3,4-dihydroxyphenylacetic acid has been researched along with Morphine Dependence in 9 studies
3,4-Dihydroxyphenylacetic Acid: A deaminated metabolite of LEVODOPA.
(3,4-dihydroxyphenyl)acetic acid : A dihydroxyphenylacetic acid having the two hydroxy substituents located at the 3- and 4-positions. It is a metabolite of dopamine.
dihydroxyphenylacetic acid : A dihydroxy monocarboxylic acid consisting of phenylacetic acid having two phenolic hydroxy substituents.
Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with yohimbine (alpha(2)-adrenoceptor) or prazosin (alpha(1)-adrenoceptor) 15 min prior to naloxone administration attenuated some of the behavioural signs of morphine withdrawal." | 5.31 | Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors. ( Laorden, ML; Milanés, MV, 2000) |
| " The aim of our study was to investigate abnormalities in the mesolimbic pathway associated with morphine dependence and withdrawal." | 3.81 | Dysregulation of dopaminergic regulatory mechanisms in the mesolimbic pathway induced by morphine and morphine withdrawal. ( García-Pérez, D; Laorden, ML; López-Bellido, R; Milanés, MV; Núñez, C; Rodríguez, RE, 2015) |
| "Pretreatment with yohimbine (alpha(2)-adrenoceptor) or prazosin (alpha(1)-adrenoceptor) 15 min prior to naloxone administration attenuated some of the behavioural signs of morphine withdrawal." | 1.31 | Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors. ( Laorden, ML; Milanés, MV, 2000) |
| "Treatment with naloxone of morphine-exposed mice resulted in the typical jumping behavior indicative of opiate withdrawal." | 1.28 | Modifications of striatal D2 dopaminergic postsynaptic sensitivity during development of morphine tolerance-dependence in mice. ( Cebeira, M; Fernández-Ruiz, JJ; Hernández, ML; Navarro, M; Ramos, JA; Rodriguez de Fonseca, F, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 4 (44.44) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| García-Pérez, D | 1 |
| López-Bellido, R | 1 |
| Rodríguez, RE | 1 |
| Laorden, ML | 4 |
| Núñez, C | 1 |
| Milanés, MV | 4 |
| San-Martín-Clark, O | 1 |
| Cuéllar, B | 1 |
| De Alba, J | 1 |
| Leza, JC | 1 |
| Lorenzo, P | 1 |
| Schrater, PR | 1 |
| Russo, AC | 1 |
| Stanton, TL | 1 |
| Newman, JR | 1 |
| Rodriguez, LM | 1 |
| Beckman, AL | 1 |
| Fuertes, G | 1 |
| Fuente, T | 1 |
| Zhou, Q | 1 |
| Nyberg, F | 1 |
| Navarro, M | 1 |
| Fernández-Ruiz, JJ | 1 |
| Rodriguez de Fonseca, F | 1 |
| Hernández, ML | 1 |
| Cebeira, M | 1 |
| Ramos, JA | 1 |
| Glick, SD | 1 |
| Merski, C | 1 |
| Steindorf, S | 1 |
| Wang, S | 1 |
| Keller, RW | 1 |
| Carlson, JN | 1 |
9 other studies available for 3,4-dihydroxyphenylacetic acid and Morphine Dependence
| Article | Year |
|---|---|
Dysregulation of dopaminergic regulatory mechanisms in the mesolimbic pathway induced by morphine and morphine withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Disease Models, Animal; Dopamine; Gen | 2015 |
Changes induced by sodium cromoglycate in brain catecholamine turnover in morphine dependent and abstinent mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Brain; Brain Chemistry; Catecholamines; Cerebral Cortex; Cr | 1995 |
Changes in striatal dopamine metabolism during the development of morphine physical dependence in rats: observations using in vivo microdialysis.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Chromatography, High Pressure Liquid; Corpus Striatum; Dial | 1993 |
Noradrenergic and dopaminergic activity in the hypothalamic paraventricular nucleus after naloxone-induced morphine withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Analysis of Variance; Animals; Behavior, Animal; Body Weight; Chroni | 2000 |
Catecholaminergic activity and 3',5'-cyclic adenosine monophosphate levels in heart right ventricle after naloxone induced withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Behavior, Animal; Catecholamines; Cyclic AMP; Dopamine; Hea | 2000 |
Changes in catecholaminergic pathways innervating the rat heart ventricle during morphine dependence. Involvement Of alpha(1)- and alpha(2)-adrenoceptors.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adrenergic alpha-Antagonists; Analgesics, Opioid; Animals; Catechola | 2000 |
Injection of substance P (SP) N-terminal fragment SP(1-7) into the ventral tegmental area modulates the levels of nucleus accumbens dopamine and dihydroxyphenylacetic acid in male rats during morphine withdrawal.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Dopamine; Extracellular Space; Male; Microdialysis; Morphin | 2002 |
Modifications of striatal D2 dopaminergic postsynaptic sensitivity during development of morphine tolerance-dependence in mice.
Topics: 3,4-Dihydroxyphenylacetic Acid; Adenylyl Cyclases; Animals; Brain Chemistry; Corpus Striatum; Cyclic | 1992 |
Neurochemical predisposition to self-administer morphine in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cerebral Cortex; Corpus Striatum; Female; Homovanillic Acid | 1992 |