1 |
| Robinson, GE | 1 |
| Crosby, SS | 1 |
| McCranie, EW | 1 |
| Hyer, LA | 1 |
| Boudewyns, PA | 1 |
| Woods, MG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Psychosocial Rehabilitation After Moral Injury and Loss With Adaptive Disclosure[NCT03056157] | 173 participants (Actual) | Interventional | 2018-03-01 | Completed | |||
| A Trial of Loving-Kindness Meditation and Cognitive Processing Therapy for PTSD[NCT01962714] | 184 participants (Actual) | Interventional | 2014-12-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
PTSD diagnostic severity was measured using the 30-item CAPS-5 structured interview (range 0-80; higher scores indicate worse PTSD). Linear mixed effects models (LMM) were used to analyze continuous outcomes, with time and time by treatment interaction included as fixed effects to determine if differences exist between conditions by time. Non-inferiority of LKM to CPT-C was claimed if the lower limit of the 95% confidence interval for difference in change rate from baseline to 6-month follow-up in mean CAPS or depression score was greater than (i.e., did not extend beyond) negative delta (defined as 5 points on the CAPS-5 measure). A 2-sided 95% confidence interval of the difference in change rate from baseline to 6-month follow-up between groups (CPT-C minus LKM) was calculated, with a positive value indicating a greater reduction in scores from baseline for LKM compared to CPT-C. (NCT01962714)
Timeframe: 6 months post-intervention
| Intervention | units on a scale (Mean) |
|---|---|
| Loving-Kindness Meditation | 25.92 |
| Cognitive Processing Therapy - Cognitive Only | 28.02 |
Depression was assessed using the National Institute of Health (NIH) Patient-Reported Outcomes Measurement Information System (PROMIS) depression measure. This scale utilizes item-response theory and is scored using a T-score metric with a mean of 50 and SD=10 in the US general population. Higher scores indicate more severe depression. (NCT01962714)
Timeframe: 6 months post-intervention
| Intervention | units on a scale (Mean) |
|---|---|
| Loving-Kindness Meditation | 58.88 |
| Cognitive Processing Therapy - Cognitive Only | 61.22 |
2 reviews available for 3,4-methylenedioxyamphetamine and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Serotonin 2A receptors are a stress response system: implications for post-traumatic stress disorder.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Brain; Cues; Gene Expression; Gene Expression Regulation; Hu | 2019 |
Stalking. Part I: An overview of the problem.
Topics: Adult; Anxiety Disorders; Canada; Crime; Delusions; Depressive Disorder; Domestic Violence; Female; | 1998 |
2 trials available for 3,4-methylenedioxyamphetamine and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Loving-kindness meditation for posttraumatic stress disorder: a pilot study.
Topics: Adult; Depression; Empathy; Female; Humans; Intention; Love; Male; Meditation; Middle Aged; Mindfuln | 2013 |
Loving-kindness meditation for posttraumatic stress disorder: a pilot study.
Topics: Adult; Depression; Empathy; Female; Humans; Intention; Love; Male; Meditation; Middle Aged; Mindfuln | 2013 |
Loving-kindness meditation for posttraumatic stress disorder: a pilot study.
Topics: Adult; Depression; Empathy; Female; Humans; Intention; Love; Male; Meditation; Middle Aged; Mindfuln | 2013 |
Loving-kindness meditation for posttraumatic stress disorder: a pilot study.
Topics: Adult; Depression; Empathy; Female; Humans; Intention; Love; Male; Meditation; Middle Aged; Mindfuln | 2013 |
Impact of Meditation on Mental Health Outcomes of Female Trauma Survivors of Interpersonal Violence With Co-Occurring Disorders: A Randomized Controlled Trial.
Topics: Adult; Behavior Therapy; Comorbidity; Emotional Adjustment; Empathy; Female; Humans; Love; Meditatio | 2017 |
16 other studies available for 3,4-methylenedioxyamphetamine and Acute Post-Traumatic Stress Disorder
| Article | Year |
|---|---|
Effects of stress and MDMA on hippocampal gene expression.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Gene Expression Regulation; Hippocampus; Neurotoxicity Syndr | 2014 |
Parenting a child at home with hypoplastic left heart syndrome: experiences of commitment, of stress, and of love.
Topics: Adaptation, Psychological; Adolescent; Anxiety; Child; Child, Preschool; Female; Humans; Hypoplastic | 2017 |
Prolonged grief and posttraumatic stress in bereaved children: A latent class analysis.
Topics: Adolescent; Bereavement; Child; Death; Demography; Depression; Female; Grief; Humans; Love; Male; Pa | 2017 |
Prolonged grief and attachment security: A latent class analysis.
Topics: Adult; Anxiety; Bereavement; Death; Depression; Female; Grief; Humans; Latent Class Analysis; Love; | 2018 |
Psychological and relational health profiles of soldiers in committed romantic relationships.
Topics: Adaptation, Psychological; Adult; Afghan Campaign 2001-; Anxiety Disorders; Depressive Disorder, Maj | 2018 |
Longitudinal associations in the direction and prediction of PTSD symptoms and romantic relationship impairment over one year in post 9/11 veterans: A comparison of theories and exploration of potential gender differences.
Topics: Adult; Combat Disorders; Female; Humans; Interpersonal Relations; Love; Male; Prospective Studies; S | 2019 |
Loving-kindness in the treatment of traumatized refugees and minority groups: a typology of mindfulness and the nodal network model of affect and affect regulation.
Topics: Asian People; Buddhism; Cambodia; Emotions; Empathy; Female; Humans; Love; Meditation; Mind-Body The | 2013 |
Loving-kindness meditation and the broaden-and-build theory of positive emotions among veterans with posttraumatic stress disorder.
Topics: Combat Disorders; Emotions; Empathy; Female; Humans; Love; Male; Meditation; Middle Aged; Pilot Proj | 2014 |
Will the war for the Croatian Homeland War veterans ever end?
Topics: Croatia; Female; Hate; Humans; Love; Male; Stress Disorders, Post-Traumatic; Stress, Psychological; | 2014 |
Understanding the interpersonal impact of trauma: contributions of PTSD and depression.
Topics: Adolescent; Adult; Affect; Aged; Cognition; Depressive Disorder; Family; Female; Humans; Interperson | 2009 |
The role of adult attachment, parental bonding, and spiritual love in the adjustment to military trauma.
Topics: Adult; Aged; Aged, 80 and over; Child; Courtship; Data Collection; Data Interpretation, Statistical; | 2008 |
Intolerance of uncertainty and emotional distress following the death of a loved one.
Topics: Adult; Affect; Anxiety; Child; Death; Educational Status; Family; Female; Grief; Humans; Interperson | 2010 |
Attachment, personality, and psychopathology among adult inpatients: self-reported romantic attachment style versus Adult Attachment Interview states of mind.
Topics: Adolescent; Adult; Aged; Cognition; Diagnostic and Statistical Manual of Mental Disorders; Dissociat | 2007 |
Contaminated generativity: Holocaust survivors and their children in Germany.
Topics: Aged; Child; Dissociative Disorders; Germany; Holocaust; Humans; Jews; Love; Memory; Psychoanalytic | 2007 |
A mother's prayer.
Topics: Adoption; Humans; Love; Stress Disorders, Post-Traumatic; Violence | 2000 |
Negative parenting behavior, combat exposure, and PTSD symptom severity. Test of a person-event interaction model.
Topics: Adaptation, Psychological; Adult; Father-Child Relations; Hostility; Humans; Life Change Events; Lov | 1992 |