Page last updated: 2024-10-17

3,4-dihydroxyphenylacetic acid and Pain

3,4-dihydroxyphenylacetic acid has been researched along with Pain in 11 studies

3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.

Pain: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Research Excerpts

ExcerptRelevanceReference
"The present research examined morphine dose-response effects on both the formalin test and on CNS monoamine (MA) levels and the metabolites dihydroxyphenylacetic acid (DOPAC) and 5-hydroxyindoleacetic acid (5-HIAA) in hypoalgesic (76) and hyperalgesic (SN) strains of domestic fowl."1.28Central monoaminergic changes induced by morphine in hypoalgesic and hyperalgesic strains of domestic fowl. ( Hoganson, DA; Hughes, RA; Sufka, KJ, 1992)
"1."1.28REM sleep deprivation decreases apomorphine-induced stimulation of locomotor activity but not stereotyped behavior in mice. ( Asakura, W; Matsumoto, K; Ohta, H; Watanabe, H, 1992)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's6 (54.55)18.2507
2000's2 (18.18)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pais-Vieira, M1
Mendes-Pinto, MM1
Lima, D1
Galhardo, V1
Finn, DP1
Jhaveri, MD1
Beckett, SR1
Madjd, A1
Kendall, DA1
Marsden, CA1
Chapman, V1
Kvetnanský, R1
Pacák, K1
Sabban, EL1
Kopin, IJ1
Goldstein, DS1
Sufka, KJ1
Hoganson, DA1
Hughes, RA1
Asakura, W1
Matsumoto, K1
Ohta, H1
Watanabe, H1
Antelman, SM2
Caggiula, AR1
Kocan, D2
Knopf, S2
Meyer, D1
Edwards, DJ2
Barry, H1
Boutelle, MG1
Zetterström, T1
Pei, Q1
Svensson, L1
Fillenz, M1
Bertolucci-D'Angio, M1
Serrano, A1
Scatton, B1
France, RD1
Urban, BJ1
Pelton, S1
Kilts, CD1
Hong, JS1
Nemeroff, CB2
Ritchie, JC1
Louilot, A1
Le Moal, M1
Simon, H1

Other Studies

11 other studies available for 3,4-dihydroxyphenylacetic acid and Pain

ArticleYear
Cognitive impairment of prefrontal-dependent decision-making in rats after the onset of chronic pain.
    Neuroscience, 2009, Jul-07, Volume: 161, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amygdala; Animals; Chronic Disease; Cognition; Decision Making; Dise

2009
Behavioral, central monoaminergic and hypothalamo-pituitary-adrenal axis correlates of fear-conditioned analgesia in rats.
    Neuroscience, 2006, Volume: 138, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analgesia; Animals; Behavior, Animal; Biogenic Monoamines; Brain; Co

2006
Stressor specificity of peripheral catecholaminergic activation.
    Advances in pharmacology (San Diego, Calif.), 1998, Volume: 42

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Catecholamines; Cold Temperature; Dihydroxyphenylalanine; E

1998
Central monoaminergic changes induced by morphine in hypoalgesic and hyperalgesic strains of domestic fowl.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain Chemistry; Chickens; Chromatogra

1992
REM sleep deprivation decreases apomorphine-induced stimulation of locomotor activity but not stereotyped behavior in mice.
    General pharmacology, 1992, Volume: 23, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Corpus Striatum; Dopamine; Limbic System; Male

1992
One experience with 'lower' or 'higher' intensity stressors, respectively enhances or diminishes responsiveness to haloperidol weeks later: implications for understanding drug variability.
    Brain research, 1991, Dec-06, Volume: 566, Issue:1-2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Catalepsy; Corticosterone; Deoxygluco

1991
In vivo neurochemical effects of tail pinch.
    Journal of neuroscience methods, 1990, Volume: 34, Issue:1-3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Ascorbic Acid; Brain Chemistry; Chromatography, High Pressu

1990
Differential effects of forced locomotion, tail-pinch, immobilization, and methyl-beta-carboline carboxylate on extracellular 3,4-dihydroxyphenylacetic acid levels in the rat striatum, nucleus accumbens, and prefrontal cortex: an in vivo voltammetric stud
    Journal of neurochemistry, 1990, Volume: 55, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Carbolines; Cerebral Cortex; Corpus Striatum; Electrochemis

1990
CSF monoamine metabolites in chronic pain.
    Pain, 1987, Volume: 31, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Back Pain; Biogenic Amines; Chronic Disease; Depressive

1987
One stressful event blocks multiple actions of diazepam for up to at least a month.
    Brain research, 1988, Apr-05, Volume: 445, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Diazepam; Dopamine; Male; Pain; Pentylenet

1988
Differential reactivity of dopaminergic neurons in the nucleus accumbens in response to different behavioral situations. An in vivo voltammetric study in free moving rats.
    Brain research, 1986, Nov-12, Volume: 397, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Afferent Pathways; Animals; Behavior, Animal; Dopamine; Electrochemi

1986