3,4-dihydroxyphenylacetic acid has been researched along with Pregnancy in 151 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we tested whether development of behavioral sensitization to cocaine before pregnancy affects the neural response to pups during the early postpartum days (PD)." | 7.74 | Development of cocaine sensitization before pregnancy affects subsequent maternal retrieval of pups and prefrontal cortical activity during nursing. ( Febo, M; Ferris, CF, 2007) |
| "During late pregnancy, the antiprogesterone mifepristone facilitates prolactin release." | 7.73 | Dopaminergic mechanisms involved in prolactin release after mifepristone and naloxone treatment during late pregnancy in the rat. ( Bregonzio, C; Deis, RP; Penissi, A; Soaje, M; Valdez, S, 2006) |
| "The relationships between self-reported assessments of the quality of the preoperative night's sleep, preoperative anxiety, and several biochemical and physiological indicators of stress reaction were investigated in pregnant women at term receiving no premedication (n = 15), a placebo tablet (n = 15), diazepam 5 mg p." | 5.07 | Diazepam and atropine as premedicants: no discrimination by monoamine metabolite and catecholamine measurements in cerebrospinal fluid and plasma. ( Kanto, J; Scheinin, M, 1992) |
| " In the present study, we tested whether development of behavioral sensitization to cocaine before pregnancy affects the neural response to pups during the early postpartum days (PD)." | 3.74 | Development of cocaine sensitization before pregnancy affects subsequent maternal retrieval of pups and prefrontal cortical activity during nursing. ( Febo, M; Ferris, CF, 2007) |
| "During late pregnancy, the antiprogesterone mifepristone facilitates prolactin release." | 3.73 | Dopaminergic mechanisms involved in prolactin release after mifepristone and naloxone treatment during late pregnancy in the rat. ( Bregonzio, C; Deis, RP; Penissi, A; Soaje, M; Valdez, S, 2006) |
| "Chronic gestational cocaine administration has been correlated with high levels of postpartum maternal aggression towards intruders and altered levels of oxytocin in the amygdala." | 3.72 | Effects of chronic cocaine on monoamine levels in discrete brain structures of lactating rat dams. ( Black, MC; Brown, LE; Cannon, JB; Johns, JM; Lubin, DA, 2003) |
| "Children whose mothers used cocaine during pregnancy appear to have an increased incidence of certain neurobehavioral deficits." | 3.71 | Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress. ( Elsworth, JD; Morrow, BA; Roth, RH, 2001) |
| "The present study was designed to examine more fully the neurochemical and behavioral interactions that derive from continued lead and cadmium poisoning in pups, whose mothers were exposed via drinking water (300 mg/l of Pb and 10 mg/l of Cd) throughout pregnancy and lactation." | 3.71 | Pb and Cd poisoning during development alters cerebellar and striatal function in rats. ( Antonio, MT; Leret, ML; López, N, 2002) |
| "The present study was undertaken in order to study the effects of perinatal asphyxia on tyrosine hydroxylase (TH) activity, dopamine levels and turnover, and dopamine metabolites (3,4-dihydroxyphenylacetic acid, DOPAC, homovanillic acid, HVA, and 3-methoxytyramine, 3-MT, analyzed by high-performance liquid chromatography, HPLC) measured in the basal ganglia of the 20- to 40-min-old newborn and 4-week-old male rat." | 3.69 | Effects of perinatal asphyxia on the mesostriatal/mesolimbic dopamine system of neonatal and 4-week-old male rats. ( Andersson, K; Bjelke, B; Bolme, P; Chen, Y; Eneroth, P; Gross, J; Heldt, J; Herrera-Marschitz, M; Loidl, CF; Ungethüm, U, 1996) |
| " In addition, the exposure to new environmental condition elevated blood corticosterone levels and enhanced behavioral activities to a greater extent in the Dex group than in controls at 7 wk of life, suggesting that elevated glucocorticoid levels during the pregnancy mimicked prenatal mild stress, producing developmental alterations in brain monoamine metabolism, endocrine response, and behavior in adult offspring." | 3.69 | Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring. ( Kamei, K; Kitera, K; Mikuni, M; Muneoka, K; Ogawa, T; Takahashi, K; Takigawa, M, 1997) |
| "To determine the usefulness of catecholamine (CA) levels in the evaluation of fetal distress during delivery, norepinephrine (NE), its intermediate metabolite 3,4-dihydroxyphenylethyleneglycol (DOPEG), and 3,4-dihydroxyphenylacetic acid (DOPAC), which is the main intermediate metabolite of dopamine (DA), were simultaneously measured in umbilical arterial and venous blood (UA, UV) and in maternal venous blood (MV)." | 3.68 | [Studies on catecholamine and its metabolites in the evaluation of fetal distress]. ( Shirai, T, 1992) |
| " The dopaminergic turnover was measured by 3,4-dihyroxyphenilacetic acid content and 3H-Spiperone binding has been carried out to determine dopaminergic receptor alterations induced by chronic ethanol consumption during pregnancy." | 3.66 | Effects of ethanol, given during pregnancy, on the offspring dopaminergic system. ( Covelli, V; Lucchi, L; Petkov, VV; Spano, PF; Trabucchi, M, 1983) |
| "The diazepam-treated patients had also smaller CSF concentrations of noradrenaline (NA) and of the dopamine metabolite, 3,4-dihydroxyphenylacetic acid (DOPAC)." | 2.67 | Biochemical assessment of preoperative stress: a study with diazepam and measurement of monoamine metabolites and catecholamines in cerebrospinal fluid and plasma. ( Kanto, J; Scheinin, M, 1991) |
| "Schizophrenia is probably ascribed to perinatal neurodevelopmental deficits, and its onset might be affected by environmental factors." | 1.62 | Preventive role of regular low-intensity exercise during adolescence in schizophrenia model mice with abnormal behaviors. ( Hata, T; Hiraga, T; Koizumi, H; Mouri, A; Nabeshima, T; Oharomari, LK; Okamoto, M; Shima, T; Soya, H; Yook, JS, 2021) |
| " Here, we employ the same alcohol dosing regimen, where zebrafish eggs are immersed into 0% or 1% (vol/vol) alcohol for 2 h, but we perform the immersion at 5, 10, 16, 24, 36, or 48 hpf." | 1.56 | Developmental stage-dependent deficits induced by embryonic ethanol exposure in zebrafish: A neurochemical analysis. ( Bailleul, C; Chatterjee, D; Facciol, A; Gerlai, R; Nguyen, S, 2020) |
| "Idiopathic Parkinson's disease (PD) is a neurodegenerative disorder of mature and older individuals." | 1.36 | Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration. ( Charlton, CG; King, J; Mackey, V; Muthian, G, 2010) |
| "Bisphenol A (BPA) is an endocrine-disrupting chemical, widely used in industry and dentistry." | 1.36 | Prenatal and lactational exposure to low-doses of bisphenol A alters brain monoamine concentration in adult mice. ( Fushiki, S; Itoh, K; Nakamura, K; Sugimoto, T; Yoshimoto, K, 2010) |
| " Acute or chronic administration of methamphetamine elevates the levels of the extracellular monoamine neurotransmitters, such as dopamine." | 1.35 | Prenatal methamphetamine exposure affects the mesolimbic dopaminergic system and behavior in adult offspring. ( Bubenikova-Valesova, V; Hruba, L; Janovsky, M; Kacer, P; Rambousek, L; Schutova, B; Slamberova, R; Syslova, K, 2009) |
| " A treatment history of high AMPH dosage was associated with a marked sensitization of the exploratory behavior in adults, whereas it induced a quite opposite profile in periadolescents." | 1.31 | Striatal dopamine sensitization to D-amphetamine in periadolescent but not in adult rats. ( Laviola, G; Pascucci, T; Pieretti, S, 2001) |
| " Protection was more profound with an acute dosing regimen than with daily MPTP administration over 5 d." | 1.30 | 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2. ( Beal, MF; Hyman, BT; Klockgether, T; Liao, AW; Martinou, JC; Matthews, RT; Penney, JB; Schulz, JB; Yang, L, 1998) |
| "The haloperidol-induced increase in DOPAC and HVA was less intense in primiparous rats than that in nulliparous ovariectomized rats." | 1.30 | Reproductive experience reduces striatal dopaminergic responses in freely moving female rats. ( Cruz-Casallas, PE; Felicio, LF; Florio, JC; Hucke, EE, 1998) |
| "Styrene was evaluated to determine its neurochemical effects in the offspring of rats exposed during the gestation period." | 1.30 | Effects of prenatal exposure to styrene on neurochemical levels in rat brain. ( Ikeda, T; Katakura, Y; Kishi, R; Miyake, H, 1999) |
| "Fetal hypoxia was induced in four monkeys by occlusion of the umbilical cord with a hydraulic occluder for 5-6 min." | 1.29 | Acute effects of perinatal hypoxic insult on concentrations of dopamine, serotonin, and metabolites in fetal monkey brain. ( Ali, SF; Binienda, Z; Fogle, CM; Slikker, W, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 34 (22.52) | 18.7374 |
| 1990's | 52 (34.44) | 18.2507 |
| 2000's | 44 (29.14) | 29.6817 |
| 2010's | 18 (11.92) | 24.3611 |
| 2020's | 3 (1.99) | 2.80 |
| Authors | Studies |
|---|---|
| Facciol, A | 1 |
| Bailleul, C | 1 |
| Nguyen, S | 1 |
| Chatterjee, D | 2 |
| Gerlai, R | 1 |
| Yao, J | 1 |
| Wang, J | 1 |
| Wu, L | 1 |
| Lu, H | 1 |
| Wang, Z | 1 |
| Yu, P | 1 |
| Xiao, H | 1 |
| Gao, R | 1 |
| Yu, J | 2 |
| Koizumi, H | 1 |
| Hiraga, T | 1 |
| Oharomari, LK | 1 |
| Hata, T | 1 |
| Shima, T | 1 |
| Yook, JS | 1 |
| Okamoto, M | 1 |
| Mouri, A | 1 |
| Nabeshima, T | 1 |
| Soya, H | 1 |
| Sun, Y | 2 |
| Li, YS | 1 |
| Li, B | 2 |
| Ma, K | 1 |
| Li, BX | 1 |
| Dutra-Tavares, AC | 1 |
| Silva, JO | 1 |
| Nunes-Freitas, AL | 1 |
| Guimarães, VMS | 1 |
| Araújo, UC | 1 |
| Conceição, EPS | 1 |
| Moura, EG | 1 |
| Lisboa, PC | 1 |
| Filgueiras, CC | 1 |
| Manhães, AC | 1 |
| Abreu-Villaça, Y | 1 |
| Ribeiro-Carvalho, A | 1 |
| Blecharz-Klin, K | 1 |
| Wawer, A | 1 |
| Pyrzanowska, J | 1 |
| Piechal, A | 1 |
| Jawna-Zboińska, K | 1 |
| Widy-Tyszkiewicz, E | 1 |
| Sai, T | 1 |
| Uchida, K | 1 |
| Nakayama, H | 1 |
| Huang, Y | 1 |
| Chen, S | 1 |
| Xu, H | 1 |
| Yu, X | 1 |
| Lai, H | 2 |
| Ho, G | 1 |
| Huang, Q | 1 |
| Shi, X | 1 |
| Rose, KM | 1 |
| Parmar, MS | 1 |
| Cavanaugh, JE | 1 |
| Li, Y | 1 |
| Yang, J | 1 |
| Wu, Y | 1 |
| Pannia, E | 1 |
| Cho, CE | 1 |
| Kubant, R | 1 |
| Sánchez-Hernández, D | 1 |
| Huot, PS | 1 |
| Fleming, A | 1 |
| Anderson, GH | 1 |
| Walters, JL | 1 |
| Lansdell, TA | 1 |
| Lookingland, KJ | 1 |
| Baker, LE | 1 |
| Ratajczak, P | 1 |
| Kus, K | 1 |
| Gołembiowska, K | 1 |
| Noworyta-Sokołowska, K | 1 |
| Woźniak, A | 1 |
| Zaprutko, T | 1 |
| Nowakowska, E | 1 |
| Larsen, TR | 1 |
| Rossen, S | 1 |
| Gramsbergen, JB | 1 |
| Winter, C | 1 |
| Djodari-Irani, A | 1 |
| Sohr, R | 1 |
| Morgenstern, R | 1 |
| Feldon, J | 1 |
| Juckel, G | 1 |
| Meyer, U | 1 |
| Yokota, S | 1 |
| Mizuo, K | 1 |
| Moriya, N | 1 |
| Oshio, S | 1 |
| Sugawara, I | 1 |
| Takeda, K | 1 |
| Ling, Z | 1 |
| Zhu, Y | 1 |
| Tong, CW | 1 |
| Snyder, JA | 1 |
| Lipton, JW | 1 |
| Carvey, PM | 2 |
| Coe, CL | 1 |
| Lubach, GR | 2 |
| Bianco, L | 1 |
| Beard, JL | 1 |
| Malanga, CJ | 1 |
| Ren, JQ | 1 |
| Guerriero, RM | 1 |
| Kosofsky, BE | 1 |
| Kesby, JP | 1 |
| Cui, X | 1 |
| Ko, P | 1 |
| McGrath, JJ | 1 |
| Burne, TH | 1 |
| Eyles, DW | 1 |
| Bubenikova-Valesova, V | 1 |
| Kacer, P | 1 |
| Syslova, K | 1 |
| Rambousek, L | 1 |
| Janovsky, M | 1 |
| Schutova, B | 1 |
| Hruba, L | 1 |
| Slamberova, R | 1 |
| Berlin, I | 1 |
| Heilbronner, C | 1 |
| Georgieu, S | 1 |
| Meier, C | 1 |
| Launay, JM | 1 |
| Spreux-Varoquaux, O | 1 |
| Nowak, P | 2 |
| Kostrzewa, RA | 1 |
| Skaba, D | 1 |
| Kostrzewa, RM | 2 |
| Muthian, G | 1 |
| Mackey, V | 1 |
| King, J | 1 |
| Charlton, CG | 1 |
| Nakamura, K | 1 |
| Itoh, K | 1 |
| Yoshimoto, K | 1 |
| Sugimoto, T | 1 |
| Fushiki, S | 1 |
| Bonafede, MM | 1 |
| Valdez, SR | 2 |
| Arboccó, FC | 1 |
| Pennacchio, GE | 1 |
| Soaje, M | 2 |
| Jahn, GA | 2 |
| Ugrumov, MV | 1 |
| Saifetyarova, JY | 1 |
| Lavrentieva, AV | 1 |
| Sapronova, AY | 1 |
| Matsuda, S | 1 |
| Matsuzawa, D | 1 |
| Ishii, D | 1 |
| Tomizawa, H | 1 |
| Sutoh, C | 1 |
| Nakazawa, K | 1 |
| Amano, K | 1 |
| Sajiki, J | 1 |
| Shimizu, E | 1 |
| Perna, MK | 1 |
| Brown, RW | 1 |
| Andrews, ZB | 2 |
| Grattan, DR | 2 |
| Lubin, DA | 2 |
| Cannon, JB | 1 |
| Black, MC | 1 |
| Brown, LE | 1 |
| Johns, JM | 2 |
| Sider, LH | 2 |
| Hucke, EE | 2 |
| Florio, JC | 4 |
| Felicio, LF | 5 |
| Phillips, PE | 1 |
| Budygin, EA | 2 |
| Gainetdinov, RR | 2 |
| Lieberman, JA | 1 |
| Wightman, RM | 1 |
| Dietz, DM | 1 |
| Pletnikov, MV | 2 |
| Alquicer, G | 1 |
| Silva-Gómez, AB | 1 |
| Peralta, F | 1 |
| Flores, G | 1 |
| Youngblood, RC | 1 |
| Filipov, NM | 1 |
| Rude, BJ | 1 |
| Christiansen, DL | 1 |
| Hopper, RM | 1 |
| Gerard, PD | 1 |
| Hill, NS | 1 |
| Fitzgerald, BP | 1 |
| Ryan, PL | 1 |
| Galineau, L | 1 |
| Belzung, C | 1 |
| Kodas, E | 1 |
| Bodard, S | 1 |
| Guilloteau, D | 1 |
| Chalon, S | 1 |
| McArthur, S | 1 |
| McHale, E | 1 |
| Dalley, JW | 1 |
| Buckingham, JC | 1 |
| Gillies, GE | 1 |
| Aldridge, JE | 1 |
| Meyer, A | 1 |
| Seidler, FJ | 2 |
| Slotkin, TA | 2 |
| Kreider, ML | 1 |
| Tate, CA | 1 |
| Yim, AJ | 1 |
| Miranda-Paiva, CM | 1 |
| Oliveira, CA | 1 |
| Nasello, AG | 2 |
| Sivam, SP | 1 |
| Cox, J | 1 |
| Sullivan, RM | 1 |
| Dufresne, MM | 1 |
| Tsunoda, M | 1 |
| Aizawa, Y | 1 |
| Konno, N | 1 |
| Kimura, K | 1 |
| Sugita-Konishi, Y | 1 |
| Gómez, C | 2 |
| Briñón, JG | 2 |
| Colado, MI | 2 |
| Orio, L | 2 |
| Vidal, M | 1 |
| Barbado, MV | 1 |
| Alonso, JR | 2 |
| Wagner, GC | 2 |
| Reuhl, KR | 1 |
| Ming, X | 1 |
| Halladay, AK | 2 |
| Valdez, S | 1 |
| Bregonzio, C | 2 |
| Penissi, A | 1 |
| Deis, RP | 2 |
| Valero, J | 1 |
| Recio, JS | 1 |
| Murias, AR | 1 |
| Curto, GG | 1 |
| Bortel, A | 1 |
| Dabrowska, J | 1 |
| Oswiecimska, J | 1 |
| Drosik, M | 1 |
| Kwiecinski, A | 1 |
| Opara, J | 1 |
| Brus, R | 1 |
| Penissi, AB | 1 |
| Febo, M | 1 |
| Ferris, CF | 1 |
| Naef, L | 1 |
| Srivastava, L | 1 |
| Gratton, A | 1 |
| Hendrickson, H | 1 |
| Owens, SM | 1 |
| Walker, CD | 1 |
| Romero, E | 1 |
| Guaza, C | 1 |
| Castellano, B | 1 |
| Borrell, J | 1 |
| Simpkins, JW | 1 |
| Lasley, SM | 2 |
| Greenland, RD | 2 |
| Minnema, DJ | 2 |
| Michaelson, IA | 2 |
| DeLisi, LE | 1 |
| Mirsky, AF | 1 |
| Buchsbaum, MS | 1 |
| van Kammen, DP | 1 |
| Berman, KF | 1 |
| Caton, C | 1 |
| Kafka, MS | 1 |
| Ninan, PT | 1 |
| Phelps, BH | 1 |
| Karoum, F | 1 |
| Govoni, S | 1 |
| Memo, M | 3 |
| Lucchi, L | 4 |
| Spano, PF | 4 |
| Trabucchi, M | 4 |
| Covelli, V | 1 |
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| Rossetti, ZL | 1 |
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| Henderson, MG | 1 |
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| Holson, RR | 1 |
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| Bowyer, JF | 1 |
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| Alonso, SJ | 1 |
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| Herrera-Marschitz, M | 2 |
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| Bjelke, B | 2 |
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| Meyer, JS | 1 |
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| Weese-Mayer, DE | 1 |
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| Kudrin, VS | 1 |
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| Ostrovskaia, RU | 1 |
| Cruz-Casallas, PE | 2 |
| Bridges, RS | 1 |
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| Lagercrantz, H | 1 |
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| Laviola, G | 1 |
| Pascucci, T | 1 |
| Pieretti, S | 1 |
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| Riaz, SS | 1 |
| Jauniaux, E | 1 |
| Stern, GM | 1 |
| Bradford, HF | 1 |
| Kokay, IC | 1 |
| Devoto, P | 1 |
| Flore, G | 1 |
| Ibba, A | 1 |
| Fratta, W | 1 |
| Pani, L | 1 |
| Elsworth, JD | 1 |
| Morrow, BA | 1 |
| Roth, RH | 1 |
| Lee, BC | 1 |
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| Wagner, HR | 1 |
| Doepfner, W | 1 |
| Rodríguez de Fonseca, F | 1 |
| Hernández, ML | 1 |
| Kanto, J | 3 |
| Scheinin, M | 3 |
| Santana, C | 1 |
| Afonso, D | 2 |
| Arevalo, R | 1 |
| Trinidad Herrero, M | 1 |
| Shirai, T | 1 |
| Beyer, C | 1 |
| Pilgrim, C | 1 |
| Reisert, I | 1 |
| Castellanos, MA | 1 |
| Scheinin, H | 1 |
| Ekblad, U | 1 |
| Ohya, Y | 1 |
| Naoi, M | 1 |
| Ochi, N | 1 |
| Mizutani, N | 1 |
| Watanabe, K | 2 |
| Nagatsu, T | 1 |
| Mistry, AM | 1 |
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| Voogt, JL | 2 |
| Ishizuka, B | 1 |
| Hirata, K | 1 |
| Matsumoto, K | 1 |
| Ohno, Y | 1 |
| Kondoh, T | 1 |
| Horikoshi, H | 1 |
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| Hamada, H | 1 |
| Clarren, SK | 1 |
| Astley, SJ | 1 |
| Bowden, DM | 1 |
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| Russell, VA | 1 |
| de Villiers, AS | 1 |
| Searson, JA | 1 |
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| Ribary, U | 2 |
| Schlumpf, M | 2 |
| Lichtensteiger, W | 2 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Monoamines Oxidases A and B Activities and the Metabolism of Nicotine in Smoking and Nonsmoking Pregnant Women and in Their Newborns. Evaluation of Their Effects on the Newborns' Behavior[NCT00169390] | 59 participants (Actual) | Observational | 2004-03-31 | Completed | |||
| A Randomized Controlled Trial of Adjunctive Siltuximab in Schizophrenia[NCT02796859] | Phase 1/Phase 2 | 30 participants (Anticipated) | Interventional | 2016-05-31 | Recruiting | ||
| An Open-Label Trial of Tocilizumab in Schizophrenia[NCT01696929] | Phase 1 | 8 participants (Actual) | Interventional | 2012-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The Brief Assessment of Cognition in Schizophrenia (BACS) is the metric used to characterize cognition in this study. The BACS consists of 6 subscales: Verbal Memory (range 0-75), Working Memory (range 0-28), Motor Speed (range 0-100), Verbal Fluency (measure is total number of words generated in two 60 second trials), Attention and Processing speed (range 0-110), and Executive Function (range 0-22). For each subscale, higher scores reflect better cognition. For each subscale, a Standard Deviation Score was calculated based on normative data (Keefe et al. Norms and standardization of the Brief Assessment of Cognition in Schizophrenia (BACS). Schizophrenia Research 102 (2008) 108-115). The BACS composite score is calculated as the average Standard Deviation Score of the 6 subscale scores. The change in BACS composite score was calculated as the BACS composite score at 8 weeks minus the BACS composite score at baseline. (NCT01696929)
Timeframe: Change in BACS composite score from baseline to 8 weeks
| Intervention | Change in BACS Composite Score (Mean) |
|---|---|
| Tocilizumab | 0.7 |
The Positive and Negative Symptoms Scale (PANSS) is the metric used to characterize psychotic symptoms in this study. The PANSS consists of 30 items, each scored 1-7. The range for the PANSS total score is 30-210. There are 3 subscales - PANSS positive score (range 7-49), PANSS negative score (range 7-49), and PANSS general score (range 16-112). PANSS total score is the summation of these 3 subscales. Higher values for the total and subscale scores reflect more severe psychopathology. A positive change in PANSS total score reflects an increase in psychopathology. A negative change in PANSS total score reflects a decrease in psychopathology. (NCT01696929)
Timeframe: Change in PANSS total score from baseline to 8 weeks
| Intervention | Change in PANSS Total Score (Mean) |
|---|---|
| Tocilizumab | -2.6 |
2 trials available for 3,4-dihydroxyphenylacetic acid and Pregnancy
| Article | Year |
|---|---|
Diazepam and atropine as premedicants: no discrimination by monoamine metabolite and catecholamine measurements in cerebrospinal fluid and plasma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Analgesia, Epidural; Anxiety; Atropine; Cesarean Section; Dia | 1992 |
Biochemical assessment of preoperative stress: a study with diazepam and measurement of monoamine metabolites and catecholamines in cerebrospinal fluid and plasma.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Catecholamines; | 1991 |
149 other studies available for 3,4-dihydroxyphenylacetic acid and Pregnancy
| Article | Year |
|---|---|
Developmental stage-dependent deficits induced by embryonic ethanol exposure in zebrafish: A neurochemical analysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Ethanol; Female; Fetal Alcohol Spectrum Di | 2020 |
Perinatal exposure to bisphenol A causes a disturbance of neurotransmitter metabolic pathways in female mouse offspring: A focus on the tryptophan and dopamine pathways.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Benzhydryl Compounds; Brain; Dopamine; Environmental Pollut | 2020 |
Preventive role of regular low-intensity exercise during adolescence in schizophrenia model mice with abnormal behaviors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Behavior, Animal; Disease Models, Animal; Dopa | 2021 |
A study of the age-related effects of lactational atrazine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Atrazine; Corpus Striatum; Dopamine; Dopamine | 2017 |
Maternal undernutrition during lactation alters nicotine reward and DOPAC/dopamine ratio in cerebral cortex in adolescent mice, but does not affect nicotine-induced nAChRs upregulation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Animals; Anima | 2018 |
Hypothalamus - Response to early paracetamol exposure in male rats offspring.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetaminophen; Amino Acids; Analgesics, Non-Narcotic; Animals; Anima | 2019 |
Biochemical evaluation of the neurotoxicity of MPTP and MPP⁺ in embryonic and newborn mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic | 2013 |
Pre-gestational stress alters stress-response of pubertal offspring rat in sexually dimorphic and hemispherically asymmetric manner.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Animals, Newborn; Body Weight; Catech | 2013 |
Dietary supplementation with resveratrol protects against striatal dopaminergic deficits produced by in utero LPS exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dietary Supplements; Disease Models, Anima | 2014 |
Age-dependent dopaminergic dysfunction following fetal exposure to atrazine in SD rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Atrazine; Corpus Striatum; Dopamine; Dopamine Plasma | 2014 |
A high multivitamin diet fed to Wistar rat dams during pregnancy increases maternal weight gain later in life and alters homeostatic, hedonic and peripheral regulatory systems of energy balance.
Topics: 3,4-Dihydroxyphenylacetic Acid; Abdominal Fat; Age Factors; Animals; Animals, Newborn; Body Weight; | 2015 |
The effects of gestational and chronic atrazine exposure on motor behaviors and striatal dopamine in male Sprague-Dawley rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Atrazine; Behavior, Animal; Cognition; Corpus | 2015 |
The influence of aripiprazole and olanzapine on neurotransmitters level in frontal cortex of prenatally stressed rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antipsychotic Agents; Aripiprazole; Benzodiazepines; Dopami | 2016 |
Dopamine release in organotypic cultures of foetal mouse mesencephalon: effects of depolarizing agents, pargyline, nomifensine, tetrodotoxin and calcium.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Calcium; Dopamine; Dopamine Uptake Inhibitors; Female; Fetu | 2008 |
Prenatal immune activation leads to multiple changes in basal neurotransmitter levels in the adult brain: implications for brain disorders of neurodevelopmental origin such as schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Brain Diseases; Chromatography, High Press | 2009 |
Effect of prenatal exposure to diesel exhaust on dopaminergic system in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Circadian Rhythm; Dopamine; Female; Homovanillic Aci | 2009 |
Prenatal lipopolysaccharide does not accelerate progressive dopamine neuron loss in the rat as a result of normal aging.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Aging; Analysis of Variance; Animals; Body Weight; Brai | 2009 |
A history of iron deficiency anemia during infancy alters brain monoamine activity later in juvenile monkeys.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Anemia, Iron-Deficiency; Animals; Brain; Dopamine; Emot | 2009 |
Augmentation of cocaine-sensitized dopamine release in the nucleus accumbens of adult mice following prenatal cocaine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Hydr | 2009 |
Developmental vitamin D deficiency alters dopamine turnover in neonatal rat forebrain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Catechol O-Methyltransferase; Dopamine; F | 2009 |
Prenatal methamphetamine exposure affects the mesolimbic dopaminergic system and behavior in adult offspring.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Uptake Inhibitors; Animals; Behavior, Animal; Disease Mod | 2009 |
Reduced monoamine oxidase A activity in pregnant smokers and in their newborns.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Cotinine; Female; Fetal Blood; Homovanillic Acid; Humans; Hyd | 2009 |
Acute L: -DOPA effect on hydroxyl radical- and DOPAC-levels in striatal microdialysates of parkinsonian rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Antiparkinson Agents; Corpus Striatum; Disease Models, Anim | 2010 |
Modeling a sensitization stage and a precipitation stage for Parkinson's disease using prenatal and postnatal 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Birth | 2010 |
Prenatal and lactational exposure to low-doses of bisphenol A alters brain monoamine concentration in adult mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Benzhydryl Compounds; Brain; Chromato | 2010 |
Effect of progesterone withdrawal on hypothalamic mechanisms related to prolactin release in late pregnant rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blotting, Western; Chromatography, High Pressure Liquid; Di | 2011 |
Developing brain as an endocrine organ: secretion of dopamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Animals; Blood-Brain Barrier; Brain; Dopamine; | 2012 |
Effects of perinatal exposure to low dose of bisphenol A on anxiety like behavior and dopamine metabolites in brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amygdala; Animals; Anxiety; Benzhydryl Compounds; Dopamine; Endocrin | 2012 |
Adolescent nicotine sensitization and effects of nicotine on accumbal dopamine release in a rodent model of increased dopamine D2 receptor sensitivity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Analysis of Variance; Animals; Animals, Newborn; Brain- | 2013 |
Opioid control of prolactin secretion in late pregnant rats is mediated by tuberoinfundibular dopamine neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Arcuate Nucleus of Hypothalamus; Dopamine; Female; Hypothal | 2002 |
Effects of chronic cocaine on monoamine levels in discrete brain structures of lactating rat dams.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aggression; Animals; Behavior, Animal; Biogenic Monoamines; Brain Ch | 2003 |
Influence of time of day on hypothalamic monoaminergic activity in early pregnancy: effect of a previous reproductive experience.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Circadian Rhythm; Dopamine; Female; Ge | 2003 |
Presynaptic dopaminergic function is largely unaltered in mesolimbic and mesostriatal terminals of adult rats that were prenatally exposed to cocaine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoreceptors; Cocaine; Corpus Striatum; Dopamine; Dopamine | 2003 |
Postnatal weight gain inhibition does not account for neurobehavioral consequences of neonatal Borna disease virus infection.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Analysis of Variance; Animals; Animals, Newborn; Behavior, An | 2003 |
Neonatal ventral hippocampus lesion alters the dopamine content in the limbic regions in postpubertal rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Behavior, Animal; Denervation; Dis | 2004 |
Effects of short-term early gestational exposure to endophyte-infected tall fescue diets on plasma 3,4-dihydroxyphenyl acetic acid and fetal development in mares.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acremonium; Animal Feed; Animals; Ergot Alkaloids; Female; Fetal Dev | 2004 |
Prenatal 3,4-methylenedioxymethamphetamine (ecstasy) exposure induces long-term alterations in the dopaminergic and serotonergic functions in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3,4-Methylenedioxyamphetamine; Adrenergic Uptake Inhibitors; Age Fac | 2005 |
Altered mesencephalic dopaminergic populations in adulthood as a consequence of brief perinatal glucocorticoid exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Dexamethasone; Dopamine; Female; Glucocor | 2005 |
Alterations in central nervous system serotonergic and dopaminergic synaptic activity in adulthood after prenatal or neonatal chlorpyrifos exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain; Chlorpyrifos; Dopamine; Female; Ho | 2005 |
Critical prenatal and postnatal periods for persistent effects of dexamethasone on serotonergic and dopaminergic systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Developmental Disabilities; Dexamethasone; Dopamine; | 2006 |
A comparative study of morphine treatment regimen prior to mating and during late pregnancy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Brain | 2006 |
Postnatal administration of D1 dopamine agonist reverses neonatal dopaminergic lesion-induced changes in striatal enkephalin and substance P systems.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Adrenerg | 2006 |
Mesocortical dopamine and HPA axis regulation: role of laterality and early environment.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenocorticotropic Hormone; Animals; Cerebral Cortex; Chromatograph | 2006 |
Subacute administration of tributyltin chloride modulates neurotransmitters and their metabolites in discrete brain regions of maternal mice and their F1 offspring.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Oral; Animals; Animals, Newborn; Body Weight; Brain; | 2006 |
Differential effects of unilateral olfactory deprivation on noradrenergic and cholinergic systems in the main olfactory bulb of the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Animals, Newborn; Brain Chemistry; Chromatog | 2006 |
Behavioral and neurochemical sensitization to amphetamine following early postnatal administration of methylmercury (MeHg).
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Animals, Newborn; Behavior, Animal; Body Tempe | 2007 |
Dopaminergic mechanisms involved in prolactin release after mifepristone and naloxone treatment during late pregnancy in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Enzyme Inhibitors; Female; Gene Expression Regula | 2006 |
Sex differences in catechol contents in the olfactory bulb of control and unilaterally deprived rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Catechols; Chromatography, High Pressure | 2007 |
Amphetamine and mCPP effects on dopamine and serotonin striatal in vivo microdialysates in an animal model of hyperactivity.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5,6-Dihydroxytryptamine; Age Factors; Amphetamine; Animals; Attentio | 2007 |
Hormonal profile and reproductive performance in lactation deficient (OFA hr/hr) and normal (Sprague-Dawley) female rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Blotting, Western; Caseins; Chromatography, High Pressure L | 2007 |
Development of cocaine sensitization before pregnancy affects subsequent maternal retrieval of pups and prefrontal cortical activity during nursing.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Behavior, Animal; Cocaine; Cocaine-Relate | 2007 |
Maternal high fat diet during the perinatal period alters mesocorticolimbic dopamine in the adult rat offspring: reduction in the behavioral responses to repeated amphetamine administration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Arousal; Central Nervous System Stimulant | 2008 |
Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; An | 2010 |
Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; An | 2010 |
Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; An | 2010 |
Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acoustic Stimulation; Age Factors; Analysis of Variance; Animals; An | 2010 |
Regional changes in monoamine metabolism in the aging constant estrous rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Corpus Striatum; Dopamine; Estrus; Female; Ho | 1984 |
Influence of chronic inorganic lead exposure on regional dopamine and 5-hydroxytryptamine turnover in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Brain; Dopamine; Erythrocytes; Female; Homovanillic | 1984 |
The Genain Quadruplets 25 years later: a diagnostic and biochemical followup.
Topics: 3,4-Dihydroxyphenylacetic Acid; Cyclic AMP; Dopamine beta-Hydroxylase; Environment; Female; Follow-U | 1984 |
Brain neurotransmitter system and chronic lead intoxication.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Brain; Cyclic GMP; Female; gamma-Aminobutyric | 1980 |
Effects of ethanol, given during pregnancy, on the offspring dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dextroamphetamine; Dopamine; Ethanol; Fema | 1983 |
A study of the parameters affecting flow gradient analysis of catecholamines, DOPA and DOPAC by ion pair liquid chromatography with electrochemical detection.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Amniotic Fluid; Animals; Body Fluids; Brain Chemistry; Catech | 1983 |
Enduring behavioural and biochemical effects in the adult rat after prolonged postnatal administration of haloperidol.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Female; Hal | 1981 |
Role of prolactin feedback in the semicircadian rhythm of tuberoinfundibular dopaminergic neuronal activity during early pregnancy in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Circadian Rhythm; Feedback; Female; Haloperidol; Median Emi | 1983 |
Metabolism of 3H-dopamine by human chorioamnion in vitro.
Topics: 3-Methoxy-4-hydroxyphenylethanol; 3,4-Dihydroxyphenylacetic Acid; Chromatography, Ion Exchange; Dopa | 1982 |
Dose-dependent and reversible effects of lead on rat dopaminergic system.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Corpus Striatum; Dopamine; Dose-Response Relationshi | 1981 |
Amniotic fluid catecholamines and metabolites in intrauterine growth retardation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amniotic Fluid; Catecholamines; Dopamine; Epinephrine; Female; Fetal | 1981 |
Maternal smoking and elevation of catecholamines and metabolites in the amniotic fluid.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amniotic Fluid; Catecholamines; Dopamine; Epinephrine; Female; Fetus | 1981 |
Lack of correlation between the neurochemical and behavioural effects induced by d-amphetamine in chronically lead-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Corpus Striatum; Dextroamphetamine; Dopami | 1980 |
An increase in catecholamines and metabolites in the amniotic fluid compartment from middle to late gestation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amniotic Fluid; Catecholamines; Dopamine; Epinephrine; Female; Gesta | 1981 |
Changes in dopamine, serotonin and their metabolites in discrete brain areas of rat offspring after in utero exposure to cocaine or related drugs.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Amitriptyline; Amygdala; Analysis of Variance; Animals; Brain | 1993 |
Acute effects of perinatal hypoxic insult on concentrations of dopamine, serotonin, and metabolites in fetal monkey brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acute Disease; Animals; Brain; Cerebral Cortex; Dopamine; Female; Fe | 1994 |
Neurotoxicity induced by prenatal exposure to MPTP on the monoaminergic and peptidergic systems of the marmoset brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Callithrix; Dopamine; Enkephalin, Methionine; Female | 1995 |
Development of dopamine and N-methyl-D-aspartate systems in rat brain: the effect of prenatal phencyclidine exposure.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Corpus Striatum; Dopamine; Female; | 1993 |
Differential regulation of sympathetic neuron neuropeptide Y and catecholamine content and secretion.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Bucladesine; Calcimycin; Catecholamines; | 1995 |
Permanent dopaminergic alterations in the n. accumbens after prenatal stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Dopamine; Female; Functional Laterality; H | 1994 |
Long-term effects of perinatal asphyxia on basal ganglia neurotransmitter systems studied with microdialysis in rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Aspartic Acid; Asphyxia Neonatorum; Basal Ganglia; Cesarean | 1994 |
Prenatal cocaine administration stimulates fetal brain tyrosine hydroxylase activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Cocaine; Dopamine; Embryonic and Fetal Development; | 1993 |
Effect of cocaine in early gestation on striatal dopamine and neurotrophic activity.
Topics: 3,4-Dihydroxyphenylacetic Acid; Abnormalities, Drug-Induced; Animals; Apoptosis; Cells, Cultured; Ce | 1993 |
Monoamine concentrations in cerebrospinal fluid of fetal and newborn sheep.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Biogenic Monoamines; Dinoprostone; | 1994 |
Changes in brain catecholamine metabolism during bromocriptine treatment in polycystic ovary syndrome.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Brain; Bromocriptine; Catecholamines; Dopamine; Female; Gonad | 1993 |
[The sodium oxybutyrate and nooglutil correction of dopamine release in the striatum of prenatally alcoholized rat pups].
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Ethanol; Female; Glutamates; Mal | 1993 |
Reproductive experience increases striatal and hypothalamic dopamine levels in pregnant rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Female; Homovanillic Acid; Hydro | 1996 |
Ontogeny of striatal dopamine release in rats after acute administration of methamphetamine.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Female; Methamphetamine; Microdi | 1996 |
Postnatal methadone exposure doe not prevent prenatal methadone-induced changes in striatal cholinergic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Animals; Dopamine; Female; Hydroxyindoleacetic Acid; | 1996 |
Exposure to perinatal morphine promotes developmental changes in rat striatum.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Enkephalin, Methionine; Enkephalins; Female; In S | 1996 |
Effects of perinatal exposure to delta 9-tetrahydrocannabinol on the fetal and early postnatal development of tyrosine hydroxylase-containing neurons in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Brain; Dronabinol; Female; Gene Ex | 1996 |
A murine model of prenatal cocaine exposure: effects on the mother and the fetus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animal Nutritional Physiological Phenomena; Animals; Behavior, Anima | 1996 |
Turnover rate and stimulus-evoked release of dopamine by progesterone and N-methyl-D-aspartic acid in rat striatum during pregnancy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Excitatory Amino Acid Agonists; Female; Glutamic | 1996 |
The effects of prenatal exposure to cocaine on the dopaminergic cells in the rat retina. An immunocytochemical and neurochemical study.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Female; Homo | 1996 |
Effects of perinatal asphyxia on the mesostriatal/mesolimbic dopamine system of neonatal and 4-week-old male rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Asphyxia; Basal Ganglia; Dopamine; Female | 1996 |
Long-term reciprocal changes in dopamine levels in prefrontal cortex versus nucleus accumbens in rats born by Caesarean section compared to vaginal birth.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Cesarean Section; Dopamine; Epinephrine; | 1997 |
Pre/postnatal dopamine D1 receptor stimulation induces a differential reduction of serotonin levels in hippocampus and superior colliculus of puber rats.
Topics: 2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine; 3,4-Dihydroxyphenylacetic Acid; Aging; A | 1997 |
Effects of in utero and lactational exposure of the laboratory rat to 2,4,2',4'- and 3,4,3',4'-tetrachlorobiphenyl on dopamine function.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Brain Chemistry; Dopamine; Dose-Response Relat | 1997 |
Rolipram, a selective inhibitor of phosphodiesterase type 4, pronouncedly enhanced the forskolin-induced promotion of dopamine biosynthesis in primary cultured rat mesencephalic neurons.
Topics: 3,4-Dihydroxyphenylacetic Acid; 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2- | 1997 |
Prenatal dexamethasone exposure alters brain monoamine metabolism and adrenocortical response in rat offspring.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Cortex; Aging; Analysis of Variance; Animals; Biogenic Monoa | 1997 |
Evidence for synthesis and release of catecholamines by human amniotic epithelial cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Amnion; Catecholamines; Cells, Cultured; Chrom | 1997 |
Effects of prenatal methylazoxymethanol treatment on striatal dopaminergic systems in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Autoradiography; Brain; Carrier Proteins; Corpus Striatum; | 1998 |
Effect of metyrapone administration in pregnant rats on monoamine concentration in fetal brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenal Glands; Animals; Biogenic Monoamines; Brain; Dopamine; Enzym | 1998 |
Synthesis and release of catecholamines by cultured monkey amniotic epithelial cells.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amnion; Animals; Aromatic-L-Amino-Acid Decarboxylases; Catecholamine | 1998 |
Prenatal stress alters brain biogenic amine levels in primates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Biogenic Amines; Brain; Female; Ho | 1998 |
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2.
Topics: 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic Acid; Animals; Apoptosis; Brain Chemistry; Ca | 1998 |
Reproductive experience reduces striatal dopaminergic responses in freely moving female rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain Chemistry; Chronobiology Phenomena; Dopamine; Dopamin | 1998 |
Behavioural characterization of interleukin-6 overexpressing or deficient mice during agonistic encounters.
Topics: 3,4-Dihydroxyphenylacetic Acid; Agonistic Behavior; Animals; Behavior, Animal; Brain Chemistry; Dopa | 1998 |
Dopamine turnover in the mediobasal hypothalamus in rat fetuses.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cells, Cultured; Dopamine; Female; Fetus; Hypothalamus, Mid | 1999 |
Effects of prenatal exposure to styrene on neurochemical levels in rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Birth Weight; Brain; Brain Chemistry; Dop | 1999 |
Effects of prenatal cocaine exposure on amphetamine-induced dopamine release in the caudate nucleus of the adult rabbit.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Caudate Nucleus; Cocaine; Dopamine; Dopamine U | 1999 |
Effects of neonatal rat Borna disease virus (BDV) infection on the postnatal development of the brain monoaminergic systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Biogenic Monoamines; Borna Disease; Borna | 2000 |
Prenatal hypoxia impairs the postnatal development of neural and functional chemoafferent pathway in rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Afferent Pathways; Animals; Body Temperature; Brain Stem; Catecholam | 2000 |
Regulation of EphB1 expression by dopamine signaling.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Cerebral Cortex; Cocaine; Cocaine-Related | 2000 |
Striatal dopamine sensitization to D-amphetamine in periadolescent but not in adult rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Behavior, Animal; Body Weight; Brain Chemistry; Caud | 2001 |
Parallel induction of the formation of dopamine and its metabolites with induction of tyrosine hydroxylase expression in foetal rat and human cerebral cortical cells by brain-derived neurotrophic factor and glial-cell derived neurotrophic factor.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain-Derived Neurotrophic Factor; Cells, Cultured; Dactino | 2001 |
Dissociation of prolactin secretion from tuberoinfundibular dopamine activity in late pregnant rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Circadian Rhythm; Dopamine; Female; Hypothalamus; Labor, Ob | 2001 |
Lead intoxication during intrauterine life and lactation but not during adulthood reduces nucleus accumbens dopamine release as studied by brain microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Female; Lactation; Lead; Male; Microdialys | 2001 |
Prenatal cocaine exposure increases mesoprefrontal dopamine neuron responsivity to mild stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Cocaine; Cocaine-Related Disorders; Dopamine; Electr | 2001 |
Prenatal exposure to magnetic field increases dopamine levels in the striatum of offspring.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Female; Fetus; Magnetics; Mice; | 2001 |
Effects of prenatal protein malnutrition and neonatal stress on CNS responsiveness.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Corticosterone; Dopamine; Female; Hippoca | 2001 |
Fetal exposure to methamphetamine in utero stimulates development of serotonergic neurons in three-dimensional reaggregate tissue culture.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine-Related Disorders; Animals; Brain; Cell Aggregation; Cel | 2002 |
Pb and Cd poisoning during development alters cerebellar and striatal function in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Abnormalities, Drug-Induced; Animals; Animals, Newborn; Cadmium; Cer | 2002 |
Two novel prolactin release-inhibiting 8 alpha-amino-ergolines.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Embryo Implantation; Ergolines; | 1979 |
Early changes in the development of dopaminergic neurotransmission after maternal exposure to cannabinoids.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain; Cannabinoids; Dopamine; Female; La | 1992 |
Dopaminergic neuron development in rats: biochemical study from prenatal life to adulthood.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Dopamine; Female; Hydroxyindoleacetic Acid; Mesencep | 1992 |
Neurotoxic effect of prenatal exposure to MPTP on the dopaminergic systems of the marmoset brain.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Adolescent; Animals; C | 1992 |
[Studies on catecholamine and its metabolites in the evaluation of fetal distress].
Topics: 3,4-Dihydroxyphenylacetic Acid; Apgar Score; Catecholamines; Female; Fetal Distress; Humans; Labor, | 1992 |
Dopamine content and metabolism in mesencephalic and diencephalic cell cultures: sex differences and effects of sex steroids.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cells, Cultured; Diencephalon; Dopamine; Embryo, Mammalian; | 1991 |
Determination of monoamines and indoles in amniotic fluid by high-performance liquid chromatography-electrochemical detection.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amniotic Fluid; Biogenic Amines; Chromatography, High Pressure Liqui | 1990 |
Biological correlates of mental stress related to anticipated caesarean section.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Anesthesia, Obstetrical; Anesthesia, Spinal; Anxiety; Blood P | 1990 |
Transplacentally-transported 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) affects the catecholamine and indoleamine levels in the fetal mouse brain.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain | 1990 |
Dopaminergic and serotonergic activity in the hypothalamus during early and late pregnancy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Dopamine; Female; Hydroxyindoleacetic Acid | 1991 |
[Significance of umbilical plasma concentrations of catecholamines and their metabolites in patients with term vaginal deliveries].
Topics: 3,4-Dihydroxyphenylacetic Acid; Blood Gas Analysis; Catecholamines; Chromatography, High Pressure Li | 1991 |
Neuroanatomic and neurochemical abnormalities in nonhuman primate infants exposed to weekly doses of ethanol during gestation.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alcohol Drinking; Animals; Brain; Corpus Striatum; Ethanol; Eye; Fem | 1990 |
Rat brain monoamine and Serotonin S2 receptor changes during pregnancy.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Amines; Brain; Corticosterone; Dopamine; Estradiol | 1990 |
Avoidance behavior, prolactin, HVA and DOPAC in offspring of bromopride-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Avoidance Learning; Corpus Striatum; Dopamine; Female; Homo | 1990 |
Altered central monoamine response to D-amphetamine in rats chronically exposed to inorganic lead.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Brain; Dextroamphetamine; Dopamine; Femal | 1985 |
Analysis by HPLC-EC of metabolites of monoamines in fetal and postnatal rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amines; Animals; Animals, Newborn; Brain; Brain Chemistry; Chromatog | 1986 |
Increased interhemispheric coupling of the dopamine systems induced by prenatal stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dominance, Cerebral; Dopamine; Female; Hydroxyindole | 1987 |
Prenatal effects of acute harmaline exposure on fetal brain biogenic amine metabolism.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alkaloids; Animals; Biogenic Amines; Brain Chemistry; Catechol O-Met | 1988 |
Role of serotonin in nocturnal and diurnal surges of prolactin in the pregnant rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Circadian Rhythm; Dopamine; Ergolines; Female; Fenclonine; | 1989 |
[Clinical significance of 3,4-dihydroxyphenyl acetic acid analysis in endocrine tests of the adrenal medulla and sympathetic nervous system].
Topics: 3,4-Dihydroxyphenylacetic Acid; Addison Disease; Adrenal Gland Neoplasms; Adrenal Medulla; Adult; Ag | 1989 |
Interrelation among endogenous catecholamines, prostaglandin F2 alpha and prolactin in last trimester and during parturition.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Catecholamines; Cyclic AMP; Dinoprost; Female; Humans; Labor, | 1989 |
Dopamine, serotonin, and acid metabolites in brain regions from the developing offspring of ethanol-treated rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Chromatography, High Pressure Liqui | 1985 |
Metabolism of amniotic fluid dopamine by fetal membranes.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amniotic Fluid; Dopamine; Extraembryonic Membranes; Female; Humans; | 1989 |
Alterations in behavioral and striatal dopamine asymmetries induced by prenatal stress.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amphetamine; Animals; Behavior, Animal; Body Weight; Caudate Nucleus | 1989 |
Effects of prenatal nicotine exposure on rat striatal dopaminergic and nicotinic systems.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Corpus Striatum; Cotinine; Female; Gestational | 1989 |
Studies on brain monoamine neurotransmitters in mice after prenatal exposure to barbiturate.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Barbiturates; Biogenic Amines; Brain; Brain Stem; Catechola | 1985 |
Maternal stress alters monoamine metabolites in fetal and neonatal rat brain.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amines; Animals; Animals, Newborn; Brain; Diencephalon; Female; Fetu | 1988 |
Correlation between function of the pituitary-thyroid axis and metabolism of catecholamines by the fetus at delivery.
Topics: 3,4-Dihydroxyphenylacetic Acid; Cesarean Section; Delivery, Obstetric; Female; Fetal Blood; Fetus; G | 1987 |
Reactivity to amphetamine in perinatally undernourished rats: behavioral and neurochemical correlates.
Topics: 3,4-Dihydroxyphenylacetic Acid; alpha-Methyltyrosine; Amphetamine; Animals; Behavior, Animal; Brain | 1986 |
Effects of perinatal vitamin B6 deficiency on dopaminergic neurochemistry.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Body Weight; Chromatography, High Pressure Liquid; Corpus S | 1987 |
Stereospecific deuterium substitution at the alpha-carbon position of dopamine and its effect on oxidative deamination catalyzed by MAO-A and MAO-B from different tissues.
Topics: 3,4-Dihydroxyphenylacetic Acid; Aldehydes; Animals; Blood Platelets; Chromatography, High Pressure L | 1986 |
Regional changes in catecholamine content of the pregnant uterus.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Chromatography, High Pressure Liquid; Dopam | 1985 |
Ovulatory function and retinal catecholamine concentrations in female rats with and without inherited retinal photoreceptor degeneration.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Dopamine; Estrus; Female; Light; Luteinizin | 1985 |