3,4-dihydroxyphenylacetic acid has been researched along with Muscle Rigidity in 8 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Muscle Rigidity: Continuous involuntary sustained muscle contraction which is often a manifestation of BASAL GANGLIA DISEASES. When an affected muscle is passively stretched, the degree of resistance remains constant regardless of the rate at which the muscle is stretched. This feature helps to distinguish rigidity from MUSCLE SPASTICITY. (From Adams et al., Principles of Neurology, 6th ed, p73)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Oral administration of 10% solution of Phytomix-40 (multicomponent plant phytoadaptogen) to C57Bl/6 mice with MPTP-induced Parkinson's syndrome alleviated symptoms (oligokinesia and muscle rigidity), compensated for the deficiency of dopamine and its metabolites (DOPAC and homovanillic acid), and reduced the level of lipid peroxides in the striatum." | 3.73 | Effect of complex phytoadaptogen on MPTP-induced Parkinson's syndrome in mice. ( Belorustseva, SA; Bocharov, EV; Bocharova, OA; Kryzhanovskii, GN; Kucheryanu, VG; Kudrin, VS, 2006) |
| " Behavioral deficits at the end of the 14-day dosing regime and on day 28 (i." | 1.40 | Intranasal administration of alpha-synuclein aggregates: a Parkinson's disease model with behavioral and neurochemical correlates. ( Davydova, TV; Fomina, VG; Gruden, MA; Kudrin, VS; Morozova-Roche, LA; Narkevich, VB; Sewell, RD; Wang, C, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gruden, MA | 1 |
| Davydova, TV | 1 |
| Narkevich, VB | 1 |
| Fomina, VG | 1 |
| Wang, C | 1 |
| Kudrin, VS | 3 |
| Morozova-Roche, LA | 1 |
| Sewell, RD | 1 |
| Bocharov, EV | 1 |
| Kucheryanu, VG | 1 |
| Kryzhanovskii, GN | 2 |
| Bocharova, OA | 1 |
| Belorustseva, SA | 1 |
| Genç, E | 1 |
| Havemann, U | 1 |
| Tzoneva-Tyutyulkova, N | 1 |
| Kuschinsky, K | 1 |
| Kucherianu, VG | 1 |
| Iurasov, VV | 1 |
| Nikushkin, EV | 1 |
| Zhigal'tsev, IV | 1 |
| Lindner, MD | 1 |
| Cain, CK | 1 |
| Plone, MA | 1 |
| Frydel, BR | 1 |
| Blaney, TJ | 1 |
| Emerich, DF | 1 |
| Hoane, MR | 1 |
| Antkiewicz-Michaluk, L | 1 |
| Michaluk, J | 1 |
| Mokrosz, M | 1 |
| Romanska, I | 1 |
| Lorenc-Koci, E | 1 |
| Ohta, S | 1 |
| Vetulani, J | 1 |
| Calderini, G | 1 |
| Consolazione, A | 1 |
| Garattini, S | 1 |
| Algeri, S | 1 |
| Jolicoeur, FB | 1 |
| Rivest, R | 1 |
| Drumheller, A | 1 |
8 other studies available for 3,4-dihydroxyphenylacetic acid and Muscle Rigidity
| Article | Year |
|---|---|
Intranasal administration of alpha-synuclein aggregates: a Parkinson's disease model with behavioral and neurochemical correlates.
Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; alpha-Synuclein; Amyloid; Animals; Corpu | 2014 |
Effect of complex phytoadaptogen on MPTP-induced Parkinson's syndrome in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dopa | 2006 |
Motility, rigidity and turnover of dopamine in the striatum after administration of morphine to rats: a re-evaluation of their mechanisms.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Kainic Acid; Male; Morphine; Mot | 1983 |
[Effect of acidic fibroblast growth factor on experimental parkinsonism and levels of dopamine and its metabolites in the striatum of mice of various ages].
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 3,4-Dihydroxyphenylacetic Acid; Administration, Intran | 1999 |
Incomplete nigrostriatal dopaminergic cell loss and partial reductions in striatal dopamine produce akinesia, rigidity, tremor and cognitive deficits in middle-aged rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Brain Mapping; Corpus Striatum; Dementia; Dopa | 1999 |
Different action on dopamine catabolic pathways of two endogenous 1,2,3,4-tetrahydroisoquinolines with similar antidopaminergic properties.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Dopamine Antagonists; Homovanill | 2001 |
Different effects of methionine-enkephalin and (D-Ala2)methionine-enkephalin amide on the metabolism of dopamine and norephinephrine in rat brain:fact or artifact?
Topics: 3,4-Dihydroxyphenylacetic Acid; Amino Acid Sequence; Animals; Behavior, Animal; Brain; Dopamine; End | 1978 |
Hypokinesia, rigidity, and tremor induced by hypothalamic 6-OHDA lesions in the rat.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Dopamine; Dyskinesia, Drug-Induced; Homovanillic Aci | 1991 |