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3,4-dihydroxyphenylglycol and Disease Models, Animal

3,4-dihydroxyphenylglycol has been researched along with Disease Models, Animal in 44 studies

*Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. [MeSH]

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19902 (4.55)18.7374
1990's3 (6.82)18.2507
2000's11 (25.00)29.6817
2010's26 (59.09)24.3611
2020's2 (4.55)2.80

Authors

AuthorsStudies
Han, DE; Li, HW; Li, KY; Ma, K; Tian, P; Zhang, W1
Cavallo, D; Gerace, E; Giovannini, MG; Henley, JM; Lana, D; Landucci, E; Pellegrini-Giampietro, DE; Ugolini, F1
Gao, SH; Ruan, HZ; Shen, LL; Wen, HZ; Zhao, YD1
Dronjak, S; Hoffmann, M; Jankovic, M; Jeremic, I; Jovanovic, P; Spasojevic, N; Stefanovic, B1
Carrier, N; Ding, XS; Duclot, F; Fang, XQ; Groveman, BR; Jiang, XH; Kabbaj, M; Qiao, H; Salter, MW; Wang, H; Wang, W; Xin, W; Yu, XM1
Appalsamy, M; Diedrich, A; Fentress, HM; Finney, C; Hahn, MK; Klar, R; Krueger, JJ; Lonce, S; Redmon, SN; Sabb, TR; Shirey-Rice, JK; Wallace, NM1
Berretta, N; Cavallucci, V; D'Amelio, M; Mercuri, NB; Nisticò, R; Nobili, A1
Cheng, AW; Dawlaty, MM; Faull, KF; Jaenisch, R; Le, T; Meng, J; Rudenko, A; Seo, J; Tsai, LH1
Battaglia, G; Bruno, V; Cannella, M; Catania, MV; Di Menna, L; Molinaro, G; Motolese, M; Nicoletti, F; Nisticò, R; Piccinin, S; Pignatelli, M; Riozzi, B; Vetere, G1
de Roos, B; Duthie, G; Fernández-Bolaños, J; Rodríguez-Gutiérrez, G; Rubio-Senent, F1
Cordeiro Matos, S; Séguéla, P; Zhang, Z1
Cruz-Santa, Y; De Jesús-Burgos, MI; González-García, S; Pérez-Acevedo, NL1
Janphet, S; Nudmamud-Thanoi, S; Thanoi, S1
Achuta, VS; Castrén, ML; Grym, H; Kärkkäinen, V; Koistinaho, J; Louhivuori, V; Putkonen, N; Roybon, L1
Banke, TG; Lundbye, CJ; Toft, AK1
Battaglia, G; Bruno, V; Caruso, A; Girardi, P; Gruber, SH; Marchiafava, M; Mathè, AA; Matrisciano, F; Melchiorri, D; Nicoletti, F; Orlando, R; Tatarelli, R1
Gerace, E; Landucci, E; Moroni, F; Pellegrini-Giampietro, DE; Scartabelli, T1
Hoeffer, CA; Klann, E; McBride, SM; Miyawaki, T; Sharma, A; Takayasu, Y; Zukin, RS1
Bassell, GJ; Chan, CB; Gross, C; Nakamoto, M; Warren, ST; Yao, X; Ye, K; Yim, SY1
Chen, SQ; Den, WY; Fan, HX; Gao, MM; Jiang, T; Su, T; Sun, WW; Yi, YH; Zhao, QH1
Bongmba, OY; Butler, K; Elhardt, ME; Martinez, LA; Tejada-Simon, MV1
Ji, G; Neugebauer, V1
Bernardi, G; Castelli, M; Centonze, D; De Chiara, V; Federici, M; Gu, HH; Mercuri, NB; Motta, C; Musella, A; Napolitano, F; Romano, R; Rossi, S; Sacchetti, L; Siracusano, A; Studer, V; Usiello, A1
Costa, AC; Scott-McKean, JJ1
Arbiser, JL; Bhattacharya, A; Chévere-Torres, I; Gambello, MJ; Kang, A; Kaphzan, H; Klann, E; Maki, JM; Santini, E1
Birnbaum, SG; Collins, KA; Gibson, JR; Guo, W; Hays, SA; Hu, JH; Huber, KM; Ronesi, JA; Tsai, NP; Worley, PF1
Gu, L; Sun, L; Wang, S; Yang, H; Yuan, J; Zhang, H; Zhu, J1
Cantlay, LL; de Roos, B; Duthie, GG; Fernández-Bolaños Guzmán, J; Horgan, GW; Kelder, T; Morrice, P; Nicol, F; Reid, M; Rodríguez-Gutiérrez, G; Wood, S1
Bozdagi, O; Buxbaum, JD; Dorr, N; Pilorge, M; Sakurai, T; Takahashi, N1
Alvarez-Dieppa, AC; Bhattacharya, A; Kaphzan, H; Klann, E; Murphy, JP; Pierre, P1
Bezprozvanny, I; Chan, EY; Hayden, MR; Maximov, A; Tang, TS; Tu, H; Wang, Z; Wellington, CL1
Albin, RL; Feeley Kearney, JA1
Imanishi, M; Kaneda, K; Kita, H; Nambu, A; Shigemoto, R; Tachibana, Y; Takada, M1
Hemptinne, I; Hermans, E; Maloteaux, JM; Tilleux, S; Vanhoutte, N; Vermeiren, C1
Huber, KM; Nosyreva, ED1
Bauer, M; Beck, H; Becker, AJ; Kirschstein, T; Müller, L; Reitze, M; Rüschenschmidt, C; Schoch, S1
Clinckers, R; Ebinger, G; Meurs, A; Michotte, Y; Smolders, I1
Chang, NC; Chen, CC; Lee, TM; Lin, MS1
Agari, T; Borlongan, CV; Date, I; Kondo, A; Kuramoto, S; Matsui, T; Miyoshi, Y; Shingo, T; Yasuhara, T1
Go, VL; Hadesman, R; Tyce, GM; Wiesner, RH1
Amrhein, P; Babin-Ebell, J; Elert, O; Kobelt, F; Silber, RE; Thees, SO1
Armando, I; Fukuhara, K; Goldstein, DS; Kopin, IJ; Kvetnansky, R; Pacak, K; Palkovits, M1
Hodsman, GP; Howes, LG; Johnston, CI; Kohzuki, M; Maccarrone, C1
Alsasua, A; Blanchart, A; López-Novoa, JM; Rodríguez-Puyol, D; Santos, JC1

Other Studies

44 other study(ies) available for 3,4-dihydroxyphenylglycol and Disease Models, Animal

ArticleYear
[Effect of Rehmanniae Radix on depression-like behavior and hippocampal monoamine neurotransmitters of chronic unpredictable mild stress model rats].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:17

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antidepressive Agents; Chromatography, Liquid; Depression; Disease Models, Animal; Dopamine; Eosine Yellowish-(YS); Hematoxylin; Hippocampus; Homovanillic Acid; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Monoamine Oxidase; Neurotransmitter Agents; Norepinephrine; Plant Extracts; Rats; Rehmannia; Serotonin; Serotonin Plasma Membrane Transport Proteins; Stress, Psychological; Tandem Mass Spectrometry; Tryptophan Hydroxylase

2022
Neuroprotective effects of mGluR5 activation through the PI3K/Akt pathway and the molecular switch of AMPA receptors.
    Neuropharmacology, 2020, 01-01, Volume: 162

    Topics: Allosteric Regulation; Animals; Brain Ischemia; CA1 Region, Hippocampal; Disease Models, Animal; Down-Regulation; Gliosis; In Vitro Techniques; Methoxyhydroxyphenylglycol; Neuroglia; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Piperidines; Proto-Oncogene Proteins c-akt; Rats; Receptor, Metabotropic Glutamate 5; Receptors, AMPA; Receptors, Metabotropic Glutamate

2020
Inhibition of Metabotropic Glutamate Receptor Subtype 1 Alters the Excitability of the Commissural Pyramidal Neuron in the Rat Anterior Cingulate Cortex after Chronic Constriction Injury to the Sciatic Nerve.
    Anesthesiology, 2017, Volume: 127, Issue:3

    Topics: Animals; Behavior, Animal; Blotting, Western; Chronic Disease; Constriction, Pathologic; Disease Models, Animal; Down-Regulation; Fluorescent Antibody Technique; Gyrus Cinguli; Male; Methoxyhydroxyphenylglycol; Neuralgia; Patch-Clamp Techniques; Pyramidal Cells; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sciatic Nerve

2017
Altered cardiac gene expression of noradrenaline enzymes, transporter and β-adrenoceptors in rat model of rheumatoid arthritis.
    Autonomic neuroscience : basic & clinical, 2017, Volume: 208

    Topics: Animals; Arthritis, Rheumatoid; Blotting, Western; Disease Models, Animal; Gene Expression; Male; Methoxyhydroxyphenylglycol; Monoamine Oxidase; Myocardium; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Rats; Real-Time Polymerase Chain Reaction; Receptors, Adrenergic, beta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Terpenes; Tyrosine 3-Monooxygenase

2017
Hippocampal protein kinase D1 is necessary for DHPG-induced learning and memory impairments in rats.
    PloS one, 2018, Volume: 13, Issue:4

    Topics: Animals; CA1 Region, Hippocampal; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Knockout Techniques; Hippocampus; Learning; Learning Disabilities; Locomotion; Male; Maze Learning; Memory; Memory Disorders; Methoxyhydroxyphenylglycol; Protein Kinase C; Rats; Spatial Memory

2018
Norepinephrine transporter variant A457P knock-in mice display key features of human postural orthostatic tachycardia syndrome.
    Disease models & mechanisms, 2013, Volume: 6, Issue:4

    Topics: Animals; Baroreflex; Behavior, Animal; Biological Transport; Catecholamines; Disease Models, Animal; Female; Gene Knock-In Techniques; Humans; Methoxyhydroxyphenylglycol; Mice; Mutant Proteins; Norepinephrine; Norepinephrine Plasma Membrane Transport Proteins; Postural Orthostatic Tachycardia Syndrome; Telemetry

2013
Calcineurin inhibition rescues early synaptic plasticity deficits in a mouse model of Alzheimer's disease.
    Neuromolecular medicine, 2013, Volume: 15, Issue:3

    Topics: Alzheimer Disease; Animals; CA1 Region, Hippocampal; Calcineurin Inhibitors; Caspase 3; Dendrites; Disease Models, Animal; Disks Large Homolog 4 Protein; Drug Evaluation, Preclinical; Excitatory Postsynaptic Potentials; Guanylate Kinases; Long-Term Synaptic Depression; Male; Membrane Proteins; Methoxyhydroxyphenylglycol; Mice; Mice, Transgenic; Neuroprotective Agents; Phosphorylation; Phosphoserine; Post-Synaptic Density; Protein Processing, Post-Translational; Receptors, AMPA; Receptors, Metabotropic Glutamate; Tacrolimus

2013
Tet1 is critical for neuronal activity-regulated gene expression and memory extinction.
    Neuron, 2013, Sep-18, Volume: 79, Issue:6

    Topics: Age Factors; Analysis of Variance; Animals; Anxiety; Basic Helix-Loop-Helix Transcription Factors; Cerebral Cortex; Conditioning, Classical; Depression; Disease Models, Animal; DNA-Binding Proteins; Exploratory Behavior; Extinction, Psychological; Gene Expression Profiling; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Locomotion; Long-Term Synaptic Depression; Male; Maze Learning; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurons; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fos; Receptors, N-Methyl-D-Aspartate; Synapses; Synapsins

2013
Changes in mGlu5 receptor-dependent synaptic plasticity and coupling to homer proteins in the hippocampus of Ube3A hemizygous mice modeling angelman syndrome.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014, Mar-26, Volume: 34, Issue:13

    Topics: Angelman Syndrome; Animals; Carrier Proteins; Disease Models, Animal; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Hemizygote; Hippocampus; Homer Scaffolding Proteins; Immunosuppressive Agents; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase Kinases; Pyridines; Receptor, Metabotropic Glutamate 5; Signal Transduction; Sirolimus; Ubiquitin-Protein Ligases

2014
Inhibitory and synergistic effects of natural olive phenols on human platelet aggregation and lipid peroxidation of microsomes from vitamin E-deficient rats.
    European journal of nutrition, 2015, Volume: 54, Issue:8

    Topics: Adult; Animals; Antioxidants; Disease Models, Animal; Female; Humans; Lipid Peroxidation; Male; Methoxyhydroxyphenylglycol; Microsomes; Middle Aged; Olea; Olive Oil; Phenols; Phenylethyl Alcohol; Plant Extracts; Platelet Aggregation; Rats; Vitamin E; Vitamin E Deficiency

2015
Peripheral Neuropathy Induces HCN Channel Dysfunction in Pyramidal Neurons of the Medial Prefrontal Cortex.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Sep-23, Volume: 35, Issue:38

    Topics: Animals; Biophysical Phenomena; Cyclic Nucleotide-Gated Cation Channels; Disease Models, Animal; Hyperalgesia; In Vitro Techniques; Male; Membrane Potentials; Methoxyhydroxyphenylglycol; Neuralgia; Pain Measurement; Pain Threshold; Prefrontal Cortex; Pyramidal Cells; Pyrimidines; Rats; Rats, Long-Evans; Sodium Channel Blockers; Synaptic Potentials; Tetrodotoxin

2015
Amygdalar activation of group I metabotropic glutamate receptors produces anti- and pro-conflict effects depending upon animal sex in a sexually dimorphic conditioned conflict-based anxiety model.
    Behavioural brain research, 2016, Apr-01, Volume: 302

    Topics: Amygdala; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Buprenorphine; Conditioning, Psychological; Conflict, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Estradiol; Female; Gene Expression Regulation; Male; Methoxyhydroxyphenylglycol; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Sex Characteristics

2016
Alteration of catecholamine concentrations in rat testis after methamphetamine exposure.
    Andrologia, 2017, Volume: 49, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Chromatography, High Pressure Liquid; Disease Models, Animal; Illicit Drugs; Male; Methamphetamine; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Reproduction; Testis

2017
Metabotropic glutamate receptor 5 responses dictate differentiation of neural progenitors to NMDA-responsive cells in fragile X syndrome.
    Developmental neurobiology, 2017, Volume: 77, Issue:4

    Topics: Animals; Cell Differentiation; Cerebral Cortex; Disease Models, Animal; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Female; Fragile X Syndrome; Humans; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; N-Methylaspartate; Neural Stem Cells; Pyridines; Receptor, Metabotropic Glutamate 5

2017
Dysregulated NMDA-Receptor Signaling Inhibits Long-Term Depression in a Mouse Model of Fragile X Syndrome.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 09-21, Volume: 36, Issue:38

    Topics: Age Factors; Animals; Biophysics; CA3 Region, Hippocampal; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Agents; Excitatory Postsynaptic Potentials; Fragile X Mental Retardation Protein; Fragile X Syndrome; In Vitro Techniques; Long-Term Synaptic Depression; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; Receptors, N-Methyl-D-Aspartate; Signal Transduction; Synapses

2016
Defective group-II metaboropic glutamate receptors in the hippocampus of spontaneously depressed rats.
    Neuropharmacology, 2008, Volume: 55, Issue:4

    Topics: Amino Acids; Animals; Antidepressive Agents, Tricyclic; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Clomipramine; Colforsin; Cyclic AMP; Depression; Disease Models, Animal; Drug Interactions; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Methoxyhydroxyphenylglycol; Rats; Receptors, Metabotropic Glutamate; RNA, Messenger; Swimming

2008
Neuroprotection by group I mGlu receptors in a rat hippocampal slice model of cerebral ischemia is associated with the PI3K-Akt signaling pathway: a novel postconditioning strategy?
    Neuropharmacology, 2008, Volume: 55, Issue:4

    Topics: Analysis of Variance; Animals; Animals, Newborn; Brain Ischemia; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Glutamic Acid; Hippocampus; Methoxyhydroxyphenylglycol; Oncogene Protein v-akt; Organ Culture Techniques; Phosphatidylinositol 3-Kinases; Propidium; Pyramidal Cells; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Signal Transduction; Time Factors

2008
Dysregulation of mTOR signaling in fragile X syndrome.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Jan-13, Volume: 30, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Animals; CA1 Region, Hippocampal; Carrier Proteins; Cell Cycle Proteins; Cognition Disorders; Disease Models, Animal; Eukaryotic Initiation Factor-4A; Eukaryotic Initiation Factors; Excitatory Postsynaptic Potentials; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation; Immunoprecipitation; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Receptors, Metabotropic Glutamate; Serine; Signal Transduction; Sirolimus

2010
Excess phosphoinositide 3-kinase subunit synthesis and activity as a novel therapeutic target in fragile X syndrome.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010, Aug-11, Volume: 30, Issue:32

    Topics: Analysis of Variance; Animals; Cells, Cultured; Class I Phosphatidylinositol 3-Kinases; Dendrites; Disease Models, Animal; Embryo, Mammalian; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation, Enzymologic; Green Fluorescent Proteins; Hippocampus; Humans; Immunoprecipitation; Luminescent Proteins; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Models, Biological; Neurons; Phosphatidylinositol 3-Kinases; Protein Subunits; Receptors, AMPA; Red Fluorescent Protein; RNA, Messenger; Synapses; Synaptosomes; Transfection

2010
Early continuous inhibition of group 1 mGlu signaling partially rescues dendritic spine abnormalities in the Fmr1 knockout mouse model for fragile X syndrome.
    Psychopharmacology, 2011, Volume: 215, Issue:2

    Topics: Age Factors; Analysis of Variance; Animals; Animals, Newborn; Benzopyrans; Cells, Cultured; Dendritic Spines; Disease Models, Animal; Fragile X Mental Retardation Protein; Fragile X Syndrome; Hippocampus; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Knockout; Neural Inhibition; Neurons; Pyridines; Receptors, Metabotropic Glutamate; Signal Transduction; Silver Staining

2011
Modulation of dendritic spines and synaptic function by Rac1: a possible link to Fragile X syndrome pathology.
    Brain research, 2011, Jul-05, Volume: 1399

    Topics: Aminoquinolines; Analysis of Variance; Animals; Brain; Dendrites; Dendritic Spines; Disease Models, Animal; Electric Stimulation; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation; In Vitro Techniques; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neurons; Patch-Clamp Techniques; Pyrimidines; rac1 GTP-Binding Protein; Signal Transduction; Silver Staining; Synapses

2011
Pain-related deactivation of medial prefrontal cortical neurons involves mGluR1 and GABA(A) receptors.
    Journal of neurophysiology, 2011, Volume: 106, Issue:5

    Topics: Action Potentials; Animals; Arthritis, Experimental; Benzoates; Bicuculline; Disease Models, Animal; Electrophysiology; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Male; Methoxyhydroxyphenylglycol; Neurons; Pain; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, GABA-A; Receptors, Metabotropic Glutamate

2011
Loss of striatal cannabinoid CB1 receptor function in attention-deficit / hyperactivity disorder mice with point-mutation of the dopamine transporter.
    The European journal of neuroscience, 2011, Volume: 34, Issue:9

    Topics: Animals; Attention Deficit Disorder with Hyperactivity; Cocaine; Corpus Striatum; Disease Models, Animal; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dronabinol; Excitatory Amino Acid Antagonists; Food Preferences; Gene Expression Regulation; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Point Mutation; Receptor, Cannabinoid, CB1; Receptors, GABA-B; Sucrose

2011
Exaggerated NMDA mediated LTD in a mouse model of Down syndrome and pharmacological rescuing by memantine.
    Learning & memory (Cold Spring Harbor, N.Y.), 2011, Volume: 18, Issue:12

    Topics: Analysis of Variance; Animals; Disease Models, Animal; Down Syndrome; Electric Stimulation; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Memantine; Methoxyhydroxyphenylglycol; Mice; Mice, Mutant Strains; N-Methylaspartate; Time Factors; Trisomy

2011
Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex.
    Neurobiology of disease, 2012, Volume: 45, Issue:3

    Topics: Analysis of Variance; Animals; Animals, Newborn; Biophysics; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Electric Stimulation; Enzyme Inhibitors; Excitatory Amino Acid Agents; GTPase-Activating Proteins; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; MAP Kinase Signaling System; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Patch-Clamp Techniques; Receptors, Metabotropic Glutamate; Ribosomal Protein S6 Kinases; Tuberous Sclerosis; Tuberous Sclerosis Complex 1 Protein; Tuberous Sclerosis Complex 2 Protein; Tumor Suppressor Proteins

2012
Disrupted Homer scaffolds mediate abnormal mGluR5 function in a mouse model of fragile X syndrome.
    Nature neuroscience, 2012, Jan-22, Volume: 15, Issue:3

    Topics: Analysis of Variance; Animals; Carrier Proteins; Cycloheximide; Disease Models, Animal; Electric Stimulation; Exploratory Behavior; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation; Hippocampus; Homer Scaffolding Proteins; Immunoprecipitation; In Vitro Techniques; Long-Term Potentiation; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Net; Patch-Clamp Techniques; Peptides; Physics; Protein Synthesis Inhibitors; Rats; Rats, Long-Evans; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Serine; Signal Transduction; TOR Serine-Threonine Kinases

2012
N-acetylcysteine protects against apoptosis through modulation of group I metabotropic glutamate receptor activity.
    PloS one, 2012, Volume: 7, Issue:3

    Topics: Acetylcysteine; Animals; Apoptosis; Cell Line; Cell Survival; Disease Models, Animal; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Free Radical Scavengers; Methoxyhydroxyphenylglycol; Oxidation-Reduction; Parkinson Disease; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptors, Metabotropic Glutamate; Staurosporine

2012
Alperujo extract, hydroxytyrosol, and 3,4-dihydroxyphenylglycol are bioavailable and have antioxidant properties in vitamin E-deficient rats--a proteomics and network analysis approach.
    Molecular nutrition & food research, 2012, Volume: 56, Issue:7

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Anticholesteremic Agents; Antioxidants; Diet; Dietary Supplements; Disease Models, Animal; Food-Processing Industry; Fruit; Hypolipidemic Agents; Industrial Waste; Intestinal Absorption; Liver; Male; Methoxyhydroxyphenylglycol; Mitochondrial Proteins; Olea; Oxidative Stress; Phenylethyl Alcohol; Plant Extracts; Random Allocation; Rats; Vitamin E Deficiency

2012
Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice.
    PloS one, 2012, Volume: 7, Issue:8

    Topics: Adaptor Proteins, Signal Transducing; Animals; Behavior, Animal; Disease Models, Animal; DNA Copy Number Variations; Excitatory Amino Acid Antagonists; Fragile X Syndrome; Gene Order; Genotype; Haploinsufficiency; Long-Term Potentiation; Long-Term Synaptic Depression; Male; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Nerve Tissue Proteins; Phenotype; Protein Biosynthesis; Receptors, Glutamate

2012
Genetic removal of p70 S6 kinase 1 corrects molecular, synaptic, and behavioral phenotypes in fragile X syndrome mice.
    Neuron, 2012, Oct-18, Volume: 76, Issue:2

    Topics: Analysis of Variance; Animals; Behavior, Animal; Biophysics; Dendritic Spines; Disease Models, Animal; Electric Stimulation; Excitatory Postsynaptic Potentials; Exploratory Behavior; Extracellular Signal-Regulated MAP Kinases; Female; Fragile X Mental Retardation Protein; Fragile X Syndrome; Gene Expression Regulation; Hippocampus; In Vitro Techniques; Interpersonal Relations; Long-Term Synaptic Depression; Male; Maze Learning; Membrane Potentials; Methoxyhydroxyphenylglycol; Mice; Mice, Inbred C57BL; Mice, Transgenic; Motor Activity; Mutation; Neurons; Patch-Clamp Techniques; Phenotype; Phosphorylation; Recognition, Psychology; Ribosomal Protein S6 Kinases, 70-kDa; Rotarod Performance Test; Synapses; TOR Serine-Threonine Kinases

2012
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1.
    Neuron, 2003, Jul-17, Volume: 39, Issue:2

    Topics: Action Potentials; Animals; Blotting, Western; Calcium; Calcium Channels; Calcium Signaling; Cells, Cultured; Cerebellum; Cerebral Cortex; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Fura-2; Green Fluorescent Proteins; Humans; Huntingtin Protein; Huntington Disease; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Lipid Bilayers; Luminescent Proteins; Methoxyhydroxyphenylglycol; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Patch-Clamp Techniques; Peptide Fragments; Plasmids; Protein Binding; Receptors, Cytoplasmic and Nuclear; Recombinant Proteins; Time Factors; Two-Hybrid System Techniques

2003
mGluRs: a target for pharmacotherapy in Parkinson disease.
    Experimental neurology, 2003, Volume: 184 Suppl 1

    Topics: Amino Acids, Dicarboxylic; Animals; Autoradiography; Basal Ganglia; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Excitatory Amino Acid Agonists; Glucose; Immunohistochemistry; Methoxyhydroxyphenylglycol; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Rats; Receptors, Metabotropic Glutamate

2003
Down-regulation of metabotropic glutamate receptor 1alpha in globus pallidus and substantia nigra of parkinsonian monkeys.
    The European journal of neuroscience, 2005, Volume: 22, Issue:12

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Action Potentials; Animals; Behavior, Animal; Benzoates; Cell Count; Disease Models, Animal; Down-Regulation; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Globus Pallidus; Glycine; Immunohistochemistry; Indans; Macaca fascicularis; Male; Methoxyhydroxyphenylglycol; Parkinsonian Disorders; Receptors, Metabotropic Glutamate; Severity of Illness Index; Substantia Nigra; Tyrosine 3-Monooxygenase

2005
Loss of metabotropic glutamate receptor-mediated regulation of glutamate transport in chemically activated astrocytes in a rat model of amyotrophic lateral sclerosis.
    Journal of neurochemistry, 2006, Volume: 96, Issue:3

    Topics: Amyotrophic Lateral Sclerosis; Animals; Animals, Genetically Modified; Aspartic Acid; Astrocytes; Blotting, Northern; Calcium; Carbachol; Cholinergic Agonists; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Excitatory Amino Acid Antagonists; Excitatory Amino Acid Transporter 2; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Glutamic Acid; Humans; Immunohistochemistry; Male; Methoxyhydroxyphenylglycol; Protein Kinase C; Pyridines; Rats; Receptor, Metabotropic Glutamate 5; Receptors, Metabotropic Glutamate; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sodium; Superoxide Dismutase; Tritium

2006
Metabotropic receptor-dependent long-term depression persists in the absence of protein synthesis in the mouse model of fragile X syndrome.
    Journal of neurophysiology, 2006, Volume: 95, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; Animals; Anisomycin; Blotting, Western; Disease Models, Animal; Drug Interactions; Electric Stimulation; Excitatory Amino Acid Antagonists; Fragile X Mental Retardation Protein; Fragile X Syndrome; Hippocampus; In Vitro Techniques; Long-Term Synaptic Depression; Methoxyhydroxyphenylglycol; Mice; Mice, Knockout; Neurons; Protein Biosynthesis; Protein Synthesis Inhibitors; Receptors, Metabotropic Glutamate

2006
Loss of metabotropic glutamate receptor-dependent long-term depression via downregulation of mGluR5 after status epilepticus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, Jul-18, Volume: 27, Issue:29

    Topics: Animals; Carrier Proteins; Disease Models, Animal; Dose-Response Relationship, Radiation; Down-Regulation; Electric Stimulation; Hippocampus; Homer Scaffolding Proteins; In Vitro Techniques; Long-Term Synaptic Depression; Male; Methoxyhydroxyphenylglycol; Neurons; Pilocarpine; Rats; Rats, Wistar; Receptors, Metabotropic Glutamate; Status Epilepticus

2007
Seizure activity and changes in hippocampal extracellular glutamate, GABA, dopamine and serotonin.
    Epilepsy research, 2008, Volume: 78, Issue:1

    Topics: Analysis of Variance; Animals; Behavior, Animal; Chromatography, Liquid; Disease Models, Animal; Dopamine; Electroencephalography; Extracellular Fluid; gamma-Aminobutyric Acid; Glutamic Acid; Hippocampus; Male; Methoxyhydroxyphenylglycol; Microdialysis; Picrotoxin; Pilocarpine; Rats; Rats, Wistar; Seizures; Serotonin; Statistics, Nonparametric; Time Factors

2008
Effect of endothelin receptor antagonists on ventricular susceptibility in postinfarcted rats.
    American journal of physiology. Heart and circulatory physiology, 2008, Volume: 294, Issue:4

    Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; Atrasentan; Blotting, Western; Bosentan; Cardiac Pacing, Artificial; Disease Models, Animal; Endothelin A Receptor Antagonists; Endothelin B Receptor Antagonists; Endothelin-1; GAP-43 Protein; Hemodynamics; Hydralazine; Immunohistochemistry; Male; Methoxyhydroxyphenylglycol; Myocardial Infarction; Myocardium; Nerve Growth Factor; Neurofilament Proteins; Norepinephrine; Polymerase Chain Reaction; Pyrrolidines; Rats; Rats, Wistar; Receptor, Endothelin A; Receptor, Endothelin B; RNA, Messenger; Sulfonamides; Sympathetic Nervous System; Time Factors; Tyrosine 3-Monooxygenase; Up-Regulation

2008
Intrapallidal metabotropic glutamate receptor activation in a rat model of Parkinson's disease: behavioral and histological analyses.
    Brain research, 2008, Apr-08, Volume: 1203

    Topics: Adrenergic Agents; Analysis of Variance; Animals; Behavior, Animal; Dioxolanes; Disease Models, Animal; Drug Interactions; Excitatory Amino Acid Antagonists; Female; Globus Pallidus; Methoxyhydroxyphenylglycol; Motor Activity; Oxidopamine; Parkinson Disease; Proto-Oncogene Proteins c-fos; Purines; Rats; Rats, Sprague-Dawley; Receptors, Metabotropic Glutamate; Substantia Nigra; Time Factors; Tyrosine 3-Monooxygenase

2008
Concentrations of 3,4-dihydroxyphenylalanine and catecholamines and metabolites in brain in an anhepatic model of hepatic encephalopathy.
    Journal of neurochemistry, 1995, Volume: 65, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Catecholamines; Dihydroxyphenylalanine; Disease Models, Animal; Dopamine; Hepatectomy; Hepatic Encephalopathy; Hydroxylation; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Oxidation-Reduction; Rats; Rats, Sprague-Dawley; Subcellular Fractions; Tissue Distribution

1995
Concentrations of catecholamines in transplanted hearts after extracorporeal perfusion and cold storage.
    Heart and vessels, 1995, Volume: 10, Issue:3

    Topics: Animals; Cold Temperature; Disease Models, Animal; Heart Transplantation; Lactates; Lactic Acid; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Organ Preservation; Perfusion; Pyruvates; Pyruvic Acid; Random Allocation; Swine; Swine, Miniature

1995
Noradrenergic activation in the paraventricular nucleus during acute and chronic immobilization stress in rats: an in vivo microdialysis study.
    Brain research, 1992, Aug-28, Volume: 589, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acute Disease; Animals; Chronic Disease; Dialysis; Disease Models, Animal; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Paraventricular Hypothalamic Nucleus; Random Allocation; Rats; Rats, Sprague-Dawley; Restraint, Physical; Stress, Physiological

1992
Cardiac 3,4-dihydroxyphenylethylene glycol (DHPG) and catecholamine levels in a rat model of left ventricular failure.
    Journal of cardiovascular pharmacology, 1989, Volume: 13, Issue:2

    Topics: Animals; Catecholamines; Coronary Vessels; Disease Models, Animal; Female; Glycols; Heart Failure; Methoxyhydroxyphenylglycol; Myocardium; Organ Size; Rats; Rats, Inbred Strains

1989
Plasma catecholamines and urinary excretion of their main metabolites in three models of portal hypertension.
    Clinical physiology and biochemistry, 1988, Volume: 6, Issue:6

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Disease Models, Animal; Dopamine; Homovanillic Acid; Hypertension, Portal; Liver Cirrhosis, Experimental; Male; Methoxyhydroxyphenylglycol; Norepinephrine; Rats; Rats, Inbred Strains; Vanilmandelic Acid

1988