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3,4-dihydroxyphenylacetic acid and Movement Disorders

3,4-dihydroxyphenylacetic acid has been researched along with Movement Disorders in 20 studies

3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
"Two cases of severe dystonia and dyskinesia were treated with talipexole, a dopamine autoreceptor agonist, and the metabolites of dopamine, norepinephrine, and serotonin in cerebrospinal fluid (CSF) were determined."3.68Chronic treatment with talipexole dihydrochloride on abnormal involuntary movement in humans. ( Koga, I; Nishikawa, T; Tanaka, M; Tsuda, A; Uchida, Y; Yamada, S, 1990)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19906 (30.00)18.7374
1990's5 (25.00)18.2507
2000's5 (25.00)29.6817
2010's4 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ngwa, HA1
Kanthasamy, A1
Jin, H1
Anantharam, V1
Kanthasamy, AG1
Masoud, ST1
Vecchio, LM1
Bergeron, Y1
Hossain, MM1
Nguyen, LT1
Bermejo, MK1
Kile, B1
Sotnikova, TD1
Siesser, WB1
Gainetdinov, RR1
Wightman, RM1
Caron, MG1
Richardson, JR1
Miller, GW1
Ramsey, AJ1
Cyr, M1
Salahpour, A1
Willard, AM1
Bouchard, RS1
Gittis, AH1
Morelli, E1
Moore, H1
Rebello, TJ1
Gray, N1
Steele, K1
Esposito, E1
Gingrich, JA1
Ansorge, MS1
Kato, H1
Kurosaki, R1
Oki, C1
Araki, T1
de Lago, E1
Fernández-Ruiz, J1
Ortega-Gutiérrez, S1
Cabranes, A1
Pryce, G1
Baker, D1
López-Rodríguez, M1
Ramos, JA1
Jeste, DV1
Doongaji, DR1
Linnoila, M1
Kontur, PJ1
al-Tikriti, M1
Innis, RB1
Roth, RH1
Campbell, JM1
Gilmore, DP1
Russell, D1
Growney, CA1
Favor, G1
Weir, J1
Stone, TW1
Payne, AP1
Paul, G1
Reum, T1
Meissner, W1
Marburger, A1
Sohr, R1
Morgenstern, R1
Kupsch, A1
Hyland, K1
Beaman, BL1
LeWitt, PA1
DeMaggio, AJ1
Campbell, BM1
Gresch, PJ1
Walker, PD1
Nishikawa, T1
Yamada, S1
Tsuda, A1
Tanaka, M1
Koga, I1
Uchida, Y1
Dávila, R1
Andía, I1
Miller, JC1
Friedhoff, AJ1
Guimón, J1
Apicella, P1
Trouche, E1
Nieoullon, A1
Legallet, E1
Dusticier, N1
Bradbury, AJ2
Costall, B2
Domeney, AM2
Testa, B1
Jenner, PG1
Marsden, CD2
Naylor, RJ2
Jenner, PJ1
Kostic, V1
Djuricic, B1
Paschen, W1
Cross, AJ1
Crow, TJ1
Ferrier, IN1
Johnson, JA1
Johnstone, EC1
Owen, F1
Owens, DG1
Poulter, M1
Bourke, CA1

Other Studies

20 other studies available for 3,4-dihydroxyphenylacetic acid and Movement Disorders

ArticleYear
Vanadium exposure induces olfactory dysfunction in an animal model of metal neurotoxicity.
    Neurotoxicology, 2014, Volume: 43

    Topics: 3,4-Dihydroxyphenylacetic Acid; Administration, Intranasal; Animals; Disease Models, Animal; Dopamin

2014
Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.
    Neurobiology of disease, 2015, Volume: 74

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Anti-Dyskinesia Agents; Cell Death; Cytosol; Dopamine; Dopa

2015
Differential degradation of motor deficits during gradual dopamine depletion with 6-hydroxydopamine in mice.
    Neuroscience, 2015, Aug-20, Volume: 301

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic Agents; Animals; Chromatography, High Pressure Liquid; Di

2015
Chronic 5-HT transporter blockade reduces DA signaling to elicit basal ganglia dysfunction.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Nov-02, Volume: 31, Issue:44

    Topics: 3,4-Dihydroxyphenylacetic Acid; Age Factors; Animals; Animals, Newborn; Basal Ganglia; Cell Count; C

2011
Arundic acid, an astrocyte-modulating agent, protects dopaminergic neurons against MPTP neurotoxicity in mice.
    Brain research, 2004, Dec-24, Volume: 1030, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Astrocytes; Caprylates; Cell Communication; Dopamine; Glial

2004
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2006, Volume: 16, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Arachidonic Acids; Brain Chemistry; D

2006
Elevated cerebrospinal fluid noradrenaline in tardive dyskinesia.
    The British journal of psychiatry : the journal of mental science, 1984, Volume: 144

    Topics: 3,4-Dihydroxyphenylacetic Acid; Adult; Aged; Antipsychotic Agents; Dyskinesia, Drug-Induced; Homovan

1984
Postmortem stability of monoamines, their metabolites, and receptor binding in rat brain regions.
    Journal of neurochemistry, 1994, Volume: 62, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Brain Chemistry; Dopamine; Huma

1994
Extracellular levels of dopamine and its metabolite 3,4-dihydroxy-phenylacetic acid measured by microdialysis in the corpus striatum of conscious AS/AGU mutant rats.
    Neuroscience, 1998, Volume: 85, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Extracellular Space; Male; Micro

1998
High frequency stimulation of the subthalamic nucleus influences striatal dopaminergic metabolism in the naive rat.
    Neuroreport, 2000, Feb-28, Volume: 11, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Electric Stimulation; Extracellu

2000
Monoamine changes in the brain of BALB/c mice following sub-lethal infection with Nocardia asteroides (GUH-2).
    Neurochemical research, 2000, Volume: 25, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Biogenic Monoamines; Brain; Cerebellum; Dopamine; Female; H

2000
Neonatal dopamine depletion reveals a synergistic mechanism of mRNA regulation that is mediated by dopamine(D1) and serotonin(2) receptors and is targeted to tachykinin neurons of the dorsomedial striatum.
    Neuroscience, 2001, Volume: 105, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Animals, Newborn; Dopamine; Dopamine Agonists; Dopam

2001
Chronic treatment with talipexole dihydrochloride on abnormal involuntary movement in humans.
    Clinical neuropharmacology, 1990, Volume: 13, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Azepines; Dopamine Agents; Dystonia; Homovanillic Acid; Humans

1990
Evidence of low dopaminergic activity in elderly women with spontaneous orofacial dyskinesia.
    Acta psychiatrica Scandinavica, 1991, Volume: 83, Issue:1

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Aged, 80 and over; Dopamine; Estradiol; Facial Muscles; Female

1991
Motor impairments and neurochemical changes after unilateral 6-hydroxydopamine lesion of the nigrostriatal dopaminergic system in monkeys.
    Neuroscience, 1990, Volume: 38, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Choline O-Acetyltransferase; Corpus Striatum; Dopami

1990
The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety.
    Neuroscience letters, 1985, Oct-24, Volume: 61, Issue:1-2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic

1985
The neurotoxic actions of 6-hydroxydopamine infused into the rat substantia nigra.
    Neuroscience letters, 1986, Jun-18, Volume: 67, Issue:2

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; 3,4-Dihydroxyphenylacetic

1986
Hemiballismus: changes in cerebrospinal fluid.
    Acta neurologica Scandinavica, 1988, Volume: 78, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aged; Dominance, Cerebral; Dopamine; Female; Homovanillic Acid; Huma

1988
Chemical and structural changes in the brain in patients with movement disorder.
    Psychopharmacology. Supplementum, 1985, Volume: 2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Acetylcholine; Antipsychotic Agents; Brain; Choline O-Acetyltransfer

1985
A novel nigrostriatal dopaminergic disorder in sheep affected by Tribulus terrestris staggers.
    Research in veterinary science, 1987, Volume: 43, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Efferent Pathways; Female; Levod

1987