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3,4-dihydroxyphenylacetic acid and Substance-Related Disorders

3,4-dihydroxyphenylacetic acid has been researched along with Substance-Related Disorders in 15 studies

3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.

Substance-Related Disorders: Disorders related to substance use or abuse.

Research Excerpts

ExcerptRelevanceReference
"The combined decrease in Ago2 and increases in Nurr1 and Pitx3 might represent some of the mechanisms that served to protect against accumbal TH regulation observed in morphine withdrawn rats, which may be critical for DA bioavailability to influence behaviour."1.39Morphine administration modulates expression of Argonaute 2 and dopamine-related transcription factors involved in midbrain dopaminergic neurons function. ( García-Pérez, D; Laorden, ML; Milanés, MV; Núñez, C; Sáez-Belmonte, F, 2013)
" Taken together, our data indicate that chronic use of stanozolol significantly affects brain monoamines leading to neurochemical modifications possibly involved in depression and stress-related states."1.38Neurochemical consequence of steroid abuse: stanozolol-induced monoaminergic changes. ( Colaianna, M; Cuomo, V; Morgese, MG; Schiavone, S; Trabace, L; Tucci, P; Zotti, M, 2012)
"5-h intervals) 12 h prior to the MDMA dosing regimen (20 mg/kg x 3 at 2-h intervals) aggravated the MDMA-induced dopaminergic toxicity."1.35Ketamine pretreatment exacerbated 3,4-methylenedioxymethamphetamine-induced central dopamine toxicity. ( Cherng, CG; Ho, MC; Ke, JJ; Tsai, CW; Tsai, YP; Yu, L, 2008)
"We have demonstrated that chronic administration of neuropeptide FF (NPFF) into the lateral ventricle potentiated the behavioral sensitization to amphetamine."1.30Neuropeptide FF potentiates the behavioral sensitization to amphetamine and alters the levels of neurotransmitters in the medial prefrontal cortex. ( Chen, JC; Huang, YK; Li, JY; Liang, KW, 1999)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19901 (6.67)18.7374
1990's5 (33.33)18.2507
2000's4 (26.67)29.6817
2010's5 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Krasnova, IN1
Chiflikyan, M1
Justinova, Z1
McCoy, MT1
Ladenheim, B1
Jayanthi, S1
Quintero, C1
Brannock, C1
Barnes, C1
Adair, JE1
Lehrmann, E1
Kobeissy, FH1
Gold, MS1
Becker, KG1
Goldberg, SR1
Cadet, JL1
Rodríguez-Arias, M1
Valverde, O1
Daza-Losada, M1
Blanco-Gandía, MC1
Aguilar, MA1
Miñarro, J1
Ke, JJ1
Ho, MC1
Cherng, CG1
Tsai, YP1
Tsai, CW1
Yu, L1
Tucci, P1
Morgese, MG1
Colaianna, M1
Zotti, M1
Schiavone, S1
Cuomo, V1
Trabace, L1
García-Pérez, D1
Sáez-Belmonte, F1
Laorden, ML1
Núñez, C1
Milanés, MV1
Okamoto, R1
Itoh, Y1
Murata, Y1
Kobayashi, D1
Hosoi, M1
Mine, K1
Gardner, EL1
Liu, X1
Paredes, W1
Giordano, A1
Spector, J1
Lepore, M1
Wu, KM1
Froimowitz, M1
Birgner, C1
Kindlundh-Högberg, AM1
Nyberg, F1
Bergström, L1
Chen, JC1
Li, JY1
Liang, KW1
Huang, YK1
Scearce-Levie, K1
Chen, JP1
Gardner, E1
Hen, R1
Drouin, C1
Darracq, L1
Trovero, F1
Blanc, G1
Glowinski, J1
Cotecchia, S1
Tassin, JP1
See, RE1
Adams-Curtis, L1
Chapman, MA1
Piazza, PV1
Rougé-Pont, F1
Deminière, JM1
Kharoubi, M1
Le Moal, M1
Simon, H1
Clarren, SK1
Astley, SJ1
Bowden, DM1
Lai, H1
Milam, AH1
Rudeen, PK1
Shoemaker, WJ1
Seiden, LS1

Other Studies

15 other studies available for 3,4-dihydroxyphenylacetic acid and Substance-Related Disorders

ArticleYear
CREB phosphorylation regulates striatal transcriptional responses in the self-administration model of methamphetamine addiction in the rat.
    Neurobiology of disease, 2013, Volume: 58

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Central Nervous System Stimulants; Conditioning, Operant; C

2013
Assessment of the abuse potential of MDMA in the conditioned place preference paradigm: role of CB1 receptors.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Dec-02, Volume: 47

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Brain; Conditioning, Operant; Disease

2013
Ketamine pretreatment exacerbated 3,4-methylenedioxymethamphetamine-induced central dopamine toxicity.
    The Chinese journal of physiology, 2008, Apr-30, Volume: 51, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transpo

2008
Neurochemical consequence of steroid abuse: stanozolol-induced monoaminergic changes.
    Steroids, 2012, Volume: 77, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Depression; Dopamine; Hippocampus; Homovan

2012
Morphine administration modulates expression of Argonaute 2 and dopamine-related transcription factors involved in midbrain dopaminergic neurons function.
    British journal of pharmacology, 2013, Volume: 168, Issue:8

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Argonaute Proteins; Body Weight; Dopamine; Drug Implants; G

2013
Reduction of group II metabotropic glutamate receptors during development of benzodiazepine dependence.
    Pharmacology, 2013, Volume: 91, Issue:3-4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzodiazepines; Cerebral Cortex; Dopamine; Flumazenil; GAB

2013
A slow-onset, long-duration indanamine monoamine reuptake inhibitor as a potential maintenance pharmacotherapy for psychostimulant abuse: effects in laboratory rat models relating to addiction.
    Neuropharmacology, 2006, Volume: 51, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Cocaine; Dialysis;

2006
Altered extracellular levels of DOPAC and HVA in the rat nucleus accumbens shell in response to sub-chronic nandrolone administration and a subsequent amphetamine challenge.
    Neuroscience letters, 2007, Jan-29, Volume: 412, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Anabolic Agents; Animals; Dopamine; Dopamine Uptake Inh

2007
Neuropeptide FF potentiates the behavioral sensitization to amphetamine and alters the levels of neurotransmitters in the medial prefrontal cortex.
    Brain research, 1999, Jan-16, Volume: 816, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Dopamine; Drug Synergism; Hippocampus; Homovan

1999
5-HT receptor knockout mice: pharmacological tools or models of psychiatric disorders.
    Annals of the New York Academy of Sciences, 1999, Apr-30, Volume: 868

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Behavior, Animal; Cocaine; Disease Models, Anim

1999
Alpha1b-adrenergic receptors control locomotor and rewarding effects of psychostimulants and opiates.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, Apr-01, Volume: 22, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Animals; Brain; Central Nervous System

2002
Assessment of dopamine release by in vivo microdialysis in the nucleus accumbens of rats following acute and chronic administration of desipramine.
    Annals of the New York Academy of Sciences, 1992, Jun-28, Volume: 654

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Desipramine; Dialysis; Dopamine; Homovanillic Acid; Hydroxy

1992
Dopaminergic activity is reduced in the prefrontal cortex and increased in the nucleus accumbens of rats predisposed to develop amphetamine self-administration.
    Brain research, 1991, Dec-13, Volume: 567, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Cerebral Cortex; Corpus Striatum; Dopamine; Hy

1991
Neuroanatomic and neurochemical abnormalities in nonhuman primate infants exposed to weekly doses of ethanol during gestation.
    Alcoholism, clinical and experimental research, 1990, Volume: 14, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Brain; Corpus Striatum; Ethanol; Eye; Fem

1990
Methamphetamine: toxicity to dopaminergic neurons.
    NIDA research monograph, 1985, Volume: 62

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; Guinea Pigs; Hydroxydopamines; K

1985