3,4-dihydroxyphenylacetic acid has been researched along with Protein Aggregation, Pathological in 2 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Protein Aggregation, Pathological: A biochemical phenomenon in which misfolded proteins aggregate either intra- or extracellularly. Triggered by factors such as MUTATION; POST-TRANSLATIONAL MODIFICATIONS, and environmental stress, it is generally associated with ALZHEIMER DISEASE; PARKINSON DISEASE; HUNTINGTON DISEASE; and TYPE 2 DIABETES MELLITUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although this effect occurs with the formation of differently toxic products, the molecular basis of this inhibition is still unclear." | 1.62 | Structural Features and Toxicity of α-Synuclein Oligomers Grown in the Presence of DOPAC. ( Acquasaliente, L; Bucciantini, M; Fongaro, B; Leri, M; Palazzi, L; Polverino de Laureto, P; Stefani, M, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Palazzi, L | 1 |
| Fongaro, B | 1 |
| Leri, M | 1 |
| Acquasaliente, L | 1 |
| Stefani, M | 1 |
| Bucciantini, M | 1 |
| Polverino de Laureto, P | 1 |
| Plotegher, N | 1 |
| Berti, G | 1 |
| Ferrari, E | 1 |
| Tessari, I | 1 |
| Zanetti, M | 1 |
| Lunelli, L | 1 |
| Greggio, E | 1 |
| Bisaglia, M | 1 |
| Veronesi, M | 1 |
| Girotto, S | 1 |
| Dalla Serra, M | 1 |
| Perego, C | 1 |
| Casella, L | 1 |
| Bubacco, L | 1 |
2 other studies available for 3,4-dihydroxyphenylacetic acid and Protein Aggregation, Pathological
| Article | Year |
|---|---|
Structural Features and Toxicity of α-Synuclein Oligomers Grown in the Presence of DOPAC.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Amyloid; Cell Proliferation; Dopamine; Dopaminergic | 2021 |
DOPAL derived alpha-synuclein oligomers impair synaptic vesicles physiological function.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Synuclein; Animals; Biological Transport; Cell Line; Cell Memb | 2017 |