Page last updated: 2024-10-17

3,4-dihydroxyphenylacetic acid and Myopia

3,4-dihydroxyphenylacetic acid has been researched along with Myopia in 23 studies

3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.

Myopia: A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.

Research Excerpts

ExcerptRelevanceReference
" Dopamine levels may not directly modulate the refractive state of the mouse eye, but tonic levels of dopamine during development may determine susceptibility to myopia."3.80Visually-driven ocular growth in mice requires functional rod photoreceptors. ( Abey, J; Aseem, F; Iuvone, PM; Jabbar, SB; Pardue, MT; Park, Hn; Schmid, G; Sidhu, CS; Tan, CC, 2014)
"Localized image degradation can cause myopia with predominantly axial expansion, myopia with more diffuse vitreous chamber expansion, or eye expansion without myopia."3.73Local patterns of image degradation differentially affect refraction and eye shape in chick. ( Capehart, C; Gill, AS; Lin, T; Liu, J; Pendrak, K; Stone, RA; Sugimoto, R, 2006)
"It has been suggested that ambient lighting at night influences eye growth and might play a causal role in human myopia."3.72Emmetropisation under continuous but non-constant light in chicks. ( Capehart, C; Liu, J; Pendrak, K; Schmid, GF; Stone, RA; Sugimoto, R, 2004)
"To address further a possible role for retinal dopamine in postnatal eye growth, we studied the response of retinal dopamine in eyes of chicks recovering from myopia."3.69Retinal dopamine in the recovery from experimental myopia. ( Capehart, C; Lin, T; Nguyen, T; Pendrak, K; Stone, RA; Zhu, X, 1997)
"Myopia, or nearsightedness, is the most common form of refractive abnormality and is characterized by excessive ocular elongation in relation to ocular power."1.72Melanopsin modulates refractive development and myopia. ( Chakraborty, R; Hattar, S; Iuvone, PM; Landis, EG; Mazade, R; Pardue, MT; Stone, RA; Strickland, R; Yang, V, 2022)
"Monocular myopia was induced by unilateral form-deprivation (FD)."1.48Dopamine Receptor Subtypes Mediate Opposing Effects on Form Deprivation Myopia in Pigmented Guinea Pigs. ( Fan, M; Pan, M; Qu, J; Reinach, PS; Wang, F; Yang, J; Ying, H; Zhang, L; Zhang, S; Zhou, X, 2018)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (13.04)18.2507
2000's3 (13.04)29.6817
2010's14 (60.87)24.3611
2020's3 (13.04)2.80

Authors

AuthorsStudies
Tian, T1
Zou, L1
Wang, S1
Liu, R1
Liu, H1
Chakraborty, R4
Landis, EG3
Mazade, R1
Yang, V2
Strickland, R1
Hattar, S1
Stone, RA5
Iuvone, PM10
Pardue, MT8
Gong, X1
Wu, XH1
Liu, AL1
Qian, KW1
Li, YY1
Ma, YY1
Huang, F1
Wang, Q1
Wu, H1
Zhou, X4
Qu, J3
Yuan, F1
Zhong, YM1
Yang, XL1
Weng, SJ1
Luo, X1
Li, B1
Li, T1
Di, Y1
Zheng, C1
Ji, S1
Ma, Y1
Zhu, J1
Chen, X1
Sun, Y1
Zhao, N1
Liu, W1
Liu, M1
Ju, Z1
Li, J1
Cheng, Z1
Liu, X1
Zhang, S1
Yang, J1
Reinach, PS1
Wang, F1
Zhang, L1
Fan, M1
Ying, H1
Pan, M2
Park, HN3
Dhakal, S1
Motz, CT1
Bergen, MA2
Wang, M1
Aleman, AC1
Schaeffel, F3
Park, H1
Tan, CC2
Faulkner, A1
Jabbar, SB2
Schmid, G2
Abey, J2
Zhang, N1
Favazza, TL1
Baglieri, AM1
Benador, IY1
Noonan, ER1
Fulton, AB1
Hansen, RM1
Akula, JD1
Sidhu, CS2
Aseem, F1
Haque, R1
Fernandes, A2
Lambert, SR1
Cohen, Y2
McGlinn, AM1
Davison, S1
Casavant, S1
Shaffer, J1
Khurana, TS1
Sidhu, C1
He, L1
Markand, S1
Baskin, NL1
Landis, E1
Wetzstein, SA1
Donaldson, KJ1
Priyadarshani, P1
Alderson, SE1
Boatright, JH1
Nickerson, JM1
Dong, F1
Zhi, Z1
Xie, R1
Qin, X1
Lu, R1
Mao, X1
Chen, JF1
Willcox, MD1
Peleg, E1
Belkin, M1
Polat, U1
Solomon, AS1
Liu, J2
Pendrak, K3
Capehart, C3
Sugimoto, R2
Schmid, GF1
Lin, T2
Gill, AS1
Faulkner, AE1
Yin, H1
Williams, RW1
Pozdeyev, N1
Guo, SS1
Sivak, JG1
Callender, MG1
Diehl-Jones, B1
Rickers, M1
Nguyen, T1
Zhu, X1

Other Studies

23 other studies available for 3,4-dihydroxyphenylacetic acid and Myopia

ArticleYear
The Role of Dopamine in Emmetropization Modulated by Wavelength and Temporal Frequency in Guinea Pigs.
    Investigative ophthalmology & visual science, 2021, 09-02, Volume: 62, Issue:12

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Axial Length, Eye; Chromatography, High Pressure Liquid; Do

2021
Melanopsin modulates refractive development and myopia.
    Experimental eye research, 2022, Volume: 214

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Axial Length, Eye; Cornea; Disease Models, Animal; Dopamine

2022
Optic nerve crush modulates refractive development of the C57BL/6 mouse by changing multiple ocular dimensions.
    Brain research, 2020, 01-01, Volume: 1726

    Topics: 3,4-Dihydroxyphenylacetic Acid; Amacrine Cells; Animals; Cornea; Dopamine; Mice, Inbred C57BL; Myopi

2020
Myopia induced by flickering light in guinea pig eyes is associated with increased rather than decreased dopamine release.
    Molecular vision, 2017, Volume: 23

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Axial Length, Eye; Blotting, Western; Chromatography, High

2017
Study of Vesicular Monoamine Transporter 2 in Myopic Retina Using [
    Molecular imaging and biology, 2018, Volume: 20, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Fluorine Radioisotopes; Guinea Pigs; Homovanillic

2018
Dopamine Receptor Subtypes Mediate Opposing Effects on Form Deprivation Myopia in Pigmented Guinea Pigs.
    Investigative ophthalmology & visual science, 2018, 09-04, Volume: 59, Issue:11

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Disease Models, Anima

2018
Lack of cone mediated retinal function increases susceptibility to form-deprivation myopia in mice.
    Experimental eye research, 2019, Volume: 180

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Disease Models, Anima

2019
Probing the Potency of Artificial Dynamic ON or OFF Stimuli to Inhibit Myopia Development.
    Investigative ophthalmology & visual science, 2019, 06-03, Volume: 60, Issue:7

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Animals; Animals, Newborn; Chickens; Choroid; Chromatography,

2019
Retinal degeneration increases susceptibility to myopia in mice.
    Molecular vision, 2013, Volume: 19

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Disease Susceptibility; Dopamine; Mice; Mice, Inbred C57BL;

2013
The rat with oxygen-induced retinopathy is myopic with low retinal dopamine.
    Investigative ophthalmology & visual science, 2013, Dec-19, Volume: 54, Issue:13

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Blotting, Western; Chromatography, High P

2013
Visually-driven ocular growth in mice requires functional rod photoreceptors.
    Investigative ophthalmology & visual science, 2014, Sep-02, Volume: 55, Issue:10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Disease Models, Anima

2014
Neonatal aphakia is associated with altered levels of dopamine metabolites in the non-human primate retina.
    Experimental eye research, 2015, Volume: 140

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Aphakia, Postcataract; Axial Length, Eye;

2015
Development of Experimental Myopia in Chicks in a Natural Environment.
    Investigative ophthalmology & visual science, 2016, 09-01, Volume: 57, Issue:11

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Chickens; Circadian Rhythm; Dark Adaptati

2016
Altered Refractive Development in Mice With Reduced Levels of Retinal Dopamine.
    Investigative ophthalmology & visual science, 2016, Aug-01, Volume: 57, Issue:10

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Biomarkers; Disease Models, Animal; Disease Progress

2016
IRBP deficiency permits precocious ocular development and myopia.
    Molecular vision, 2016, Volume: 22

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Axial Length, Eye; Disease Models, Animal; Dopamine; Eye; E

2016
Inhibition of experimental myopia by a dopamine agonist: different effectiveness between form deprivation and hyperopic defocus in guinea pigs.
    Molecular vision, 2011, Volume: 17

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Apomorphine; Biometry; Dopamine Agonists; Dose-Response Rel

2011
Ambient illuminance, retinal dopamine release and refractive development in chicks.
    Experimental eye research, 2012, Volume: 103

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Axial Length, Eye; Chickens; Chromatograp

2012
Emmetropisation under continuous but non-constant light in chicks.
    Experimental eye research, 2004, Volume: 79, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chickens; Circadian Rhythm; Dopamine; Eye; Light; Models, A

2004
Local patterns of image degradation differentially affect refraction and eye shape in chick.
    Current eye research, 2006, Volume: 31, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Animals, Newborn; Chickens; Chromatography, High Pressure L

2006
High susceptibility to experimental myopia in a mouse model with a retinal on pathway defect.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Disease Models, Anima

2008
Retinal dopamine and lens-induced refractive errors in chicks.
    Current eye research, 1995, Volume: 14, Issue:5

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chickens; Chromatography, High Pressure Liquid; Contact Len

1995
Dose-dependent effects of intravitreal pirenzepine on deprivation myopia and lens-induced refractive errors in chickens.
    Experimental eye research, 1995, Volume: 61, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chickens; Dopamine; Electroretinography; Hyperopia; Myopia;

1995
Retinal dopamine in the recovery from experimental myopia.
    Current eye research, 1997, Volume: 16, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chickens; Dopamine; Eye; Female; Male; Myopia; Retina; Sens

1997