3,4-methylenedioxyamphetamine has been researched along with Acute Liver Injury, Drug-Induced in 10 studies
3,4-Methylenedioxyamphetamine: An amphetamine derivative that inhibits uptake of catecholamine neurotransmitters. It is a hallucinogen. It is less toxic than its methylated derivative but in sufficient doses may still destroy serotonergic neurons and has been used for that purpose experimentally.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The drug is generally thought to be safe among consumers due to its low-mortality rates." | 2.47 | A mechanistic insight into 3,4-methylenedioxymethamphetamine ("ecstasy")-mediated hepatotoxicity. ( Antolino-Lobo, I; Meulenbelt, J; van den Berg, M; van Duursen, MB, 2011) |
| " These outcomes suggest that MDMA metabolism has hazard implications to liver cells even when metabolites are found in low concentrations, as they contribute additively to the overall toxic effect of MDMA." | 1.40 | Mixtures of 3,4-methylenedioxymethamphetamine (ecstasy) and its major human metabolites act additively to induce significant toxicity to liver cells when combined at low, non-cytotoxic concentrations. ( Carmo, H; Carvalho, F; da Silva, DD; Silva, E, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (70.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roque Bravo, R | 1 |
| Carmo, H | 2 |
| Valente, MJ | 1 |
| Silva, JP | 1 |
| Carvalho, F | 2 |
| Bastos, ML | 1 |
| Dias da Silva, D | 1 |
| da Silva, DD | 1 |
| Silva, E | 1 |
| Antolino-Lobo, I | 1 |
| Meulenbelt, J | 1 |
| van den Berg, M | 1 |
| van Duursen, MB | 1 |
| Oranje, WA | 1 |
| von Pol, P | 1 |
| vd Wurff, A | 1 |
| Zeijen, RN | 1 |
| Stockbrügger, RW | 1 |
| Arends, JW | 1 |
| de Man, RA | 1 |
| Wilson, JH | 1 |
| Tjen, HS | 1 |
| Fidler, H | 1 |
| Dhillon, A | 1 |
| Gertner, D | 1 |
| Burroughs, A | 1 |
| Tillmann, HL | 1 |
| van Pelt, FN | 1 |
| Martz, W | 1 |
| Luecke, T | 1 |
| Welp, H | 1 |
| Dörries, F | 1 |
| Veuskens, A | 1 |
| Fischer, M | 1 |
| Manns, MP | 1 |
| Van Hoenacker, FM | 1 |
| Vandaele, L | 1 |
| Kiekens, M | 1 |
| Gorard, DA | 1 |
| Davies, SE | 1 |
| Clark, ML | 1 |
| Shearman, JD | 1 |
| Chapman, RW | 1 |
| Satsangi, J | 1 |
| Ryley, NG | 1 |
| Weatherhead, S | 1 |
2 reviews available for 3,4-methylenedioxyamphetamine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
A mechanistic insight into 3,4-methylenedioxymethamphetamine ("ecstasy")-mediated hepatotoxicity.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Chemical and Drug Induced Liver Injury; Humans; Illicit Drug | 2011 |
XTC-induced hepatitis.
Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adult; Biopsy; Chemical and Drug Induced Liver Injury; | 1994 |
8 other studies available for 3,4-methylenedioxyamphetamine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
From street to lab: in vitro hepatotoxicity of buphedrone, butylone and 3,4-DMMC.
Topics: 3,4-Methylenedioxyamphetamine; Animals; Autophagy; Butyrophenones; Cell Line, Tumor; Chemical and Dr | 2021 |
Mixtures of 3,4-methylenedioxymethamphetamine (ecstasy) and its major human metabolites act additively to induce significant toxicity to liver cells when combined at low, non-cytotoxic concentrations.
Topics: 3,4-Methylenedioxyamphetamine; Biotransformation; Cell Survival; Chemical and Drug Induced Liver Inj | 2014 |
[Acute liver failure caused by methylenedioxymethamphetamine ('ecstasy')].
Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Chemical and Drug Induced Liver Injury; Combined Modality | 1993 |
Chronic ecstasy (3,4-methylenedioxymetamphetamine) abuse: a recurrent and unpredictable cause of severe acute hepatitis.
Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adolescent; Adult; Biopsy; Chemical and Drug Induced L | 1996 |
Accidental intoxication with methylene dianiline p,p'-diaminodiphenylmethane: acute liver damage after presumed ecstasy consumption.
Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Adult; Aniline Compounds; Carcinogens; Chemical and Drug | 1997 |
Chemically-induced liver failure.
Topics: 3,4-Methylenedioxyamphetamine; Adolescent; Chemical and Drug Induced Liver Injury; Hallucinogens; Hu | 1998 |
Misuse of ecstasy.
Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Designe | 1992 |
Misuse of ecstasy.
Topics: 3,4-Methylenedioxyamphetamine; Acute Disease; Adult; Chemical and Drug Induced Liver Injury; Designe | 1992 |